Spanning three decades: global research wave and future prospects of broader autism phenotype-a visual researches by CiteSpace and VOS viewer.

Objectives: To conduct a comprehensive review of the literature pertaining to the broader autism phenotype, the paper endeavors to delineate the key research directions and topics, document the current research trends, and furnish insightful analyses and novel perspectives to foster future advancements in the field, with the aid of CiteSpace and VOS viewer.

Methods: CiteSpace and VOS viewer are two kinds of software for visualizing citations that is intended to examine academic literature and identify possible sources of knowledge. The Web of Science Core Collection database was used to retrieve articles from 1994 to 2024 that discussed the autism phenotype in general.

Mechanism insights into customized 2D nanoconfined catalyst via peroxymonosulfate activation for efficient sulfamethoxazole degradation: Key roles of electronic structure and non-radical pathway.

The technology to solve the problem of the efficient pollutant removal in peroxymonosulfate (PMS) activation was the ultimate goal. There was an urgent need to achieving higher catalytic activity and oxidation efficiency. Herein, we present a MgAl-based layered double hydroxide assembled as a 2D confined catalyst (MgAl-Co-LDH) with Co metal in chelated form (Co-EDTA) for highly efficient PMS activation degrading sulfamethoxazole (SMX).

Exogenous acetate attenuates inflammatory responses through HIF-1α-dependent glycolysis regulation in macrophage.

Cytokine storm is a hallmark for acute systemic inflammatory disease like sepsis. Intrinsic microbiome-derived short-chain fatty acid (SCFAs) like acetate modulates immune cell function and metabolism has been well studied. However, it remains poorly investigated about the effects and the underlying mechanism of exogenous acetate in acute inflammation like sepsis.

Feasibility and preliminary efficacy of a systematic transaction model-guided dyadic coping nursing intervention for patients with breast cancer and their spousal caregivers: A pilot study.

Objective: This study aimed to assess the feasibility, acceptability, and preliminary efficacy of a Systematic Transaction Model (STM)-guided dyadic coping nursing intervention for patients with breast cancer and their spouses.

Methods: A single-arm, pre-test/post-test pilot study was conducted at a tertiary hospital in Wuxi, China, recruiting 28 breast cancer patient-caregiver pairs. Each dyad participated in six hybrid intervention sessions.

Novel photochromic system using methylene blue reduction with l-ascorbic acid.

A novel photochromic system was discovered, in which leucomethylene blue, reduced by l-ascorbic acid, was irradiated with 405 nm visible light, resulting in the solution undergoing a colorless-to-blue transition. The process was then repeated, with the solution returning to its colorless state when left undisturbed. This photochromic reaction is sensitive enough to be driven by a blue-violet LED lamp and enables figures to be drawn in solution with a laser pointer.

Outcomes of A2/A2B to B Deceased Donor Kidney Transplantation: A Retrospective Study.

Background A2/A2B to B kidney transplantation has the potential to increase transplant access for traditionally disadvantaged blood group B minority candidates. Despite prior reports of positive post-transplant safety and clinical success, A2/A2B to B kidney transplantation remains underutilized in the United States. This study aims to investigate the post-transplant outcomes of A2/A2B to B kidney transplants performed at our center.

Symptom clusters and network analysis in patients with gynecologic cancer undergoing chemotherapy: A cross-sectional study.

Objective: This study aimed to explore the complex relationships among symptoms and symptom clusters in patients with gynecologic cancer receiving chemotherapy using symptom network analysis, and to identify core symptoms and core symptom clusters.

Methods: A cross-sectional study was conducted at the Affiliated Hospital of Jiangnan University from December 2023 to June 2024, including 221 patients with gynecologic tumors. Participants completed demographic and clinical information questionnaires and the Chinese version of the MD Anderson Symptom Inventory (MDASI-C).

How Linguistic and Nonlinguistic Vocalizations Shape the Perception of Emotional Faces-An EEG Study.

Vocal emotions are crucial in guiding visual attention toward emotionally significant environmental events, such as recognizing emotional faces. This study employed continuous electroencephalography (EEG) recordings to examine the impact of linguistic and nonlinguistic vocalizations on facial emotion processing. Participants completed a facial emotion discrimination task while viewing fearful, happy, and neutral faces.

Diversity and Meta-Analysis of Microbial Differential Abundance in Nasal Metatranscriptomic Profiles of Asthma.

Asthma affects millions worldwide and involves complex genetic, immunological, and environmental factors. The nasal microbiome is increasingly recognized for its role in asthma development, but inconsistent results and small sample sizes have limited a clear understanding. We aimed to clarify the nasal microbiome's role in asthma using large datasets and meta-transcriptomic analysis.

Mechanisms Underlying the Therapeutic Effects of Yiqi Wenyang Huwei Decoction in Treating Asthma Based on GEO Datasets, Network Pharmacology, Experimental Validation, and Molecular Docking.

Purpose: The Yiqi Wenyang Huwei Decoction (YWHD) is an herbal formula frequently utilized to treat asthma. Despite its wide usage, the specific mechanism of action remains unknown. Through an in-depth investigation utilizing network pharmacology, molecular docking techniques, and experimental validation, this study aims to uncover the molecular mechanism and material basis of YWHD in the treatment of asthma.

Climate change and population aging: The role of older adults in climate change mitigation.

This paper explores the intersection of climate change, population aging, and community resilience, focusing on the potentially powerful roles of older adults in climate change mitigation efforts, particularly in developing countries. Through a brief review of relevant literature in the fields of environmental studies, gerontology, and community development, the paper examines the vulnerabilities of older adults to climate change impacts and their potential contributions to adaptation and mitigation strategies. By integrating findings from some existing literature, the paper contributes to ongoing conversations about the inclusivity of climate change actions and the empowerment of marginalized groups.

Novel design of potent anti-tumour activity of IL-2 prodrug by FAPα-mediated activation.

Interleukin-2 (IL-2) is a T cell growth factor that is essential for the proliferation of T cells and the generation of effector and memory cells. The antitumor activity of high-dose IL-2 therapy requires maintaining the affinity between IL-2 and IL2-Rα, which can also bring serious toxic side effects. To address this issue, we designed ZGP-Cysteamine-IL-2-K64C and (ZGP-Cysteamine)-IL-2-(K43C, K64C) based on the strategy of FAPα enzyme-activated prodrugs, and investigated their anti-tumour activity and side effects.

A new model based on preoperative AFP, albumin, and tumor burden score for predicting microvascular invasion in early-stage HCC.

Microscopic vascular invasion (MVI) has been demonstrated as a strong risk factor associated with tumor recurrence and poor overall survival among hepatocellular carcinoma (HCC) patients after resection, but the preoperative prediction of MVI is still challenging. We aimed to build and validate a novel model to predict MVI in the preoperative setting. We retrospectively collected 857 patients with Barcelona Clinic Liver Cancer (BCLC) stage 0 or A HCC who underwent primary resection at Kaohsiung Chang Gung Hospital between January 2001 and June 2016.

The effects of Tai Chi and Baduanjin on breast cancer patients: systematic review and meta-analysis of randomized controlled trials.

Background: Tai Chi and Baduanjin are nonpharmacological interventions that are widely applied among cancer patients.

Objective: This meta-analysis aimed to assess the effect of Tai Chi and Baduanjin on breast cancer patients by summarizing and pooling the results of previous studies.

Methods: The PubMed, Embase, Web of Science, Scopus and Cochrane Library and several databases were searched up to December 1, 2023, to identify high-quality RCTs.

The era of cybertaxonomy: X-ray microtomography reveals cryptic diversity and concealed cuticular sculpture in Voss, 1957 (Coleoptera, Curculionidae).

Weevils represent one of the most speciose and economically important animal clades, but remain poorly studied across much of the Oriental Region. Here, an integrative revision of the Oriental, flightless genus Voss, 1957 (Curculionidae: Molytinae) based on X-ray microtomography, multi-gene DNA barcoding (CO1, Cytb, 16S), and traditional morphological techniques (light microscopy, dissections) is presented. Twelve new species, namely, Lewis & Kojima, , Kojima & Lewis, , Lewis, , Lewis & Kojima, , Kojima, Lewis & Fujisawa, , Kojima & Lewis, , Lewis & Kojima, , Lewis & Kojima, , Kojima & Lewis, , Lewis & Kojima, , Lewis & Kojima, , and Lewis, Fujisawa & Kojima, are described from Japan, Taiwan, Vietnam, and Malaysia.

Establishment and drug resistance characterization of paired organoids using human primary colorectal cancer and matched tumor deposit specimens.

Tumor deposits (TDs) represent a specific form tumor metastasis observed in colorectal cancer (CRC). The lack of successfully established cell lines for TDs, as well as the molecular mechanisms by which TDs occur remain largely unknown. Here, we established paired CRC organoids, including a human primary cancer organoid and its TD organoid, from a 46-year-old male patient with CRC.

Degradation of Rhodamine B by Visible Light Driven MoO@TiO Core-Shell Photocatalyst.

In this study, a MoO@TiO composite core-shell material was developed to remove Rhodamine B (RhB) dye through synergistic adsorption and photocatalytic degradation. n-n heterostructures were formed by coupling n-type semiconductors to enhance the efficiency of photocarrier separation and photocatalytic performance. MoO, which possesses strong adsorption capacity, was primarily used as a dye adsorbent.

The packaging signal of Xanthomonas integrative filamentous phages.

Unlike Ff, the packaging signal (PS) and the mechanism of integrative filamentous phage assembly remains largely unknown. Here we revived two Inoviridae prophage sequences, ϕLf2 and ϕLf-UK, as infectious virions that lysogenize black rot pathogen Xanthomonas campestris pv. campestris.

Dynamic distribution of tetracycline and its degradation products in different organs of the geophagous earthworm Metaphire guillelmi.

Tetracycline (TC) residues in the environment are harmful to plants and animals; earthworms play an important role in detoxicating tetracycline in the soil. However, the response of different systems of the geophagous earthworm to TC and its degradation products is still not understood well. To understand this problem, Metaphire guillelmi were exposed to the soil contaminated by 100 mg kg tetracycline for 21 days.

Variation in the Local Grey Mullet Populations () on the Western Pacific Fringe.

: Understanding population genetic structures is crucial for planning and implementing conservation programmes to preserve species' adaptive and evolutionary potential and thus ensure their long-term persistence. The grey mullet () is a globally distributed coastal fish. Its populations in waters surrounding Taiwan on the western Pacific fringe are divided into at least two stocks (migratory and residential), but questions remain regarding their genetic divergence and gene flow.

The effects of microplastics exposure on quail's hypothalamus: Neurotransmission disturbance, cytokine imbalance and ROS/TGF-β/Akt/FoxO3a signaling disruption.

Microplastics (MPs) have become a major focus of environmental toxicology, raising concerns about their potential adverse effects on animal organs and body systems. As these tiny particles infiltrate ecosystems, they may pose risks to the health of organisms across diverse species. In this study, we attempted to examine the neurotoxic effects of MPs exposure on avian hypothalamus by using an animal model-Japanese quail (Coturnix japonica).

Fractional-Order Epidemic Model for Measles Infection.

In this study, a nonlinear dynamic SEVIQR measles epidemic model is constructed and analyzed using the novel Caputo fractional-order derivative operator. The model's existence and uniqueness are established. In addition, the model equilibria are determined, and the novel Jacobian determinant method recently constructed in the literature of epidemiological modeling of infectious diseases is applied to determine the threshold quantity, .

Impact of concurrent MASLD on early-stage HCC following curative resection in chronic hepatitis B.

In 2023, a new nomenclature, metabolic dysfunction-associated steatotic liver disease (MASLD), replaced the term non-alcoholic fatty liver disease (NAFLD). With the global rise in MASLD prevalence, concurrent MASLD and chronic hepatitis B (CHB)-related hepatocellular carcinoma (HCC) are becoming increasingly common. This study aimed to evaluate the clinical impact of concurrent MASLD on long-term survival outcomes in patients with CHB-related early-stage HCC following curative resection.