2,208 results match your criteria: "Seth G. S. Medical College[Affiliation]"

Adolescent primary hyperparathyroidism.

Best Pract Res Clin Endocrinol Metab

January 2025

Department of Endocrinology, Seth G.S. Medical College and King Edward Memorial Hospital, Mumbai, India. Electronic address:

Adolescent primary hyperparathyroidism (PHPT) is a rare endocrine disorder bearing distinctions from the adult form. This review examines its unique aspects, focusing on clinical presentation, genetic etiologies, genotype-phenotype correlations, and therapeutic management. Adolescent PHPT often has a genetic basis, whether familial, syndromic, or apparently sporadic, and identifying the underlying genetic cause is important for patient care.

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Background: Traveller's health is one of the factors determining the success of his or her visit to the destination. The health aspects before, during and after travel are often neglected which may lead to untoward incidences during or after travel. Also, with the increase in national and international travel many emerging and re-emerging diseases are on the rise.

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Thiamine responsive megaloblastic anemia (TRMA), also known as Roger's syndrome, is an exceptionally rare autosomal recessive disorder stemming from mutations in the SLC19A2 gene responsible for encoding a thiamine carrier protein. This syndrome manifests as the classic triad of megaloblastic anemia, sensorineural hearing loss, and diabetes mellitus. Here, we present the case of a one-and-a-half-year-old male infant born to non-consanguineous parents in India, a region where TRMA cases are seldom reported.

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Background: Atrophy and fatty infiltration of the supraspinatus (SS) muscle are prognostic indicators of poor functional outcomes and higher retear rates after rotator cuff repair. While older patients, female patients, and those with massive and retracted rotator cuff tears are at a higher risk for these indicators, it is unclear whether tear characteristics, acromion morphology, and acromioclavicular (AC) joint arthritis affect SS atrophy in older patients with chronic shoulder pain.

Purpose: To investigate the multifactorial influences associated with SS atrophy in rotator cuff tears.

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White epidermoid cysts are rare intra-cranial lesions with an intrinsic brainstem location, though still rare. The location of the tumour poses radiological confusion and a therapeutic dilemma. Neuroimaging techniques like MRI with diffusion tensor imaging (DTI) in this case proved a useful tool in ruling out other pathologies at this location with certain morphologic similarities.

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Background And Objectives: Various ear, nose, and throat (ENT) conditions can result in vision loss. The purpose of this study is to identify the etiologies, presentations, and radiological findings associated with impaired vision in the context of ENT. Additionally, this article discusses management protocols, including optic nerve decompression and orbital decompression.

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Impact of diabetes mellitus on mortality in pulmonary hypertension: A systematic review and meta-analysis.

World J Crit Care Med

December 2024

Department of Research, Global Remote Research Scholar Program, Princeton Junction, Princeton, NJ 08550, United States.

Background: Pulmonary hypertension (PH) is a progressive disease characterized by endothelial dysfunction and vascular remodeling and is a leading cause of mortality worldwide. Although it is independently associated with multiple comorbidities, the impact of diabetes mellitus (DM) on mortality in patients with PH remains uncertain. To address this issue, we conducted a systematic review and meta-analysis to investigate the effect of DM on survival in patients with pulmonary hypertension.

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Mapping anti-diphtheria toxin antibody: a systematic review and meta-analysis with multi-level meta-regression.

Pathog Glob Health

December 2024

Center for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.

Diphtheria is a reemerging vaccine-preventable infection of public health concern. Pooled estimates of serum IgG anti-diphtheria antibody levels can assist in estimating the susceptible population. The objective was to estimate pooled estimate of protective IgG anti-diphtheria antibodies in population globally.

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Introduction: Undergraduate medical students often lack the soft skill of empathy which is considered as an important attribute for doctors. Hence, this study was conducted to improve the empathy skills among undergraduate students of a medical college in Kolkata.

Methods: A quasi-experimental study was conducted in the Rural Health Training Centre of a medical college in Kolkata among the undergraduate medical students during community medicine posting.

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Challenges and barriers in conducting school-based physical activity research: A narrative review.

J Family Med Prim Care

October 2024

Department of Cardiovascular and Respiratory Physiotherapy, Physiotherapy School and Center, Seth G.S Medical College, KEM Hospital, Parel, Mumbai, Maharashtra, India.

Physical activity (PA) is associated with numerous mental and physical health benefits. But it has been observed that young people and children frequently participate in low levels of PA, which is especially noticeable when they progress from primary to secondary school. Thus, in order to improve physical health among school-going children, different schools should put in place school-based PA intervention programs.

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Introduction: Differentiating pheochromocytomas from other adrenal masses based on computed tomography (CT) characteristics remains challenging, particularly in lipid-poor lesions with variable washout patterns. This study evaluated CT features for distinguishing pheochromocytomas in good and poor washout subcohorts.

Methods: We prospectively analyzed 72 patients with unilateral lipid-poor adrenal masses.

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Exploring sex toy use among 18-45-year-old Indian adults: insights from a nationwide online survey.

Lancet Reg Health Southeast Asia

January 2025

Department of Community Medicine, Government Medical College and Hospital, Nagpur - Ground Floor, College Building, Government Medical College and Hospital - Nagpur, Hanuman Nagar, Nagpur, Maharashtra, 440003, India.

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Recurrent spontaneous abortions (RSA) is defined as a loss of two or more consecutive clinically recognized pregnancies before the 20th week of gestation. In RSA, several causative maternal factors are known, but still, 50% of the cases remain unexplained. Evidence suggests that paternal factors are also equally important.

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Article Synopsis
  • Tuberculosis (TB) is a major global health issue, with extrapulmonary TB (EPTB) accounting for 15-20% of cases; diagnosing it is difficult due to nonspecific symptoms, especially in at-risk groups.
  • A case of a 25-year-old male with ear discharge and swelling led to imaging that revealed rare TB involvement in the parotid and mastoid regions, ultimately confirmed by microbiological testing showing Rifampicin-resistant mycobacteria.
  • The study highlights the need for high suspicion of TB in unusual infections, the importance of advanced imaging for diagnosis, and the necessity for microbiological confirmation to ensure effective and timely treatment.
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Background: Meningococcal disease remains an important public health problem globally. We assessed the non-inferiority and the lot-to-lot consistency of a pentavalent meningococcal ACYWX conjugate vaccine (NmCV-5; Serum Institute of India, Pune, India) versus a quadrivalent meningococcal ACWY conjugate vaccine (MenACWY-D) in healthy adults.

Methods: In this observer-blind, randomised, active-controlled, phase 2/3 study, healthy adults aged 18-85 years were recruited from nine hospitals across seven cities in India.

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A 42-year-old man, a known case of FGF23-dependent hypophosphatemia, underwent 68 Ga- DOTATATE PET-CT, which showed a somatostatin receptor-expressing lesion in the left arch of foramen magnum that was correlated on MRI as a soft tissue lesion measuring 2.2 × 1.3 cm.

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