1,147 results match your criteria: "Seirei-Hamamatsu General Hospital[Affiliation]"

The full-field stimulus test (FST) is a psychophysical technique designed for the measurement of visual function in low vision. The method involves the use of a ganzfeld stimulator, as used in routine full-field electroretinography, to deliver full-field flashes of light. This guideline was developed jointly by the International Society for Clinical Electrophysiology of Vision (ISCEV) and Imaging and Perimetry Society (IPS) in order to provide technical information, promote consistency of testing and reporting, and encourage convergence of methods for FST.

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  • The study aimed to examine the occurrence and risk factors for inguinal hernia (IH) following robot-assisted radical prostatectomy (RARP) using data from 3,195 Japanese patients from 2012 to 2021.
  • Various surgical techniques were evaluated for IH prevention, but none showed a significant impact on reducing IH development, which affected 243 patients during a median follow-up of 24 months.
  • Key risk factors for developing IH included older age, low BMI, and low hospital volume; the findings suggest the need for further research to enhance surgical techniques for IH prevention.
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  • Cell therapy using MultiStem, a multipotent progenitor cell product from bone marrow, is being evaluated for its potential to treat ischemic stroke, which involves a lack of blood flow to the brain.
  • The TREASURE trial, a double-blind, placebo-controlled study conducted at 44 centers in Japan, aimed to determine the safety and efficacy of MultiStem when given to patients within 18-36 hours of stroke onset.
  • Key outcomes were measured through various scales at 90 and 365 days post-treatment, assessing safety and overall recovery, with the study involving 206 patients (104 receiving MultiStem and 102 receiving placebo).
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  • Istradefylline (IST) is investigated as an adjunctive treatment for Parkinson's disease (PD) to see if it can reduce the need for higher doses of levodopa, which is commonly linked to motor complications.
  • In a study with 114 PD patients experiencing wearing-off symptoms, those receiving IST required significantly less additional levodopa over 37 weeks compared to those who did not receive IST.
  • Patients treated with IST also showed improvements in motor functions measured by rating scales and wearable devices, suggesting that IST may enhance symptom management without increasing levodopa dosage significantly.
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Introduction: Streptococcus mutans (SM) with the collagen-binding protein Cnm is a unique member of the oral resident flora because it causes hemorrhagic vascular disorders. In the multicenter study, we examined the relationship between Cnm-positive SM (CP-SM) and intracranial aneurysm (IA) rupture, which remains unknown.

Methods: Between May 2013 and June 2018, we collected whole saliva samples from 431 patients with ruptured IAs (RIAs) and 470 patients with unruptured IAs (UIAs).

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  • The study explored the link between lymphovascular invasion (LVI) and oncological outcomes in prostate cancer patients who underwent robotic-assisted radical prostatectomy (RARP).
  • Out of 3195 patients, 2608 met the criteria, with 11.9% experiencing biochemical recurrence (BCR), showing that LVI adversely affects BCR-free survival and metastasis-free survival in certain patient groups.
  • The findings indicate that LVI is a significant independent prognostic factor for recurrence and metastasis, especially in patients with locally advanced disease, highlighting the need for close monitoring in these cases.
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Changes in temporal muscle dimensions and their clinical impact in out-of-hospital cardiac arrest survivors.

Resusc Plus

March 2024

Department of Emergency, Critical Care, and Disaster Medicine, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Okayama Kita-ku, Okayama 700-8558, Japan.

Objective: This study investigates temporal muscle atrophy in out-of-hospital cardiac arrest patients post-resuscitation, seeking associations with neurological outcomes and factors associated with atrophy.

Methods: Using data from six Japanese intensive care units, adult patients' post-resuscitation who underwent head computed tomography scans on admission and two to five days post-admission were assessed. Temporal muscle area, thickness, and density were quantified from a single cross-sectional image.

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  • Serum IFNλ3 levels were significantly higher in patients with polymyositis/dermatomyositis (PM/DM)-associated interstitial lung disease (ILD) compared to healthy controls, particularly in those with anti-MDA5 antibodies.
  • High serum IFNλ3 levels (>120 pg/mL) were linked to lower survival rates among anti-MDA5 antibody-positive DM-ILD patients, alongside factors like older age and low Pao.
  • This study suggests that serum IFNλ3 could serve as an important biomarker to identify high-risk patients with anti-MDA5 antibody-positive DM-ILD for poorer outcomes.
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: We aimed to examine the relationship between the inflammation-related parameters, such as the neutrophil-to-lymphocyte ratio (NLR), and the pathological findings and biochemical recurrence (BCR) in patients with prostate cancer (PCa) undergoing robot-assisted radical prostatectomy (RARP). : A retrospective multicenter cohort study of patients with PCa who underwent RARP at 10 institutes in Japan was conducted. This study enrolled 3195 patients.

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A man in his 40s with ST-segment elevation myocardial infarction complicating cardiogenic shock was transferred to our hospital. Emergent percutaneous coronary intervention for the left anterior descending and left circumflex arteries supported with Impella CP was performed. However, his cardiac function was severely impaired, and anuria developed, necessitating continuous renal replacement therapy (CRRT).

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Kikuchi-Fujimoto disease (KFD) is a self-limiting disease, characterised by fever and cervical lymphadenopathy. Lymphadenopathy without cervical lymph node involvement is rare and may mimic lymphoma. Although KFD can be associated with extranodal involvement, muscle involvement has not been reported.

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Predictive factors for postoperative visual function in eyes with epiretinal membrane.

Sci Rep

December 2023

Department of Ophthalmology and Micro-Technology, Yokohama City University, 4-57 Urafune, Minami-ku, Yokohama, Kanagawa, 232-0024, Japan.

Our current study aimed to investigate the association of preoperative OCT parameters with visual function after vitrectomy surgery in eyes with epiretinal membrane (ERM). This study enrolled 33 eyes with ERM that underwent vitrectomy surgery. In addition to visual acuity (VA), metamorphopsia was measured pre- and postoperatively for each eye.

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The present study aimed to compare retinal sensitivity (RS) at each stage and to evaluate the relationship between RS and fundus autofluorescence (FAF) pattern in adult-onset foveomacular vitelliform dystrophy (AOFVD). We retrospectively reviewed 17 eyes of 13 patients with AOFVD. In addition to best-corrected visual acuity (VA), RS within the affected lesion and optical coherence tomography (OCT) measurements were carried out in each participant.

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  • Dexamethasone is commonly used for preventing nausea and vomiting in chemotherapy patients but has notable side effects, leading to the exploration of a steroid-free antiemetic regimen.
  • The study evaluated the effectiveness and safety of a combination of palonosetron, aprepitant, and olanzapine in patients receiving cisplatin, finding a total control rate of 31.3% and complete response rates of 61.4%, 84.3%, and 65.1% in different phases.
  • While the primary endpoint wasn't met, the complete response rates were comparable to traditional regimens, suggesting this dexamethasone-free option could be beneficial for patients unable to use corticosteroids.
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  • The study investigates the link between pharmacokinetic parameters of direct oral anticoagulants (DOACs) and the risk of post-endoscopic submucosal dissection (ESD) bleeding, noting that GI bleeding is a significant concern.
  • It found a 12.8% incidence of post-ESD bleeding in patients on DOACs, with factors such as age and FXa activity correlating significantly with bleeding risk.
  • The research suggests that measuring drug levels and anticoagulant effectiveness could help identify patients at higher risk for bleeding after ESD procedures.
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Purpose: In a previous cross-sectional study, we reported that the sexes can be distinguished using known factors obtained from color fundus photography (CFP). However, it is not clear how sex differences in fundus parameters appear across the human lifespan. Therefore, we conducted a cohort study to investigate sex determination based on fundus parameters in elementary school students.

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Rotating suture technique combined with lid margin split and lower eyelid retractor disinsertion for epiblepharon.

J Plast Reconstr Aesthet Surg

January 2024

Department of Plastic and Reconstructive Surgery, Yokohama City University Hospital, 3-9 Fukuura, Kanazawa-ku, Yokohama-shi, Kanagawa 236-0004, Japan.

Epiblepharon is an eyelid disease affecting 46-52.5% of Asian children. The Hotz procedure was commonly used for the treatment.

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Background: The impact of unilateral and bilateral nerve-sparing robot-assisted laparoscopic radical prostatectomy (NS-RARP) procedures on continence and the time to continence recovery have not been established.

Material And Methods: We retrospectively reviewed a total of 2801 patients who underwent RARP in 9 institutions. Procedures were classified as NS or non-NS; NS procedures were further classified as unilateral or bilateral.

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Objectives: This study aimed to examine the association between ABCDEF bundles and long-term postintensive care syndrome (PICS)-related outcomes.

Design: Secondary analysis of the J-PICS study.

Setting: This study was simultaneously conducted in 14 centers and 16 ICUs in Japan between April 1, 2019, and September 30, 2019.

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Atrial fibrillation (AF) can occur predominantly associated with right atrial (RA) lesions in congenital heart disease, particularly when the RA cavity is dilated. RA electrical potentials occasionally appear organized during AF. We clearly mapped such areas circumscribed by an intra-atrial re-entrant circuit during an isoproterenol infusion, in a patient with a repaired tetralogy of Fallot, using an ultrahigh-density mapping system and its beat acceptance criteria function.

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Purpose: To develop a method to measure the macular pigment optical density (MPOD) using scanning laser ophthalmoscopic images in young adults and children.

Study Design: Cross-sectional study.

Methods: Blue light reflectance fundus images of 32 healthy subjects were used.

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Minimally invasive glaucoma surgery has expanded the surgical treatment options in glaucoma, particularly when combined with cataract surgery. It is clinically relevant to understand the associated postoperative changes in biomechanical properties because they are influential on the measurement of intraocular pressure (IOP) and play an important role in the pathogenesis of open-angle glaucoma (OAG). This retrospective case-control study included OAG patients who underwent cataract surgery combined with microhook ab interno trabeculotomy (µLOT group: 53 eyes of 36 patients) or iStent implantation (iStent group: 59 eyes of 37 patients) and 62 eyes of 42 solo cataract patients without glaucoma as a control group.

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Introduction: Adrenal lymphangioma is a rare benign tumor of lymphatic origin, usually incidentally detected from various imaging studies taken for an unrelated purpose. We present a case of a right adrenal lymphangioma treated successfully with surgical intervention.

Case Presentation: A 36-year-old previously healthy woman was referred to our urology department for a right adrenal mass, discovered during a routine health checkup.

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Purpose: In binocular vision, there is a dominant eye and a nondominant eye, a phenomenon termed ocular dominance. This study determined the differences and associations of the ocular blood flow parameters between dominant and nondominant eyes in healthy Japanese subjects.

Methods: This cross-sectional study included 128 eyes of 64 subjects (13 male and 51 female) aged ≥ 20 years.

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Purpose: To clarify the abilities of circumpapillary retinal nerve fiber layer thickness (cpRNFLT) obtained by optical coherence tomography (OCT) and circumpapillary vessel density (cpVD) measured by OCT-angiography to distinguish different stages in primary open-angle glaucoma determined by 24-2 or 30-2 static visual field (VF) testing.

Methods: This retrospective study includes 25 healthy normal eyes of 25 subjects and 87 primary open-angle glaucoma eyes of 87 patients. Areas under the receiver operating characteristic curves (AUROC) were evaluated for determining glaucoma stages using cpRNFLT and cpVD.

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