1 results match your criteria: "Section of Pediatric Gastroenterology Baylor College of Medicine Houston Texas USA.[Affiliation]"
Article Synopsis
- The experiment aimed to link variations in gut microbiome composition to the susceptibility of inflammatory bowel disease (IBD) and explore a potential preventive probiotic for newborns.
- C57BL/BJ mice were subjected to acute colitis using dextran sodium sulfate (DSS) to serve as a model for IBD, while specific protective bacteria were tested through maternal probiotic supplementation during lactation.
- Results showed that maternal supplementation with certain bacterial strains enhanced microbiome diversity and provided significant protection against colitis in young adult female mice, paving the way for future probiotic development targeting IBD in humans.