Effect of the main constituents of Pistacia lentiscus leaves against the DPPH radical and xanthine oxidase: experimental and theoretical study.

The aim of this work is to study the content of phenolic compounds in leaves and their antioxidant effect. After extracting the phenolic compounds, fractionation by liquid/liquid partition with increasing polarity gives five extracts. Three of them (ButF, AqF and ButA) were found to have good antioxidant activity.

Multi optimized SVM classifiers for motor imagery left and right hand movement identification.

EEG signal can be a good alternative for disabled persons who cannot perform actions or perform them improperly. Brain computer interface (BCI) is an attractive technology which permits control and interaction with a computer or a machine using EEG signals. Brain task identification based on EEG signals is very difficult task and is still challenging researchers.

Breastfeeding for Primary Prevention of Stroke.

A recent review by Zhang et al. published in the "Journal of the National Medical Association" focused on the major and emerging strategies for the prevention of stroke. We would highlight the evolving role of breastfeeding as an efficient intervention in primary prevention of such cardiovascular disease, including in black women.

"3M": Migraine, Microbiota and Melatonin.

We read with deep interest the recent article published on "Medical Hypotheses" about migraine and associated gastrointestinal disorders. Beyond the exhaustive pathophysiological explanations, we would address some relevant points to the role of melatonin as well as the high potential of intestinal microbiota in such conditions.

Autism & Gluten: The Proof By Regression!

Investigators from different clinical and research centers from Paris, France studied the polymorphisms of the HLA class II loci in an autistic population. Through a case control design, they looked for the distribution of HLA class II alleles, genotypes and haplotypes in Autism Spectrum Disorders (ASD) patients meeting DSM-IV TR criteria versus healthy controls (HC).

Tracing the path of cancer initiation: the AA protein-based model for cancer genesis.

Background: Cancer is a defiant disease which cure is still far from being attained besides the colossal efforts and financial means deployed towards that end. The continuing setbacks encountered with today's arsenal of anti-cancer drugs and cancer therapy modalities; show the need for a radical approach in order to get to the root of the problem. And getting to the root of cancer initiation and development leads us to challenge the present dogmas surrounding the pathogenesis of this disease.

Ataxia in children: think about vitamin E deficiency ! (comment on: ataxia in children: early recognition and clinical evaluation).

A recent article from Pavone et al. published in the Italian Journal of Pediatrics entitled «Ataxia in children: early recognition and clinical evaluation» made an exhaustive overview of the large spectrum of pediatric ataxias. However, we would underline the importance of considering hereditary ataxia due to isolated vitamin E deficiency as a specific and treatable cause of child ataxia.

DNA Mutations May Not Be the Cause of Cancer.

Cancer is the most challenging disease of our time with increasing numbers of new cases each year, worldwide. Great achievements have been reached in cancer research through deep sequencing which helped define druggable targets. However, the still-evolving targeted therapy suffers resistance suggesting that DNA mutations considered as drivers may not have a role in tumor initiation.

Migraine, Celiac Disease and Intestinal Microbiota.

Investigators from four European tertiary care hospitals (in Paris, France; Milan, Udine and Perugia, Italy) performed a case-control study of children and adolescents aged 6 to 17 years diagnosed with primary headaches in the emergency department by a pediatric neurologist using the validated ICHD-3 criteria.

Bull Fertility and Its Relation with Density Gradient Selected Sperm.

Background: Sperm selection method is usually used to collect these cells for -assisted reproduction. Few studies reported the relationship of fertility and semen parameters after sperm selection; hence, the present study attempted to assess different semen parameters after post-thaw or sperm selection, using density gradient separation BoviPure®, to predict fertility.

Materials And Methods: In this experimental study, frozen semen quality of four Montbeliarde bulls were assessed after post-thaw (PT) or after sperm selection (SSp), using density gradient separation BoviPure®, to predict the fertility rate in vivo.

Physicochemical properties and biological activities of novel blend films using oxidized pectin/chitosan.

Pectin has been widely used in a variety of biomedical applications. In this study, it was modified with sodium periodate as an oxidant and characterized by physicochemical methods Periodate oxidation increased the contents of dialdehyde units and carboxyl groups in pectin, and a decrease in pectin viscosity was measured. The oxidization reaction led to a significant decrease in all values of molecular weight and size (Mn, Mw, [η] and Rh) as determined by size exclusion chromatography (SEC), which allowed the selection of the oxidized pectin to be added to chitosan.

Hemodialysis catheter-related infection: rates, risk factors and pathogens.

The main complication of central venous catheter (CVC) in hemodialysis is infection. Identifying CVC related infection (CVC-RI) risk factors and causative micro-organisms is important for setting prevention policies. There were no data regarding CVC-RI in hemodialysis in Algeria.

Identifying and Targeting the Cause of Cancer is Needed to Cure Cancer.

Cancer cells continue to challenge scientists and oncologists due to the phenomenon of resistance. Moreover, recurrence, as seen in many treated patients, shows that currently-used anti-cancer drugs are unable to prevent the development of new cancer cells harboring new mutations. The purpose of this paper is to try to answer some of the questions regarding why cancer arises and why evolution would naturally lead to the development of cancer.