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Zinc deficiency decreases plasma erythropoietin concentration in rats.
Biol Trace Elem Res
December 2005
Department of Human Nutrition, Seitoku University Graduate School Matsudo, Chiba 271-8555, Japan.
In 1985, Paterson and Bettger found hypoplastic hematopoiesis in severely zinc-deficient rats. Therefore, we investigated plasma erythropoietin concentration in zinc-deficient rats. Forty 4-wk-old male Sprague- Dawley rats were assigned into 4 dietary treatment groups of 10 for the 4-wk study: zinc-deficient group (4.
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