1 results match your criteria: "Science and Technology Park of Islamic Azad University[Affiliation]"
An Optimized Process for the Preparation of Aqueous Ferric Carboxymaltose: Synthesis and Structural Characterization.
Pharm Nanotechnol
October 2021
Research and Development unit, Nafas Zist Pharmed Pharmaceutical Company, Science and Technology Park of Islamic Azad University, Tehran, Iran.
Background: Ferric carboxymaltose (FCM) formulation consists of iron-carbohydrate nanoparticles where iron-oxyhydroxide as a core is covered by a carbohydrate shell. The present work provides an improved synthesis process of FCM as an intravenous iron, active pharmaceutical ingredient.
Methods: Water-soluble FCM complex was prepared from the reaction of ferric hydroxide precipitation with an aqueous solution of oxidized maltodextrin (MD) at optimum temperature and pH conditions.