Exploring Fungal Biodiversity in Crop Rotation Systems: Impact of Soil Fertility and Winter Wheat Cropping.

This study investigated soil fungal biodiversity in wheat-based crop rotation systems on Chernozem soil within the Pannonian Basin, focusing on the effects of tillage, crop rotation, and soil properties. Over three years, soil samples from ten plots were analyzed, revealing significant fungal diversity with Shannon-Wiener diversity indices ranging from 1.90 in monoculture systems to 2.

Lipid Biomarkers in Urban Soils of the Alluvial Area near Sava River, Belgrade, Serbia.

This study focused on the investigation of soil samples from the alluvial zone of the Sava River, located near the heating plant in New Belgrade, Serbia. Using gas chromatography with flame ionization detection (GC-FID), a broad range of alkanes, including linear -alkanes (C to C) and isoprenoids, was analyzed in all samples. The obtained datasets were effectively made simpler by applying multivariate statistical analysis.

Dapsone Alters Phenotypical and Functional Properties of Human Neutrophils In Vitro.

Dapsone is a sulfone used in treating inflammatory skin conditions. Despite its widespread dermatological use, the pharmacological actions of dapsone remain poorly understood. Here, we examined how different aspects of neutrophil functions are affected by dapsone.

Ozone/Thiosulfate-Assisted Leaching of Cu and Au from Old Flotation Tailings.

The growing demand for metal production promotes the search for alternative sources and novel modalities in metallurgy. Flotation tailings are an important secondary mineral resource; however, they might pose a potential environmental threat due to containing toxic metals. Therefore, proper leaching reagent selection is required.

Food resilience and adaptation on the move: the importance of fostering studies on the Romani local knowledge systems.

This analysis explores the food local knowledge of the Romani people in Italy, one of the most significant and historically marginalised ethnic groups in Europe. Despite their centuries-long presence across European countries, the Romani community's culinary and herbal practices have often been overlooked. A preliminary study on Romani domestic food and home (plant) remedies was conducted via 106 interviews in Turin, Rome, and Naples during the past fifteen years among urban Romani community members (who migrated to Italy from Romania and Serbia approximately three decades ago).

Prenatal diagnosis of chromothripsis causing complex chromosomal rearrangement involving chromosomes 5, 7 and 11 leading to TWIST1 deletion and Saethre-Chotzen syndrome.

Objective: Prenatal detection of complex chromosomal rearrangements (CCR) is extremely rare, but is of great clinical importance, since CCR can be causative of different congenital disorders. We present an exceptionally rare case of prenatally diagnosed Saethre-Chotzen syndrome (SCS) rising as a consequence of chromothripsis involving chromosomes 5, 7 and 11 and deletion of TWIST1 gene.

Case Report: Brachycephaly, hypertelorism, flat face, micrognathia, relative macroglossia and small posterior fossa were noted on ultrasound examination at 28th gestational week.

Enhancing lumpy skin disease control: Effective competitive and indirect ELISAs for serological surveillance.

Lumpy skin disease (LSD), caused by the LSD virus (LSDV) from the Capripoxvirus genus, affects cattle, water buffalo, and wild bovines, leading to significant economic losses. Characterised by fever, skin nodules, and mucosal lesions, LSD raises global concerns due to vector-borne transmission. The World Organisation for Animal Health (WOAH) classifies LSD as a notifiable disease, emphasising the need for rapid diagnostic methods for timely disease confirmation and control.

Multiomics dissection of human RAG deficiency reveals distinctive patterns of immune dysregulation but a common inflammatory signature.

Human recombination-activating gene (RAG) deficiency can manifest with distinct clinical and immunological phenotypes. By applying a multiomics approach to a large group of -mutated patients, we aimed at characterizing the immunopathology associated with each phenotype. Although defective T and B cell development is common to all phenotypes, patients with hypomorphic variants can generate T and B cells with signatures of immune dysregulation and produce autoantibodies to a broad range of self-antigens, including type I interferons.

Biochar in the Remediation of Organic Pollutants in Water: A Review of Polycyclic Aromatic Hydrocarbon and Pesticide Removal.

This review explores biochar's potential as a sustainable and cost-effective solution for remediating organic pollutants, particularly polycyclic aromatic hydrocarbons (PAHs) and pesticides, in water. Biochar, a carbon-rich material produced from biomass pyrolysis, has demonstrated adsorption efficiencies exceeding 90% under optimal conditions, depending on the feedstock type, pyrolysis temperature, and functionalization. High surface area (up to 1500 m/g), porosity, and modifiable surface functional groups make biochar effective in adsorbing a wide range of contaminants, including toxic metals, organic pollutants, and nutrients.

Functional and Lateral Asymmetry of the Knee Joint Muscles Measured Using Tensiomyography (TMG) in Professional Football Players of Different Playing Positions.

: The aim of this study is to determine whether different playing positions in football influence muscle asymmetry, which is a common cause of injuries in football. This study aimed to determine the difference in the functional and lateral asymmetry of the knee joint muscles measured using tensiomyography (TMG) between football players of different playing positions. : This study included 52 professional football players (25.

Status of Sepsis Care in European Hospitals: Results from an International Cross-Sectional Survey.

Rationale: Early detection, standardized therapy, adequate infrastructure and strategies for quality improvement should constitute essential components of every hospital's sepsis plan.

Objectives: To investigate the extent to which recommendations from the sepsis guidelines are implemented and the availability of infrastructure for the care of patients with sepsis in acute hospitals.

Methods: A multidisciplinary cross-sectional questionnaire was used to investigate sepsis care in hospitals.

Sound and Alzheimer's Disease-From Harmful Noise to Beneficial Soundscape Augmentation and Music Therapy.

Exposure to sound energy may be a risk factor or a therapeutic intervention for Alzheimer's disease (AD). On one hand, noise has a harmful effect on people with AD by contributing to hearing loss, sleep disturbance, oxidative stress, inflammation, and excitotoxicity. But on the other hand, clinical trials and nursing home interventions with soundscape augmentation involving natural sounds have shown promising results in alleviating psychophysiological symptoms in people with AD.

Recycling honey bee drone brood for sustainable beekeeping.

Pollination by insects is vital for global agriculture, with honey bees (Apis mellifera L.) being the most important pollinators. Honey bees are exposed to numerous stressors, including disease, pesticides, and inadequate nutrition, resulting in significant colony losses.

Gene Polymorphisms are Associated With Clinical and Biochemical Parameters in COVID-19 Patients in Serbian Population.

The hypoxia-inducible factor-1 alpha (HIF-1 alpha) is a major regulator of adaptive response to hypoxia, common in patients with severe coronavirus disease 2019 (COVID-19). In addition, HIF-1 alpha regulates the expression of the most important proteins necessary for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection of cells. The study included 129 hospitalized COVID-19 patients.

Immune Cell-Based versus Albumin-Based Ratios as Outcome Predictors in Critically Ill COVID-19 Patients.

Purpose: The aim of the retrospective, single-center study was to assess the prognostic value of immune cell-based and albumin-based ratios regarding lethal outcome in critically ill COVID-19 patients.

Patients And Methods: We analyzed 612 adult critically ill COVID-19 patients admitted to the intensive care unit (ICU) between April 2020 and November 2022. Blood measurement on admission to the ICU encompassed complete blood count (CBC), IL-6, C-reactive protein (CRP), albumin, lactate, lactate dehydrogenase (LDH), serum bicarbonate, arterial base deficit/excess (BD/E), and D-dimer.

Antioxidant Responses in Chromium-Stressed Maize as Influenced by Foliar and Root Applications of Fulvic Acid.

Maize (Zea mays L.) faces significant challenges to its growth and productivity from heavy metal stress, particularly Chromium (Cr) stress, which induces reactive oxygen species (ROS) generation and damages photosynthetic tissues. This study aimed to investigate the effects of fulvic acid (FA) application, via foliar spray or root irrigation, on mitigating chromium stress in maize by evaluating its impact on antioxidant activity and growth parameters.

When conventional approach in toxicity assays falls short for nanomedicines: a case study with nanoemulsions.

The aim of this study was to assess the critical quality attributes of parenteral nanoemulsion formulations by measuring several physicochemical parameters and linking them to their in vitro performance, illustrating how simplistic and routinely used approaches are insufficient for understanding a potential nanomedicine. Physicochemical characterization should encompass size and size distribution through at least two orthogonal techniques, such as dynamic light scattering (DLS) and electron microscopy, with added value from analytical ultracentrifugation. In vitro toxicity assessment was performed using three different assays to determine mitochondrial activity (WST-1), membrane integrity (lactate dehydrogenase release (LDH) assay), and cell viability (propidium iodide (PI) staining).

Clinical characteristics, management, and malignancy rate of oral lichen planus: a European multicenter study.

Introduction: Oral lichen planus (OLP) is a chronic inflammatory mucocutaneous condition that includes a spectrum of oral clinical manifestations ranging from mild painless white lesions to painful erosions and ulcers. The purpose of this European multicenter study is to describe the general characteristics of OLP lesions, the clinical and histopathological diagnosis, and the management of OLP at different European Oral Medicine and Maxillofacial Surgery centers, in order to minimize selections biases and provide information about the current trends in the treatment of OLP across Europe.

Materials And Methods: Data and histopathological records of patients with OLP were retrospectives revised and only those patients that fulfilled the diagnostic criteria from the 2016 position paper by American Academy of Oral and Maxillofacial Pathology were included.

Differentiated effects and mechanisms of N-, P-, S-, and Fe-modified biochar materials for remediating Cd- and Pb-contaminated calcareous soil.

To investigate the remediation effects of various modified biochar materials derived from different impregnation agents on Cd- and Pb-contaminated calcareous soil, nitrogen (N-), phosphorus (P-), sulfur (S-), and iron (Fe-) modified biochar materials (NBC, PBC, SBC, FBC) were fabricated through the impregnation-pyrolysis method and employed to immobilize Pb and Cd in the calcareous soil. The characterization results showed that NBC exhibited an uneven pore size distribution and increased aromaticity, while PBC and SBC had increased pH and ash content. Pot experiments demonstrated significantly different effects of various modified biochar materials on soil immobilization and plant uptake of Cd and Pb.

Creatine Intake Is Not Associated With Elevated Circulating Cystatin C Levels in Individuals With and Without Kidney Dysfunction in the General Population.

Objective: The potential adverse effects of dietary creatine on kidney health are rarely addressed at the population level, particularly in individuals with preexisting kidney disease. This study aimed to evaluate the association between dietary creatine intake and serum cystatin C levels in participants with and without kidney failure, utilizing data from the 1999-2001 National Health and Nutrition Examination Survey (NHANES) round.

Method: A total of 4969 individuals (50.

Paired nerve stimulation with selective compensation effect.

Background: In this study we investigate the selective compensation of paired peripheral nerves in healthy humans, focusing on distinct axonal conduction velocities in different fibre types. Using paired associative stimulation (PAS) with adjustable parameters, we aimed to modulate and compensate for neuronal activity along the median nerve.

Methods: Six healthy volunteers (3 male, 3 female, aged: 22-49) participated in the current study.

Representations of in vitro fertilization in the first cycle of IVF in women.

Introduction: Women typically experience more intense stress related to infertility compared to men, which is partly connected to the importance that motherhood and parenthood have for women in most societies. Considering the dominance of pronatalism in the majority of cultures, it is not surprising that women, who are most often considered responsible for reproduction, suffer greater social and psychological pressure due to infertility.

Method: The study employs a social constructionist framework to explore how women facing infertility construct their notions of their first IVF treatment.