[Risk factors for pancreatitis and pancreatic cancer].

Aim: To identify and compare the frequency of alcohol consumption, tobacco smoking, levels of main macronutrients, vitamins and mineral elements consumption in patients with acute (AP) and chronic pancreatitis (CP) and pancreatic cancer (PC).

Materials And Methods: At the observational clinical cross-sectional uncontrolled case-study 65 patients with AP or CP (group 1) and 45 patients with PC (group 2) were examined. A survey of patients was carried out: questionnaire on tobacco smoking, a frequency questionnaire on alcohol consumption, a questionnaire for assessing the frequency of food consumption.

Levels of depression and life exhaustion in the open population of the middle urbanized Siberian city: gender differences.

Aim: The aim of the study was to determine the levels of depression and life exhaustion in men and women of the open urban population in the age range.

Materials And Methods: A single-stage epidemiological study was conducted among people of both sexes aged 25-64 in Tyumen. A representative sample was formed from the electoral lists of citizens by the method of "random numbers" - 2000 men and women with a response among men 85.

[Intronic polymorphisms of аntionkogene TP53 in patients with indolent variants of Non-Hodgkin's lymphomas].

The frequency of distribution of alleles and genotypes of single nucleotide substitution G13494A in intron 6 and duplications dup16bp in intron 3 of the gene TP53 in 56 patients with indolent non-Hodgkin's lymphoma and variants in the controls was studied. The increase of the frequency of G-allele and G/G genotype of intron 6 of the gene TP53 in lymphoma patients compared with controls (91 and 84 % vs. 79 (p<0,01) and 63 % (p<0,01), respectively) was determined.

[Beneficial effects of Hartil on cardiovascular remodeling process in elderly and old patients with isolated systolic arterial hypertension].

The aim of present study was to assess antihypertensive efficacy of ramipril 5-10 mg (Hartil "EGIS", Hungary) and its influence on hemodynamical changes and vessel endothelial function in old and elderly patients with isolated systolic hypertension. 32 patients were studied. The duration of the therapy was 6 months.