The upregulation of peripheral blood polyamine metabolites spermidine and spermine in children with hand, foot, mouth disease is related to enterovirus 71 capsid protein VP1, but not VP4.

Background: Hand, foot, and mouth disease (HFMD) is a common viral childhood illness caused most commonly by enterovirus 71 (EV71) and coxsackievirus A16. The pathogenesis of EV71 has been extensively studied, and the regulation of the host immune response is suspected to aggravate the serious complications induced by EV71. Our previous research showed that EV71 infection significantly increased the release of circulating interleukin (IL)-6, IL-10, IL-13, and IL-27.

Recognition of Ultrasound Artifact Mimicking Pulmonary Artery Dissection in Patients with Heart Disease.

Purpose: Imaging artifacts are frequently encountered when performing clinical echocardiography. Based on our review of the literature, two-dimensional linear artifacts are mainly reported in the ascending aorta in patients with suspected aortic dissections. However, pulmonary artery artifacts that mimic pulmonary artery dissection have not been discussed.

[The surgical treatment discussion in intractable Meniere's disease: lateral and posterior semicircular canal plugging with endolymphatic sac decompression].

To introduce and discuss a surgical technique, i.e. lateral and posterior semicircular canal plugging with endolymphatic sac decompression, to treat intractable Meniere's disease.

S100A10 as a novel biomarker in colorectal cancer.

Recent data support the role of S100A10 in tumorigenesis. In this study, we evaluated the value of S100A10 positivity as a possible biomarker in colorectal cancer. We evaluated S100A10 positivity by immunohistochemistry in a large population of colorectal cancer patients (n = 882).