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[Role of Ang-2 in the rats model of LPS-induced acute lung injury].

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi

November 2009

Yongchuan Hospital Affiliated to Chongqing University of Medical Sciences, Second People's Hospital Chongqing, Chongqing 402160, China.

Aim: To investigate the potential role of angiopoietin-2 in the rats model of lipopolysaccharide (LPS)-induced acute lung injury (ALI).

Methods: Wistar rats were randomly divided into four groups(n=10): control group; in LPS groups, rats were divided into three subgroups, treated with different dosage of LPS (2 mg/kg, 4 mg/kg and 8 mg/kg). ALI model was established by intravenous injection with LPS, while control group was with NS.

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