Different Antibody Response against the Coxsackievirus A16 VP1 Capsid Protein: Specific or Non-Specific.

Coxsackievirus A16 (CA16) is one of the major causative agents of hand, foot, and mouth disease worldwide. The non-neutralizing antibody response that targets CA16 VP1 remains poorly elucidated. In the present study, antibody responses against CA16 VP1 in Shanghai blood donors and Shanxi individuals were analyzed by ELISA and inhibitory ELISA using five CA16 VP1 antigens: VP11-297, VP141-297, VP11-60, VP145-58 and VP161-297.

[Improvement on bilateral cleft lip repair].

The deformity of the bilateral cleft lip is complicated. The routine procedure often results in secondary deformities, such as over-tight lip, and over-thin vermilion. The paper introduces a modified straight-line procedure that has been used in 16 patients with satisfactory results.

[Laparoscopic diagnosis of tubal infertility and fallopian tube lesions].

Objective: To analyse the diagnostic value of laparoscopy in patients with tubal infertility.

Methods: The morphological appearance of fallopian tubes and surrounding tissues of 1120 cases with proven tubal infertility were observed under laparoscopy. Hydrotubation was performed at the same time in each case.

The combination of melphalan, cyclophosphamide and cytosine arabinoside as a conditioning regimen for autologous bone marrow transplantation for acute leukemia.

Objective: To explore more effective and less toxic conditioning regimen without total body irradiation for autologous bone marrow transplantation (ABMT) for acute leukemia (AL).

Material And Methods: Twenty patients with AL were treated with ABMT, including 13 cases of acute myelocytic leukemia (AML) and 7 cases of acute lymphocytic leukemia (ALL). A median of 1.

[Megaloblastic changes in cervical epithelium associated with oral contraceptives and changes after treatment with folic acid].

Objective: To study the influence of oral contraceptives on cervical epithelium, serum and red blood cell folate levels of users and to observe the changes after treatment with folic acid.

Methods: Morphology of cervical epithelium, serum folate and red blood cell folate levels were studied in 101 women who had used oral contraceptives for over 6 months and 33 intrauterine devices users served as controls, 29 women using oral contraceptives with cervical megaloblastic changes were treated with folic acid (5mg daily) for 3-4 weeks and followed up for observation on morphological changes of cervical epithelium.

Results: The mean nuclear diameter of cervical epithelial cells was larger in the oral contraceptive group than that in the control group (P < 0.

[Erythropoietin treatment of anemia associated with multiple myeloma (MM) and myelodysplastic syndrome (MDS)].

Anemia is a common complication of patients with multiple myeloma (MM) and myelodysplastic syndrome (MDS). Most of these patients often require blood transfusion. 12 patients, including 7 cases of MM and 5 cases of MDS, were treated with rhEPO 10,000 micrograms three times a week for 15 weeks.

[221 cases of laparoscopic laser therapy].

Laparoscopic laser therapy, using a Nd:YAG laser and an Olympus laparoscope, was performed in 221 cases. 0.5% dicaine spray was used intraperitoneally.

[Ultrastructural study of the megakaryocytes in megaloblastic anemia].

The ultrastructure of the megakaryocytes in the bone marrow from 14 cases of megaloblastic anemia was studied. The commonest change observed was that the development of the nucleus lagged behind that of the cytoplasm. There were some evidences supporting the theory of ineffective thrombocytopoiesis.