MADS-box BSISTER transcription factors regulate stilbenes biosynthesis in grapes by directly binding to the promoter of STS48.

Stilbenes constitute a class of naturally occurring polyphenolic compounds that have been identified in a wide range of plants. In wine, stilbenes play crucial roles in humans, exhibiting anti-cancer, anti-inflammatory, antioxidant properties, and aiding in the prevention of cardiovascular diseases. Therefore, studies on the synthesis and regulatory mechanisms of styrene compounds in grapes are of great economic importance.

Bifunctional nanobody facilitates a colorimetric and fluorescent dual-mode immunoassay of Staphylococcal enterotoxin A.

Immunoassay is a diagnostic tool based on the specific binding of antibodies and antigens with widespread applications. Nonetheless, several research obstacles, like poor specific antibodies, the poisonous reagents and unstable results, still remain challenges. Herein, we innovatively reported a colorimetric and fluorescent dual-mode immunoassay based on the bifunctional nanobody for SEA detection.

MdMYB54 reduces disease severity caused by Fusarium solani in apple by modulating cell wall cellulose and pectate lyase-dependent defense.

The plant cell wall is the first barrier against pathogen invasion. Fusarium solani is the primary pathogen responsible for apple replant disease. In this study, we identified an MYB protein, MdMYB54, which interacts with the positive regulator of F.

Development of a β-lactamase-based aggregation-induced emission lateral flow strip for the detection of clavulanic acid in Milk.

Lack of biorecognition elements significantly hinders the development of rapid detection methods for clavulanic acid (CA). To address this, we expressed Class A β-lactamases PC1 in vitro and demonstrated its high affinity for CA. Then we investigated the recognition mechanisms of PC1 for CA and identified key contact amino acids: Ser70, Lys73, Ser130, Glu166, and Lys234.

Map-based cloning revealed BhAPRR2 gene regulating the black peel formation of mature fruit in wax gourd (Benincasa hispida).

Map-based cloning revealed BhAPRR2, encoding a two-component response-regulating protein that regulates the black peel formation of mature fruit in wax gourd. Wax gourd is an economically significant vegetable crop, and peel color is a crucial agronomic trait that influences its commercial value. Although genes controlling light green or white peel have been cloned in wax gourd, the genetic basis and molecular mechanism underlying black peel remain unclear.

Modulating the highland barley hordein/glutelin ratio can improve reconstituted fermented dough characteristics to promote Chinese Mantou quality.

To improve the defective processing of barley fermented dough, this study constructed barley model dough using reconstituted hordein/glutelin ratios (75:25, 50:50, and 25:75) and elucidated its regulatory roles and potential mechanisms. SEM and CLSM results showed that increasing the hordein ratio improved the continuity and completion of the reconstituted gluten network compared to Control, thus allowing the gluten to stretch and elongate during fermentation. Also, LF-NMR revealed that the water distribution of the reconstituted system tended to shift from a free to a bound state, contributing to water retention during the dough hydration phase.

A comprehensive study on fermentation and aroma contributions of Torulaspora delbrueckii in diverse wine varieties: Insights from pure and co-fermentation studies.

As a well-commercialized and utilized non-Saccharomyces yeast, Torulaspora delbruineckii is gaining increasing relevance in the winemaking industry. However, its ability to produce distinctive aromas in wine has been inconsistently reported in the literature. This study aimed to evaluate the fermentation performance and aroma properties of T.

A fluorescent aptasensor for deoxynivalenol detection based on Nb.BbvCI-assisted targeted-responsive three-way junctions integrated DNA walking machine.

Deoxynivalenol (DON) contamination in cereals is a widespread issue with global implications, necessitating the development of efficient detection methods. Here, a fluorescent aptasensor integrating target-responsive DNA three-way junction (TWJ) and DNA walking machine was developed to detect DON. The DON-specific aptamer (Apt) and the walker (Walker DNA) are integrated into TWJs.

MdHY5 positively regulates cold tolerance in apple by integrating the auxin and abscisic acid pathways.

Low-temperature stress causes various types of physiological and biochemical damage to plants. The basic leucine zipper (bZIP) family transcription factor HY5 plays a significant role in multiple stress responses in plants. Here, cold stress was found to induce the upregulation of MdHY5 expression, which, in turn, positively regulates the cold tolerance of apple (Malus domestica).

Promoting effect of oxygen vacancies in CuZnO-2/peroxymonosulfate system on the p-arsanilic acid degradation and secondary arsenic species immobilization.

Combining chemical oxidation and adsorption is highly desirable but challenging to remove organoarsenic compounds for water purification. Herein, we prepared a Zn-doped CuO (CuZnO-2) catalyst by incorporating Zn atoms into the CuO lattice, which results in abundant surface oxygen vacancies (OVs) and modulates the electronic structure of Cu-OVs-Zn sites for PMS activation to degrade p-arsanilic acid (p-ASA) and adsorb the secondary arsenic species simultaneously. The elevated d-band centers for Cu upward to the Fermi level can significantly strengthen the adsorption of PMS, p-ASA, and the generated arsenic species.

The formation and performance tuning mechanism of starch-based hydrogels.

Starch-based hydrogels, characterized by their three-dimensional network structures, are increasingly explored for their biodegradability, low cost, and abundance of modifiable hydroxyl groups. However, a comprehensive understanding of the mechanisms behind the formation and property modulation of these hydrogels has not been systematically described. Drawing from literature of the past decade, this review provides insights into designing multifunctional starch-based hydrogels through various gelation mechanism, crosslinking strategies, and second-network structure.

Chitosan and gelatin based sprayable hydrogels incorporating photothermal and long-acting antibiotic sterilization for infected wound management with shape adaptability.

Severe skin damage resulting from acute trauma is often accompanied by uncontrolled bleeding, microbial infections, and delayed wound healing. Herein, multifunctional sprayable hydrogels (CT-CS-ZIF@CIP Gel) were developed for wound management by incorporating antibacterial nanoplatforms (CT-CS-ZIF@CIP) into photocurable gels consisting of chitosan methacrylate and gallic acid grafted gelatin. The nanoplatform was initially constructed by sequentially loading CuSe (CS) and ciprofloxacin-decorated zeolitic imidazolate framework-8 (ZIF@CIP) onto Cu-doped Ti MOF (CT), in which CS served as a photothermal agent, ZIF enabled pH-responsive release of CIP, and CT acted as carriers for CS and ZIF@CIP.

Coccinic acid exhibits anti-tumor efficacy against NSCLC harboring EGFR L858R/T790M mutation via the EGFR/STAT3 pathway.

Epidermal growth factor receptor (EGFR) is a starring target for the treatment of non-small cell lung cancer (NSCLC). EGFR tyrosine kinase inhibitors (EGFR-TKIs) have been used to treat NSCLC patients with EGFR-activating mutations. However, most patients invariably develop resistance to these agents due to the occurrence of novel mutations at the EGFR kinase domain.

Understanding the formation and mitigation of chloropropanol esters during traditional Chinese cooking using a lipase hydrolysis-based method.

Chloropropanol esters are major contaminants in food, but their formation during traditional Chinese cooking remains unclear. In this study, a method based on lipase hydrolysis pretreatment was developed and validated to determine 4 chloropropanol esters. The formation of these esters during stir-frying and hotpot cooking under various conditions was investigated.

A new genus from southern China in the tribe Nicertini and discussion of distinguishing tribes of Derbinae (Hemiptera: Fulgoromorpha: Derbidae).

A new genus, Neomegatropis gen. nov., in the tribe Nicertini (Hemiptera: Fulgoromorpha: Derbidae) is described from China with one new species, Neomegatropis rubrimacula sp.

Taxonomy of the leafhopper genus Varicopsella (Hemiptera: Cicadellidae: Eurymelinae: Macropsini) with description of a new species from Thailand.

The leafhopper genus Varicopsella is reviewed and a new species, Varicopsella cornifera sp. nov., from Thailand is described and illustrated.

Eight new species and four new records of the leafhopper genus Agnesiella Dworakowska (Hemiptera: Cicadellidae: Typhlocybinae) from China.

Eight new species of the leafhopper genus Agnesiella Dworakowska are described and illustrated, including Agnesiella (Agnesiella) hamaculeata, A. (A.) nigroflava, A.

New species and records of subgenus Aethina from China (Coleoptera: Nitidulidae).

Two new species of sap beetles, A. (A.) similinconspicua sp.

Taxonomic study of the leafhopper genus Tautoneura Anufriev with four new species and one new record, and one new species for Qadria Mahmood (Hemiptera: Cicadellidae: Typhlocybinae: Erythroneurini) from China.

The genus Tautoneura Anufriev is reviewed with four new species and one new record from China: T. apicidentata, T. bicruris, T.

First record of the leafhopper genus Pedionis (Hemiptera: Cicadellidae: Eurymelinae: Macropsini) from Malaysia with description of a new species.

The genus Pedionis with its species Pedionis (Pedionis) rufoscutellata Huang & Viraktamath, 1993 is recorded for the first time from Malaysia. A new species Pedionis (Pedionis) spiculata sp. nov.

A review of the cicada genus Mata Distant, 1906 (Hemiptera: Cicadidae) with description of one new species from China.

The cicada genus Mata Distant, 1906 was reviewed based on the description of one new species, Mata uncinulata sp. nov., from China.

Glutathione transferase VvGSTU60 is essential for proanthocyanidin accumulation and cooperates synergistically with MATE in grapes.

Proanthocyanidin, synthesized in the endoplasmic reticulum and stored in vacuoles, is key to grape and wine quality. Glutathione S-transferase (GST) plays a crucial role in proanthocyanidin accumulation. However, little is known about the mechanisms of GSTs in the process.

Competitive binding of small antagonistic peptides to the OsER1 receptor optimizes rice panicle architecture.

Rice panicle architecture is a pivotal trait that strongly contributes to grain yield. Small peptide ligands from the OsEPF/EPFL family synergistically control panicle architecture by recognition of the OsER1 receptor and subsequent activation of the OsMKKK10-OsMKK4-OsMPK6 cascade, indicating that specific ligand-receptor pairs orchestrate rice panicle development. However, how small homologous peptides fine-tune organ morphogenesis by targeting a common receptor remains elusive.