[Concentrations of calcium and bone remodeling biomarkers in umbilical cord blood and urine of newborn infants during delivery].

Objective: To evaluate calcium, phosphorus, parathormone (PTH), osteocalcin, and alkaline phosphatase concentrations in cord blood, pyridinoline concentrations in urine, and the pyridinoline/creatinine ratio in order to indirectly assess late bone remodeling in the newborn by comparing concentrations of these substances with those in the mother during the third trimester and delivery.

Patients And Methods: Calcium, phosphorus, PTH, osteocalcin, and alkaline phosphatase levels in cord blood, pyridinolines in urine and the pyridinoline/creatinine ratio were evaluated in 38 healthy pregnant women during the last two months of pregnancy and during delivery. To determine concentrations of these substances, samples from vein umbilical cord blood were obtained immediately after birth and urine samples were obtained from the neonates within 24 hours of delivery.