Clinical experience of cefiderocol.

Infections by antibiotic-resistant microorganisms could be considered a "stealth pandemic" that we fight daily in most hospitals. Some estimates suggest that today 700,000 deaths per year can be attributed to antimicrobial resistance. By the year 2050, it is estimated that this will increase to ten million deaths per year as a result of infections by multidrug-resistant microorganisms.

Double treatment with paricalcitol-associated calcifediol and cardiovascular risk biomarkers in haemodialysis.

Background: The deficit of 25-hydroxyvitamin D (25OHD) associated with secondary hyperparathyroidism (SHPT) is a frequent finding in chronic kidney disease (CKD) patients on haemodialysis (HD). These events are associated with increased morbidity and mortality rates of cardiovascular (CV) origin. Adequate 25OHD serum levels as well as the use of selective vitamin D receptor activators (VDRA) have been shown to have beneficial and independent effects on bone mineral metabolism and cardiovascular risk.

[Assessment of cerebral blood flow in patients with eating disorders in the acute clinical phase using Tc99m-HMPAO spect].

Objective: To assess the status of cerebral perfusion in patients with eating disorders (ED) in the acute phase of the disease.

Materials And Methods: Seventeen patients, with a mean age of 22 years, diagnosed with ED according to DSM-III-R (Diagnostic and Statistical Manual of Mental Disorders) criteria and under close clinical monitoring were studied in the initial acute phase of their disease. Brain SPECT with 15 mCi of Tc99m HMPAO was performed on all patients and assessed using visual and semi-quantitative analysis.

[Bone scintigraphy in Erdheim-Chester disease].

Erdheim-Chester disease (ECD) is a rare disorder with fewer than 80 cases reported in the world. It consists of a non-Langerhans' cell histiocytosis that usually presents as pain due to bone involvement; however, the prognosis is marked by extraskeletal involvement. Although the final diagnosis needs an anatomophatologic study (normally through a bone biopsy), radiologic and scintigraphic findings are quasi pathognomonic.

[Risk factors and stroke among patients of different ages].

Objective: To determine the frequency of cardiovascular risk factors in patients of different ages with ischemic cerebrovascular accident.Patients and methods. Descriptive, retrospective study of 1,077 patients with stroke or transient ischemic attack.

[Pre and perioperative factors determining early in-hospital mortality in patients over 75 years of age undergoing cardiac surgery].

Introduction And Objectives: To know the in-hospital morbidity and mortality and the related factors in patients over 75 years old undergoing cardiac surgery.

Patients And Methods: A retrospective analysis was carried out in 252 out of 2043 consecutive patients (129 female, 123 male) over 75 years of age (mean age 77.8 years; range 75 to 89 years) undergoing open heart surgery from january 1, 1994 to november 30, 1997.