2 results match your criteria: "Second Affiliated Hospital of Hunan University of Chinese medicine Changsha 410005[Affiliation]"
[Effect of Naotaifang on microglial polarization and glial scar following cerebral ischemia reperfusion injury].
Zhongguo Zhong Yao Za Zhi
February 2024
Key Laboratory of Hunan Province for Integrated Traditional Chinese and Western Medicine on Prevention and Treatment of Cardio-Cerebral Diseases,College of Integrated Traditional and Western Medicine, Hunan University of Chinese Medicine Changsha 410208,China.
Article Synopsis
- This study examines how Naotaifang (NTF) influences proteins linked to microglial polarization and glial scar formation in rats with cerebral ischemia reperfusion injury (CIRI).
- The research involved creating a rat CIRI model and dividing 48 rats into different treatment groups to evaluate the effects of NTF over 7 and 14 days.
- Results indicated that NTF treatment improved cognitive function and reduced brain damage and anxiety levels compared to the untreated model groups, showing potential benefits for recovery from brain injuries.
[Effects of astragaloside Ⅳ on inflammatory response and percentage of peripheral blood Th17 cells in mice with ulcerative colitis].
Zhongguo Zhong Yao Za Zhi
January 2022
Anorectal Department, Second Affiliated Hospital of Hunan University of Chinese medicine Changsha 410005, China.
This study aimed to investigate the anti-inflammatory effect of astragaloside Ⅳ in mice with ulcerative colitis(UC) and its effect on the percentage of peripheral blood T helper(Th17) cells. Following the establishment of UC mouse model with 2% sodium dextran sulfate(DSS), mice in the positive control group and low-and high-dose astragaloside Ⅳ groups were treated with corresponding drugs by gavage. Disease activity index(DAI) was calculated, and serum interleukin-17(IL-17), tumor necrosis factor-α(TNF-α), and transforming growth factor-β(TGF-β) levels were assayed by ELISA.
View Article and Find Full Text PDF