Role of gut microbiota in the modulation of the health effects of advanced glycation end‑products (Review).

The aim of the present review was to summarize the potential interactive effects between the gut microbiota and advanced glycation end‑product (AGE) accumulation and toxicity in the host, and to reveal potential the mediatory effects of the gut microbiota on AGE‑related health effects. The existing data demonstrate that dietary AGEs can have a significant impact on the richness and diversity of the gut microbiota, although the particular effect is dependent on the type of species, as well as the exposure dose. In addition, the gut microbiota may metabolize dietary AGEs.