Isolation ssDNA aptamers specific for both live and viable but nonculturable state using whole bacteria-SEILEX technology.

is a ubiquitous marine bacterium that may cause rapid and deadly infection, threatening lives of people living around natural bodies of water, especially in coastal regions. However, traditional culture-based methods are time-consuming and unable to detect Viable But Non-Culturable (VBNC) cells. In this work, we isolated a batch of detection aptamers specifically binding to in all culture status.