miR-142 downregulation alleviates the impairment of spatial learning and memory, reduces the level of apoptosis, and upregulates the expression of pCaMKII and BAI3 in the hippocampus of APP/PS1 transgenic mice.

MicroRNA-142-5p (miR-142-5p) has been found to be dysregulated in several neurodegenerative disorders. However, little is known about the involvement of miR-142-5p in Alzheimer's disease (AD). Brain angiogenesis inhibitor 3 (BAI3), which belongs to the adhesion-G protein-coupled receptor subgroup, contributes to a variety of neuropsychiatric disorders.

Biosynthesis of polyphenols functionalized ZnO nanoparticles: Characterization and their effect on human pancreatic cancer cell line.

The present work investigate the green synthesis of zinc oxide nanoparticles (ZnO NPs) using Anacardium occidentale leaf extract by an eco-friendly method. ZnO NPs were synthesized by boiling the mixture of 10 ml of Anacardium occidentale leaf extract and 30 ml 0.1 M zinc nitrate (ZnNO) at 60 °C for 3 h.