Goat's Milk Powder Enriched with Red ( L.) and Black ( Murray) Goji Berry Extracts: Chemical Characterization, Antioxidant Properties, and Prebiotic Activity.

The current trend in food innovations includes developing products containing plant ingredients or extracts rich in bioactive compounds. This study aimed to prepare and characterize skimmed thermally treated goat's milk powders enriched with lyophilized fruit extracts of Murray (GMLR) and L. (GMLB).

Technological and Functional Characteristics of Lactic Acid Bacteria from Traditional Serbian Cheeses.

Owing to the rich diversity of lactic acid bacteria (LAB) microbiota, traditional Serbian white-brined cheeses can serve as a valuable source of LAB strains with promising technological and functional properties. This study aimed to identify potential candidates for developing commercial bacterial cultures, which could be used to produce cheese with distinct sensory qualities and added value as a functional food product. A total of 83 LAB isolates were tested for their ability to grow under different salt concentrations and temperatures; their acidifying, proteolytic, and lipolytic activities; and their production of diacetyl and exopolysaccharides (EPSs).

Impact of Chocolate Cadmium on Vulnerable Populations in Serbia.

Chocolate is one of the most popular and widely consumed confectionery products. However, elevated cadmium (Cd) content in this commodity threatens food safety and human health. It is crucial to monitor the presence of Cd in chocolate and to evaluate its associated health risks.

Theoretical Study of Antioxidant and Prooxidant Potency of Protocatechuic Aldehyde.

In this study, the antioxidant and prooxidant potency of protocatechuic aldehyde (PCA) was evaluated using density functional theory (DFT). The potency of direct scavenging of hydroperoxyl (HOO) and lipid peroxyl radicals (modeled by vinyl peroxyl, HC=CHOO) involved in lipid peroxidation was estimated. The repair of oxidative damage in biomolecules (lipids, proteins and nucleic acids) and the prooxidant ability of PCA phenoxyl radicals were considered.

Oxidative Homeostasis in Follicular Fluid and Embryo Quality-A Pilot Study.

The objective of this study was to measure the different redox biomarker levels within the follicular fluid (FF) and evaluate correlations with embryo quality using the one follicle-one oocyte/embryo approach. The prospective study included 54 women (average age 34.6 ± 3.

You Win Some, You Lose Some: Modifying the Molecular Periphery of Nitrofuran-Tagged Diazaspirooctane Reshapes Its Antibacterial Activity Profile.

The use of the concept of privileged structures significantly accelerates the search for new leads and their optimization. 6-(methylsulfonyl)-8-(4-methyl-4-1,2,4-triazol-3-yl)-2-(5-nitro-2-furoyl)-2,6-diazaspiro[3.4]octane has been identified as a lead, with MICs of 0.

Alpinetin Exhibits Antioxidant and Anti-Inflammatory Effects in C57BL/6 Mice with Alcoholic Liver Disease Induced by the Lieber-DeCarli Ethanol Liquid Diet.

Alcohol-associated liver disease (ALD) is a common non-communicable chronic liver disease characterized by a spectrum of conditions ranging from steatosis and alcohol-associated steatohepatitis (AH) to fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). The pathogenesis of ALD involves a complex interplay of various molecular, biochemical, genetic, epigenetic, and environmental factors. While the mechanisms are well studied, therapeutic options remain limited.

Dual-Double Stem Cell Ovarian Therapy: A Comprehensive Approach in Regenerative Medicine.

Dual-double stem cell therapy, which integrates mesenchymal stem cells (MSCs) and hematopoietic stem cells (HSCs), represents a cutting-edge approach in regenerative medicine, particularly for conditions such as ovarian decline, premature ovarian insufficiency (POI), and induced ovarian failure. This therapy leverages the unique properties of MSCs and HSCs, enhancing tissue repair, immune modulation, and overall regenerative outcomes. MSCs, known for their ability to differentiate into various cell types, provide a supportive microenvironment and secrete bioactive molecules that promote angiogenesis and reduce inflammation.

Herbal Waste from Filter-Tea Production as Eco-Friendly Ash for Sustainable Natural Rubber Composites.

Herbal dust, a waste byproduct from filter-tea production, was annealed to form ash that can be incorporated into natural rubber as an eco-friendly filler. Three types of herbal dust ash (HDA), green tea, hibiscus, and lemon balm, were added at two different contents, 2.5 and 5 phr, into the rubber compound, while the content of carbon black, as a filler, was maintained at 50 phr in all samples.

Greenhouse Gas Emissions from Molten Fluoride Electrolysis Composed of Raw and Magnet Recycling Derived Oxides: A Comparative Study.

In situ measurements of the chemical identity and quantity of anode gases during electrochemical measurements and rare earth (RE) electrolysis from fluoride-based molten salts composed of different kinds of rare earth oxides (REOs) were performed using FTIR spectrometry. Linear sweep voltammetry (LSV) was carried out to characterize oxidation processes and determine the anodic effect from NdF + PrF + LiF + REO melt. RE complex formation and subsequent reactions on the GC anode surface were discussed to understand the formation pathways of CO/CO and perfluorocarbon gases (PFC), mainly CF and CF.

Effects of Beech Wood Surface Treatment with Polyethylenimine Solution Prior to Finishing with Water-Based Coating.

The surfaces of beech wood samples were treated with polyethylenimine (PEI) solutions at three different concentrations-0.5%, 1% and 2%-and two molecular weights-low molecular weight (LMW) and high molecular weight (HMW). The effects of PEI surface treatment of wood were characterized by FT-IR spectroscopy, the penetration depth of PEI (EPI fluorescence spectroscopy), the bonding position of PEI (by SEM), the wetting and surface energy, and the water uptake.

Phytochemical Characterisation of Species: Unveiling Flavonoid Profiles Related to Ploidy and Hybrid Origin.

The genetic, morphological and taxonomic diversity of the genus is due to homoploid and polyploid hybridisation, autopolyploidy and apomixis, which also influence the production and diversity of secondary metabolites, especially flavonoids. The aim of this study was to investigate the relationships and variations of flavonoids in terms of hybrid origin and ploidy level between the parental species and their hybrid derivatives. The sampling design included leaf material of the following accessions from ten natural localities: parental taxa (di-, tri- and tetraploids of ; diploid and ) and their di-, tri- and tetraploid hybrid derivatives from crosses of × (subg.

Exploring Fungal Biodiversity in Crop Rotation Systems: Impact of Soil Fertility and Winter Wheat Cropping.

This study investigated soil fungal biodiversity in wheat-based crop rotation systems on Chernozem soil within the Pannonian Basin, focusing on the effects of tillage, crop rotation, and soil properties. Over three years, soil samples from ten plots were analyzed, revealing significant fungal diversity with Shannon-Wiener diversity indices ranging from 1.90 in monoculture systems to 2.

Lipid Biomarkers in Urban Soils of the Alluvial Area near Sava River, Belgrade, Serbia.

This study focused on the investigation of soil samples from the alluvial zone of the Sava River, located near the heating plant in New Belgrade, Serbia. Using gas chromatography with flame ionization detection (GC-FID), a broad range of alkanes, including linear -alkanes (C to C) and isoprenoids, was analyzed in all samples. The obtained datasets were effectively made simpler by applying multivariate statistical analysis.

Dapsone Alters Phenotypical and Functional Properties of Human Neutrophils In Vitro.

Dapsone is a sulfone used in treating inflammatory skin conditions. Despite its widespread dermatological use, the pharmacological actions of dapsone remain poorly understood. Here, we examined how different aspects of neutrophil functions are affected by dapsone.

Ozone/Thiosulfate-Assisted Leaching of Cu and Au from Old Flotation Tailings.

The growing demand for metal production promotes the search for alternative sources and novel modalities in metallurgy. Flotation tailings are an important secondary mineral resource; however, they might pose a potential environmental threat due to containing toxic metals. Therefore, proper leaching reagent selection is required.

Food resilience and adaptation on the move: the importance of fostering studies on the Romani local knowledge systems.

This analysis explores the food local knowledge of the Romani people in Italy, one of the most significant and historically marginalised ethnic groups in Europe. Despite their centuries-long presence across European countries, the Romani community's culinary and herbal practices have often been overlooked. A preliminary study on Romani domestic food and home (plant) remedies was conducted via 106 interviews in Turin, Rome, and Naples during the past fifteen years among urban Romani community members (who migrated to Italy from Romania and Serbia approximately three decades ago).

Prenatal diagnosis of chromothripsis causing complex chromosomal rearrangement involving chromosomes 5, 7 and 11 leading to TWIST1 deletion and Saethre-Chotzen syndrome.

Objective: Prenatal detection of complex chromosomal rearrangements (CCR) is extremely rare, but is of great clinical importance, since CCR can be causative of different congenital disorders. We present an exceptionally rare case of prenatally diagnosed Saethre-Chotzen syndrome (SCS) rising as a consequence of chromothripsis involving chromosomes 5, 7 and 11 and deletion of TWIST1 gene.

Case Report: Brachycephaly, hypertelorism, flat face, micrognathia, relative macroglossia and small posterior fossa were noted on ultrasound examination at 28th gestational week.

Enhancing lumpy skin disease control: Effective competitive and indirect ELISAs for serological surveillance.

Lumpy skin disease (LSD), caused by the LSD virus (LSDV) from the Capripoxvirus genus, affects cattle, water buffalo, and wild bovines, leading to significant economic losses. Characterised by fever, skin nodules, and mucosal lesions, LSD raises global concerns due to vector-borne transmission. The World Organisation for Animal Health (WOAH) classifies LSD as a notifiable disease, emphasising the need for rapid diagnostic methods for timely disease confirmation and control.

Multiomics dissection of human RAG deficiency reveals distinctive patterns of immune dysregulation but a common inflammatory signature.

Human recombination-activating gene (RAG) deficiency can manifest with distinct clinical and immunological phenotypes. By applying a multiomics approach to a large group of -mutated patients, we aimed at characterizing the immunopathology associated with each phenotype. Although defective T and B cell development is common to all phenotypes, patients with hypomorphic variants can generate T and B cells with signatures of immune dysregulation and produce autoantibodies to a broad range of self-antigens, including type I interferons.

Biochar in the Remediation of Organic Pollutants in Water: A Review of Polycyclic Aromatic Hydrocarbon and Pesticide Removal.

This review explores biochar's potential as a sustainable and cost-effective solution for remediating organic pollutants, particularly polycyclic aromatic hydrocarbons (PAHs) and pesticides, in water. Biochar, a carbon-rich material produced from biomass pyrolysis, has demonstrated adsorption efficiencies exceeding 90% under optimal conditions, depending on the feedstock type, pyrolysis temperature, and functionalization. High surface area (up to 1500 m/g), porosity, and modifiable surface functional groups make biochar effective in adsorbing a wide range of contaminants, including toxic metals, organic pollutants, and nutrients.

Functional and Lateral Asymmetry of the Knee Joint Muscles Measured Using Tensiomyography (TMG) in Professional Football Players of Different Playing Positions.

: The aim of this study is to determine whether different playing positions in football influence muscle asymmetry, which is a common cause of injuries in football. This study aimed to determine the difference in the functional and lateral asymmetry of the knee joint muscles measured using tensiomyography (TMG) between football players of different playing positions. : This study included 52 professional football players (25.