77 results match your criteria: "Sense Innovation and Research Center.[Affiliation]"

Dynamic X-ray Microtomography vs. Laser-Doppler Vibrometry: A Comparative Study.

J Assoc Res Otolaryngol

January 2025

Department of Otorhinolaryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, University of Bern, 3010, Freiburgstrasse, Bern, Switzerland.

Purpose: There are challenges in understanding the biomechanics of the human middle ear, and established methods for studying this system show significant limitations. In this study, we evaluate a novel dynamic imaging technique based on synchrotron X-ray microtomography designed to assess the biomechanical properties of the human middle ear by comparing it to laser-Doppler vibrometry (LDV).

Methods: We examined three fresh-frozen temporal bones (TB), two donated by white males and one by a Black female, using dynamic synchrotron-based X-ray microtomography for 256 and 512 Hz, stimulated at 110 dB and 120 dB sound pressure level (SPL).

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Intermodulation frequencies reveal common neural assemblies integrating facial and vocal fearful expressions.

Cortex

December 2024

Institute of Research in Psychology (IPSY) & Institute of Neuroscience (IoNS), Louvain Bionics Center, University of Louvain (UCLouvain), Louvain-la-Neuve, Belgium; School of Health Sciences, HES-SO Valais-Wallis, The Sense Innovation and Research Center, Lausanne & Sion, Switzerland. Electronic address:

Effective social communication depends on the integration of emotional expressions coming from the face and the voice. Although there are consistent reports on how seeing and hearing emotion expressions can be automatically integrated, direct signatures of multisensory integration in the human brain remain elusive. Here we implemented a multi-input electroencephalographic (EEG) frequency tagging paradigm to investigate neural populations integrating facial and vocal fearful expressions.

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Causality is a fundamental part of the scientific endeavor to understand the world. Unfortunately, causality is still taboo in much of psychology and social science. Motivated by a growing number of recommendations for the importance of adopting causal approaches to research, we reformulate the typical approach to research in psychology to harmonize inevitably causal theories with the rest of the research pipeline.

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Article Synopsis
  • Climate change is increasing extreme weather events, which can impact animal social structures and affect disease spread.
  • By studying rhesus macaques before and after a hurricane, research shows that disease transmission rates can double for up to 5 years post-disaster.
  • The hurricane changed how infection risk is spread within the population, highlighting that natural disasters not only threaten wildlife health but also pose risks of disease spilling over to humans.
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Unlabelled: Early diagnosis of Alzheimer's disease (AD) and mild cognitive impairment (MCI) is crucial to prevent their progression. In this study, we proposed the analysis of magnetic resonance imaging (MRI) based on features including; hippocampus (HC) area size, HC grayscale statistics and texture features (mean, standard deviation, skewness, kurtosis, contrast, correlation, energy, homogeneity, entropy), lateral ventricle (LV) area size, gray matter area size, white matter area size, cerebrospinal fluid area size, patient age, weight, and cognitive score. Five machine learning classifiers; K-nearest neighborhood (KNN), support vector machine (SVM), random forest (RF), decision tree (DT), and multi-layer perception (MLP) were used to distinguish between groups: cognitively normal (CN) vs AD, early MCI (EMCI) vs late MCI (LMCI), CN vs EMCI, CN vs LMCI, AD vs EMCI, and AD vs LMCI.

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Article Synopsis
  • Geometric optical illusions (GOIs) highlight mismatches between what we see and the actual physical stimuli, allowing researchers to explore how sensation and perception interact.
  • A study conducted with 30 adults revealed that different physical properties of GOIs have varying effects on perceptual biases, and these effects can interact in complex ways.
  • By combining psychophysics with computational modeling of the primary visual cortex, the researchers found that certain adjustments in neural parameters could replicate human perceptual biases, suggesting that different physical attributes work together to create a GOI and offering insights into the mechanisms behind perception.
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The computational perspective: A catalyst for research questions in cognitive neuroscience?

Neurosci Biobehav Rev

November 2024

Laboratory of Psychophysics, Brain Mind Institute, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland; The Radiology Department, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland; The Sense Innovation and Research Center, Lausanne and Sion, Lausanne, Switzerland.

Where do novel research questions come from? We suggest that identifying key computational problems and comparing solutions across domains can be one source. We exemplify this by looking at perception and action and outline how findings from one domain may generate novel research avenues in the other.

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Advancements in neural network approaches have enhanced the effectiveness of surface Electromyography (sEMG)-based hand gesture recognition when measuring muscle activity. However, current deep learning architectures struggle to achieve good generalization and robustness, often demanding significant computational resources. The goal of this paper was to develop a robust model that can quickly adapt to new users using Transfer Learning.

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In their study, Stavropoulos et al. (2023) capitalized on supervised machine learning and a longitudinal design and reported that the User-Avatar Bond could be accurately employed to detect Gaming Disorder (GD) risk in a community sample of gamers. The authors suggested that the User-Avatar Bond is a "digital phenotype" that could be used as a diagnostic indicator for GD risk.

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Spectral tuning and after-effects in neural entrainment.

Behav Brain Funct

November 2024

Laboratory of Psychophysics, Brain Mind Institute, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.

Neural entrainment has become a popular technique to non-invasively manipulate brain rhythms via external, periodic stimulation. However, there is still debate regarding its underlying mechanisms and effects on brain activity. Here, we used EEG recordings during a visual entrainment paradigm to assess characteristic changes in the spectral content of EEG signals due to entrainment.

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Most researchers agree that some stages of object recognition can proceed implicitly. Implicit recognition occurs when an object is automatically and unintentionally encoded and represented in the brain even though the object is irrelevant to the current task. No consensus has been reached as to what level of semantic abstraction processing can go implicitly.

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Conscious experiences during non-rapid eye movement sleep parasomnias.

Neurosci Biobehav Rev

December 2024

Minnesota Regional Sleep Disorders Center, Departments of Psychiatry, Hennepin County Medical Center,  USA; University of Minnesota Medical School, Minneapolis, MN, USA.

Disorders of Arousal (DOA) are non-rapid eye movement (NREM) parasomnias traditionally regarded as unconscious states. However, recent research challenges this assumption. This narrative review aims to explore the presence and qualitative features of conscious experiences in patients with DOA during their episodes.

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How visual experience shapes body representation.

Cognition

January 2025

Institute of Neuroscience (IoNS), Université Catholique de Louvain, Belgium; Institute for Research in Psychological Sciences (IPSY), Université Catholique de Louvain, Belgium; HES-SO Valais-Wallis, The Sense Innovation and Research Center, Switzerland. Electronic address:

We do not have a veridical representation of our body in our mind. For instance, tactile distances of equal measure along the medial-lateral axis of our limbs are generally perceived as larger than those running along the proximal-distal axis. This anisotropy in tactile distances reflects distortions in body-shape representation, such that the body parts are perceived as wider than they are.

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Dreaming conundrum.

J Sleep Res

October 2024

Department of Neuroimaging, Sleep and Brain Plasticity Centre, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.

Dreaming, a common yet mysterious cognitive phenomenon, is an involuntary process experienced by individuals during sleep. Although the fascination with dreams dates back to ancient times and gained therapeutic significance through psychoanalysis in the early twentieth century, its scientific investigation only gained momentum with the discovery of rapid eye movement (REM) sleep in the 1950s. This review synthesises current research on the neurobiological and psychological aspects of dreaming, including factors influencing dream recall and content, neurophysiological correlates, and experimental models, and discusses the implications for clinical practice.

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Article Synopsis
  • This study focuses on improving cochlear implant procedures by testing a new robotic tool designed to minimize trauma during the insertion of electrodes, which is crucial for preserving hearing in patients with some remaining inner ear function.
  • Using a validated model, the researchers conducted 60 insertions (30 manual and 30 robot-assisted) and found that the robotic method significantly reduced force variation and intracochlear pressure peaks compared to manual techniques.
  • The findings suggest that robotic assistance allows for more controlled and consistent insertion speeds, potentially enhancing hearing preservation while indicating that further research is needed to address later stages of the surgery.
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Objective: To explore Chat Generative Pretrained Transformer's (ChatGPT's) capability to create multiple-choice questions about otorhinolaryngology (ORL).

Study Design: Experimental question generation and exam simulation.

Setting: Tertiary academic center.

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Machine learning explainability techniques have been proposed as a means for psychologists to "explain" or interrogate a model in order to gain an understanding of a phenomenon of interest. Researchers concerned with imposing overly restrictive functional form (e.g.

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Characterizing bone density pattern and porosity in the human ossicular chain using synchrotron microtomography.

Sci Rep

August 2024

Department of Otorhinolaryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, Universityof Bern, Bern, Switzerland.

The auditory ossicles amplify and transmit sound from the environment to the inner ear. The distribution of bone mineral density is crucial for the proper functioning of sound transmission as the ossicles are suspended in an air-filled chamber. However, little is known about the distribution of bone mineral density along the human ossicular chain and within individual ossicles.

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Background: The acquisition of motor skills is a key element in many sports. A motor learning principle, which is frequently used to support skill acquisition is the application of different attentional foci. The effectiveness of different attentional foci on performance and the learning of motor skills has been investigated in various sports using randomised controlled trials.

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Follow-up strategies in pediatric cholesteatoma: a systematic review.

Eur Arch Otorhinolaryngol

January 2025

Task Force of the Young Otolaryngologists of the Italian Society of Otolaryngology-Head and Neck Surgery (GOS), Rome, Italy.

Purpose: The aim of this article was to systematically review the literature on the pediatric population surgically treated for cholesteatoma and describe the applied post-operative follow-up strategies.

Methods: A systematic review was conducted following the Primary Reporting Items for Systematic Review and Meta-analysis (PRISMA) statement recommendations. After running the selected search string in PubMed, Scopus and Google Scholar, studies in English, reporting on surgically treated pediatric cholesteatoma patients (age younger or equal to 18 year-old) were retrieved.

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Serial dependence: A matter of memory load.

Heliyon

July 2024

Laboratory of Psychophysics, Brain Mind Institute, École Polytechnique Fédérale de Lausanne (EPFL), Switzerland.

Unlabelled: In serial dependence, perceptual decisions are biased towards stimuli encountered in the recent past. Here, we investigate whether and how serial dependence is affected by the availability of visual working memory (VWM) resources. In two experiments, participants reproduced the orientation of a series of stimuli.

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Recent studies have shown that during the typical resting-state, echo planar imaging (EPI) time series obtained from the eye orbit area correlate with brain regions associated with oculomotor control and lower-level visual cortex. Here, we asked whether congenitally blind (CB) shows similar patterns, suggesting a hard-wired constraint on connectivity. We find that orbital EPI signals in CB do correlate with activity in the motor cortex, but less so with activity in the visual cortex.

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Purpose: To characterize the intra- and inter-operator reliability of a CT-based 3D preoperative planning software.

Materials And Methods: This study analyzed 30 CT scans of de-identified knees with osteoarthritis. For each scan, a case planner segmented the bones and pre-planned the TKA.

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