A budget impact model for biosimilar infliximab in Crohn's disease in Bulgaria, the Czech Republic, Hungary, Poland, Romania, and Slovakia.

Objectives: To estimate the budget impact of the introduction of biosimilar infliximab for the treatment of Crohn's disease (CD) in Bulgaria, the Czech Republic, Hungary, Poland, Romania and Slovakia.

Methods: A 3-year, prevalence-based budget impact analysis for biosimilar infliximab to treat CD was developed from third-party payers' perspective. The model included various scenarios depending on whether interchanging originator infliximab with biosimilar infliximab was allowed or not.

Treatment preferences of originator versus biosimilar drugs in Crohn's disease; discrete choice experiment among gastroenterologists.

Objective: To explore preferences of gastroenterologists for biosimilar drugs in Crohn's disease.

Material And Methods: Discrete choice experiment was carried out involving 51 Hungarian gastroenterologists in May 2014. The following attributes were used to describe hypothetical choice sets: 1) type of the treatment (biosimilar/originator), 2) severity of disease, 3) availability of continuous medicine supply, 4) frequency of the efficacy check-ups.

Moderate to severe psoriasis patients' subjective future expectations regarding health-related quality of life and longevity.

Background: Unrealistic expectations regarding treatments and clinical outcomes may lead to disappointment about therapy and sub-optimal compliance; nonetheless, these expectations have not been studied in psoriasis patients yet.

Objective: To evaluate psoriasis patients' subjective future expectations regarding health-related quality of life (HRQOL) and life expectancy, and to explore clinical features associated with under- or overestimating behaviour.

Methods: A cross-sectional questionnaire survey of consecutive adult patients with moderate to severe psoriasis was conducted.

Brachytherapy of vestibular schwannomas: report of three cases.

Objective: Gamma knife and multileaf collimator LINAC have recently gained notoriety in the treatment of vestibular schwannomas. Without the use of gamma knife or LINAC, we have successfully pursued the 125-iodine interstitial irradiation of three vestibular schwannomas.

Case Report: Up to March 2004, there was a 57 and 45 month follow-up period in two cases.

The importance of postoperative CT image fusion verification of stereotactic interstitial irradiation for brain tumors.

Purpose: The aim of our study was verification of the position of implanted catheters with (125)I seeds after the catheter implantation for the brachytherapy of brain tumors.

Methods And Materials: The fusion of the CT image used at planning and after the implantation of the catheters enabled us to verify the position of the catheters containing the isotopes. After this, the tumor volume covered by the prescribed dose (TV(PD)) and the normal tissue volume covered by the prescribed dose (NTV(PD)) were compared between the plan and the actual result.