491 results match your criteria: "Servicio de Neurología Hospital de Cruces[Affiliation]"

Introduction And Objectives: We report the results of the 2023 Spanish catheter ablation registry.

Methods: Procedural data were collected and incorporated into the REDCap platform by all participating centers through a specific form.

Results: There were 104 participating centers in 2023 compared with 103 in 2022.

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Cardiac resynchronization therapy with triple fusion using the SyncAV dynamic algorithm compared to conventionally optimized biventricular pacing: Results from the multicentric, randomized, double-blinded CRUSTY trial.

Heart Rhythm

December 2024

Arrhythmia Unit, Cardiology Department, Hospital Universitari Vall d'Hebron, Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Spain; Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain; CIBER de Enfermedades Cardiovasculares (CIBER-CV), Instituto de Salud Carlos III, Madrid, Spain.

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The Asociación Española de Pancreatología (AESPANC), Asociación Española de Gastroenterología (AEG), and Sociedad Española de Patología Digestiva (SEPD) have developed a consensus document on the standards and recommendations they consider essential for the organization of pancreas units (PUs) within gastroenterology services (GSs) in order to conduct their activities in an efficient, high-quality manner. The consensus document defines PUs and lays down standards relating to their organization, structure, service portfolio, processes, and teaching and research activities. Standards have been categorized as mandatory (requirements to be met to qualify for certification by the scientific societies responsible for the standards) or recommendations.

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Article Synopsis
  • MS is a significant cause of disability in young and middle-aged adults; existing clinical markers are not sensitive or specific enough for diagnosing and monitoring the disease.
  • After neuronal injury in MS, neurofilament light chains (NfL) are released into the cerebrospinal fluid and blood, suggesting they may serve as a useful biomarker for monitoring inflammation and neurodegeneration.
  • A study in Spain showed that blood-based NfL could improve diagnosis and treatment responses in MS, offering a safer and potentially less expensive alternative in clinical practice.
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Purpose: It is unclear whether preoperative serum uric acid (SUA) elevation may play a role in the development of acute kidney injury (AKI) associated with cardiac surgery (CSA-AKI). We conducted a cohort study to evaluate the influence of preoperative hyperuricemia on AKI in patients at high risk for developing SC-AKI.

Design: Multicenter prospective international cohort study.

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Update of the recommendations on the management of the SARS-CoV-2 coronavirus pandemic (COVID-19) in kidney transplant patients.

Nefrologia (Engl Ed)

December 2023

Unidad de Gestión Clínica de Nefrología, Hospital Regional Universitario de Málaga, Universidad de Málaga, Instituto Biomédico de Investigación de Málaga (IBIMA), RICORS2040 (RD21/0005/0012), Málaga, Spain.

SARS-CoV-2 infection (COVID-19) has had a significant impact on transplant activity in our country. Mortality and the risk of complications associated with COVID-19 in kidney transplant recipients (KT) were expected to be higher due to their immunosuppressed condition and the frequent associated comorbidities. Since the beginning of the pandemic in March 2020 we have rapidly improved our knowledge about the epidemiology, clinical features and management of COVID-19 post-transplant, resulting in a better prognosis for our patients.

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Introduction: Post transplant lymphoproliferative disorders (PTLD) are heterogeneous lymphoid proliferations in recipients of solid organs which seem to be related to Epstein Barr Virus (EBV). The use of antilymphocyte antibodies, EBV seronegativity in the recipient,acute rejection and CMV infection have been identified as classical risk factors.

Material Y Methods: We have studied in a retrospective observational study, the incidence of PTLD in a period of 22 years, its relationship with EBV, presence of classical risk factors and outcome in 21546 simple adult renal transplant recipients from cadaveric and living donors, transplanted in 21 hospitals from 1990 to 2009.

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The 2021 guidelines on the prevention of vascular disease (VD) in clinical practice published by the European Society of Cardiology (ESC) and supported by 13 other European scientific societies recognize the key role of screening for chronic kidney disease (CKD) in the prevention of VD. Vascular risk in CKD is categorized based on measurements of estimated glomerular filtration rate (eGFR) and urine albumin to creatinine ratio (ACR). Thus, moderate CKD is associated with a high vascular risk and severe CKD with a very high vascular risk requiring therapeutic action, and there is no need to apply other vascular risk scores when vascular risk is already very high due to CKD.

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Validity of CEEW equations for weight estimation in Spanish paediatric patients.

An Pediatr (Engl Ed)

March 2023

Biocruces Bizkaia Health Research Institute, Barakaldo, Spain; Facultad de Medicina y Enfermería, Universidad del País Vasco/Euskal Herriko Unibertsitatea, Leioa, Spain; Dirección de Enfermería, Hospital Santa Marina, Bilbao, Spain. Electronic address:

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Article Synopsis
  • The study focused on the use of intracoronary pressure wires in guiding treatment for patients with coronary artery disease, aiming to assess changes in diagnosis, treatment strategies, and clinical outcomes.
  • Involving 1,414 patients and observing 1,781 lesions, the study found significant changes in the extent of coronary disease and treatment plans, with over half of the patients experiencing adjustments after using the pressure wire.
  • The findings indicated that using the pressure wire was generally safe and led to a lower incidence of major adverse cardiovascular events (MACE), particularly when percutaneous coronary intervention (PCI) was the initial treatment strategy.
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Key Factors Associated With Pulmonary Sequelae in the Follow-Up of Critically Ill COVID-19 Patients.

Arch Bronconeumol

April 2023

Translational Research in Respiratory Medicine, University Hospital Arnau de Vilanova and Santa Maria, IRBLleida, Lleida, Spain; CIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain. Electronic address:

Article Synopsis
  • Critical COVID-19 survivors have a significant risk of respiratory issues, leading to a study that identifies factors linked to poor lung function and CT scan abnormalities in these patients.
  • The study involved 1,327 patients from 52 Spanish intensive care units, examining their health data at hospital admission and follow-up, which occurred around 3.57 months after discharge.
  • Results showed many patients had reduced lung capacity and CT scans revealed issues like pulmonary infiltrates and fibrosis, with age, chronic lung disease, and mechanical ventilation duration being key predictors of these complications.
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SARS-CoV-2 infection (COVID-19) has had a significant impact on transplant activity in our country. Mortality and the risk of complications associated with COVID-19 in kidney transplant recipients (KT) were expected to be higher due to their immunosuppressed condition and the frequent associated comorbidities. Since the beginning of the pandemic in March 2020 we have rapidly improved our knowledge about the epidemiology, clinical features and management of COVID-19 post-transplant, resulting in a better prognosis for our patients.

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Unlabelled: Tumor-necrosis-factor-α inhibitors (anti-TNF-α) are associated with an increased risk of tuberculosis (TB) disease, primarily due to reactivation of latent TB infection (LTBI). We assessed the performance of parallel LTBI screening with tuberculin skin test (TST) and QuantiFERON-TB Gold In-Tube assays (QFT-GIT) before anti-TNF-α treatment in children with immune-mediated inflammatory disorders in a low TB-burden setting. We conducted a multicenter cohort study involving 17 pediatric tertiary centers in Spain.

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Post-transplant diabetes mellitus and renal cell cancer after renal transplantation.

Nephrol Dial Transplant

May 2023

University of La Laguna, Faculty of Medicine, Instituto de Tecnologías Biomédicas (ITB), University of La Laguna. Tenerife, Spain.

Article Synopsis
  • Diabetes can be a risk factor for cancer, but there is limited research on how post-transplant diabetes mellitus (PTDM) influences cancer risk after organ transplants.
  • In a study of Spanish patients without diabetes before transplant, researchers found that PTDM did not generally increase cancer risk, but indicated a significant association with renal cell cancer (RCC).
  • The study suggests that patients with PTDM should be monitored closely for RCC due to their higher risk compared to those without PTDM.
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Genomic and phenotypic characterization of 404 individuals with neurodevelopmental disorders caused by CTNNB1 variants.

Genet Med

November 2022

Adelaide Medical School, The University of Adelaide, Adelaide, South Australia, Australia; Robinson Research Institute, The University of Adelaide, Adelaide, South Australia, Australia. Electronic address:

Article Synopsis
  • Germline loss-of-function variants in the CTNNB1 gene are linked to neurodevelopmental disorders that include spastic diplegia and visual issues, making them a common genetic cause of cerebral palsy (CP).
  • A study analyzed genetic data from 404 individuals with pathogenic CTNNB1 variants, including newly detailed phenotypes for 52 cases, to explore how these variants relate to CP and other traits.
  • Findings showed that individuals with CTNNB1 variants exhibited similar clinical features, suggesting that CP is part of the neurodevelopmental disorder spectrum rather than a separate condition; two specific variants were found to disrupt WNT signaling processes.
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Context/objective: No information is available regarding priorities for pediatric-onset spinal cord injury (SCI). This study described the Health and Life (H&L) domain priorities of youth with pediatric-onset SCI and their parents/caregivers living in Spain.

Design: A cross-sectional survey.

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Background: The clinical heterogeneity of COVID-19 suggests the existence of different phenotypes with prognostic implications. We aimed to analyze comorbidity patterns in critically ill COVID-19 patients and assess their impact on in-hospital outcomes, response to treatment and sequelae.

Methods: Multicenter prospective/retrospective observational study in intensive care units of 55 Spanish hospitals.

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Background: Previous studies comparing immigrant ethnic groups and native patients with IBD have yielded clinical and phenotypic differences. To date, no study has focused on the immigrant IBD population in Spain.

Methods: Prospective, observational, multicenter study comparing cohorts of IBD patients from ENEIDA-registry who were born outside Spain with a cohort of native patients.

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Introduction And Objectives: Transaxillary access (TXA) has become the most widely used alternative to transfemoral access (TFA) in patients undergoing transcatheter aortic valve implantation (TAVI). The aim of this study was to compare total in-hospital and 30-day mortality in patients included in the Spanish TAVI registry who were treated by TXA or TFA access.

Methods: We analyzed data from patients treated with TXA or TFA and who were included in the TAVI Spanish registry.

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Aim: to communicate the home parenteral nutrition (HPN) data obtained from the HPN registry of the NADYA-SENPE group (www.nadya-senpe.com) for the year 2019.

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Improved collection of hematopoietic stem cells and progenitors from Fanconi anemia patients for gene therapy purposes.

Mol Ther Methods Clin Dev

September 2021

Centro de Investigación Biomédica en Red de Enfermedades Raras, 28029 Madrid, Spain.

Difficulties in the collection of hematopoietic stem and progenitor cells (HSPCs) from Fanconi anemia (FA) patients have limited the gene therapy in this disease. We have investigated (ClinicalTrials.gov, NCT02931071) the safety and efficacy of filgrastim and plerixafor for mobilization of HSPCs and collection by leukapheresis in FA patients.

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Objective: To assess the epidemiology and outcome at discharge of cancer patients requiring admission to the Intensive Care Unit (ICU).

Design: A descriptive observational study was made of data from the ENVIN-HELICS registry, combined with specifically compiled variables. Comparisons were made between patients with and without neoplastic disease, and groups of cancer patients with a poorer outcome were identified.

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Azole resistance survey on clinical Aspergillus fumigatus isolates in Spain.

Clin Microbiol Infect

August 2021

Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid, Spain; Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain; CIBER Enfermedades Respiratorias-CIBERES (CB06/06/0058), Madrid, Spain. Electronic address:

Objectives: We aimed to assess the percentage of azole resistance in Aspergillus fumigatus in Spain.

Methods: Thirty participating Spanish hospitals stored all morphologically identified A. fumigatus sensu lato clinical isolates-regardless their clinical significance-from 15 February to 14 May 2019.

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