A study of 50 children with Down syndrome revealed that 14% tested positive for antithyroid antibodies, indicating a potential autoimmune response.
Six individuals had antimicrosomal antibodies and three had both antimicrosomal and antithyroglobulin antibodies, while none tested positive for antithyroglobulin alone.
Three children in the Down syndrome group were diagnosed with hypothyroidism, highlighting the need for regular screening for thyroid issues in this population.