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Mediators of a Mindfulness-Based Intervention for Younger Breast Cancer Survivors: Effects on Depressive Symptoms.

Psychosom Med

October 2024

From the Department of Psychology (Korecki, Bower), UCLA, Los Angeles; UCLA Jonsson Comprehensive Cancer Center (Ganz, Petersen, Crespi, Bower); Department of Health Policy and Management (Ganz), UCLA Fielding School of Public Health; Department of Medicine, Division of Hematology-Oncology (Ganz), David Geffen School of Medicine at UCLA, Los Angeles, California; Department of Medical Oncology (Partridge), Dana-Farber Cancer Institute; Department of Medicine (Partridge), Brigham and Women's Hospital; Harvard Medical School (Partridge), Boston, Massachusetts; The Johns Hopkins University School of Medicine and Sidney Kimmel Comprehensive Cancer Center (Wolff), Baltimore, Maryland; Department of Biostatistics (Crespi), UCLA Fielding School of Public Health; Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine (Bower), UCLA, Los Angeles; and Cousins Center for Psychoneuroimmunology, Semel Institute for Neuroscience and Human Behavior (Bower), Los Angeles, California.

Article Synopsis
  • - The study aimed to understand how mindfulness-based interventions (MBIs) and psychoeducation programs impact depressive symptoms in younger women with breast cancer, focusing on specific psychological factors that may mediate these effects.
  • - It involved 243 women diagnosed with early-stage breast cancer, who were assigned to different interventions (Mindful Awareness Practices, Survivorship Education, or a wait-list control), with assessments at various points to measure depressive symptoms and related psychological factors.
  • - Results showed that both interventions significantly reduced depressive symptoms, with mindfulness practices particularly linked to improvements in rumination, self-kindness, and feelings of meaning, which may help in enhancing the effectiveness of future interventions.
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