Anxiety mediated the relationship between bullying victimization and internet addiction in adolescents, and family support moderated the relationship.

Objective: This study aims to discuss anxiety in mediating role between bullying victimization and adolescent internet addiction, and the moderating role of family support between bullying victimization and adolescent anxiety.

Methods: A cross-sectional study was conducted in 5 provinces of China by convenience sampling from February to March 2024. A total of 1395 participants (599 boys and 796 girls) with an average age of 15.

The effects of dance interventions on reducing the risk of falls in older adults: a network meta-analysis.

Objective: The efficacy of dance in reducing fall risks among older adults highlights its potential for geriatric health, but the optimal dance style remains uncertain. The present study endeavors to systematically analyze the effects of various dance forms on reducing the risk of falls among older adult, with the aim of providing evidence-based insights into the most efficacious dance styles for this population.

Design: The network meta-analysis of the existing literature was conducted to synthesize the available evidence regarding the effectiveness of various dance interventions in reducing the risk of falls among older adults.

Evaluation of Factors Associated With Short-term Failure After Primary Isolated PCL Reconstruction: A Study of Patients From the Swedish and Norwegian Knee Ligament Registries.

Background: The rate of subjective failure after isolated primary posterior cruciate ligament reconstruction (PCL-R) is relatively high, requiring an improved understanding of factors associated with inferior outcomes.

Purpose: To determine the association between patient and injury-related factors and total (surgical and clinical) failure at 2 years after PCL-R based on data from the Swedish National Knee Ligament Registry (SNKLR) and the Norwegian Knee Ligament Registry (NKLR).

Study Design: Cohort study; Level of evidence, 3.

Differential Expression of GABA Receptor-Related Genes in Alzheimer's Disease and the Positive Regulatory Role of Aerobic Exercise-From Genetic Screening to D-gal-induced AD-like Pathology Model.

Alzheimer's disease (AD) is the most common neurodegenerative disorder. The neuropathology of AD appears in the hippocampus. The purpose of this work was to reveal key differentially expressed genes (DEGs) in the hippocampus of AD patients and healthy individuals.

Game-related statistics for distinguishing winning and losing teams in Olympic basketball: The impact of game pace.

The pace of play, a critical tactical element in basketball, significantly influences offensive and defensive strategies. This study aimed to identify statistical indicators that differentiate winners from losers across varying game paces using a sample of 90 Olympic men's basketball games from 2016, 2021, and 2024. Games were categorized as fast-paced or slow-paced via clustering algorithms.

Multimorbidity and Depression Increase Prevalence of Frailty of Community-dwelling Indonesian Older Adults: Indonesia Care Networks Study.

Background: Older adults with frailty have an increased risk of multiple negative health outcomes, such as disability, falls, and morbidity when exposed to physical stressors. The present study investigated the prevalence of frailty and associated risk factors among community-dwelling Indonesian older adults in several districts in Jakarta, Indonesia.

Methods: This cross-sectional study was done in several urban villages in Jakarta, Indonesia.

The mediation effect of peer relation and positive emotion between campus sports atmosphere and teenagers' subjective well-being.

Background: The healthy growth of young people affects the future of every country and nation. Their physical and psychological health problems have long been the focal point of every country. The purpose of this study is to investigate the influence of campus sports atmosphere on the teenagers' subjective well-being.

Patient-Reported Outcomes of Bicruciate Multiligament Versus Single Cruciate Multiligament Knee Injuries.

Background: Multiligament knee injuries (MLKIs) are heterogeneous, and bicruciate knee ligament injuries are considered a serious form of this injury. The current literature tends not to distinguish between single and bicruciate MLKI when reporting outcomes.

Purpose: To investigate patient-reported outcomes after surgical treatment of MLKI comparing single cruciate MLKI with bicruciate MLKI.

Myxobacteria from soil can substantially reduce the bacterial load in a wound infection model.

Aims: Myxobacteria are non-pathogenic, saprophytic, soil-dwelling predatory bacteria known for their antimicrobial potential. Many pathogenic bacteria form biofilms to protect themselves from antimicrobial agents and the immune system. This study has investigated the predatory activities of myxobacteria against pathogenic bacteria in biofilms.

The Risk of Disordered Eating in Fitness Club Members-A Cross-Sectional Study.

Fitness clubs may be environments where abnormal eating behaviors and excessive exercise are socially accepted, potentially putting individuals at risk for disordered eating (DE). This study examined the DE risk prevalence among gym members, comparing body appreciation, exercise motivation, frequency, BMI, and age across DE risk levels, and assessed the associated factors. A sample of 232 gym members (age: 39.

Exploring the pharmacological mechanisms for alleviating OSA: Adenosine A2A receptor downregulation of the PI3K/Akt/HIF‑1 pathway (Review).

Obstructive sleep apnea (OSA) is the most common type of sleep apnea, which leads to episodes of intermittent hypoxia due to obstruction of the upper airway. A key feature of OSA is the upregulation and stabilization of hypoxia-inducible factor 1 (HIF-1), a crucial metabolic regulator that facilitates rapid adaptation to changes in oxygen availability. Adenosine A2A receptor (A2AR), a major adenosine receptor, regulates HIF-1 under hypoxic conditions, exerting anti-inflammatory properties and affecting lipid metabolism.

Different types of pesticide exposure and lung cancer incidence in the Agricultural Health Study cohort: A systematic review and meta-analysis.

Lung cancer is the dominant cause of worldwide cancer mortality. The relationship between pesticide exposure and lung cancer risk has shown mixed results epidemiologically. We hypothesized this discrepancy could arise from the varying effects of different pesticides and conducted this meta-analysis by using three pesticide classification schemes to examine the implications of diverse pesticide exposure types on lung cancer risk.

Near-infrared light induces neurogenesis and modulates anxiety-like behavior.

Background: The hippocampus is associated with mood disorders, and the activation of quiescent neurogenesis has been linked to anxiolytic effects. Near-infrared (NIR) light has shown potential to improve learning and memory in human and animal models. Despite the vast amount of information regarding the effect of visible light, there is a significant gap in our understanding regarding the response of neural stem cells (NSCs) to NIR stimulation, particularly in anxiety-like behavior.

Effects of exercise on sleep quality in women - A systematic review and meta-analysis.

Objectives: Insomnia affects at least one-third of the global population and is more common in women. Exercise has been reported to improve sleep quality and subsequent use of hypnotics. Therefore, we performed a meta-analysis to assess the effect of exercise on sleep quality in adult women.

An experimental and computational approach to evaluate the antidiabetic activity of Commiphora wightii gum extract.

Background: Plant formulations with antidiabetic and antioxidant properties have recently gained popularity due to their lower cost and lesser side effects. Guggul gum is one such formulation that is extensively being used to cure various ailments.

Objective: The present study was designed to explore the antioxidant and antidiabetic properties of the aqua-ethanolic Guggul gum extract (GE) from Commiphora wightii using in silico studies and in vitro assays.

Hydrogen gas inhalation prior to high-intensity training reduces attenuation of nitric oxide bioavailability in male rugby players.

Background: Inhalation of hydrogen gas (H) as an antioxidant supplement may alleviate exercise-induced oxidative damage and protect post-exercise hydrogen peroxide signaling, which may help mediate beneficial exercise adaptation. The aims of this study were to determine the effects of H inhalation on plasma nitric oxide (NO) level and its synthesis precursor in professional athletes.

Methods: A randomized, placebo-controlled, double-blind, crossover trial was conducted with professional male rugby players for 3 weeks.

Platelet-rich plasma combined with isometric quadriceps contraction regulates autophagy in chondrocytes via the PI3K/AKT/mTOR pathway to promote cartilage repair in knee osteoarthritis.

Background: This study investigated the molecular mechanism by which the combination of platelet-rich plasma (PRP) and isometric contraction of the quadriceps (ICQ) intervention regulates autophagy in chondrocytes to prevent and treat knee osteoarthritis (KOA).

Methods: Thirty Sprague-Dawley rats were divided into a control group (CG, n = 6) and a model group (n = 24). After one week, the model group was randomly divided into a joint intervention group (JIG), a rapamycin group (RAG), an MHY1485 group (MYG), and a model blank group (MBG), with JIG, RAG, and MYG receiving the same combined intervention.

The relationship between physical exercise and depressive symptoms in college students: the mediating role of rumination.

Objective: This study aims to explore the correlation between physical exercise, rumination, and depressive symptoms in college students, as well as to investigate the potential pathways through which physical exercise may impact depressive symptoms. This exploration offers valuable insights for the development of clinical exercise interventions.

Methods: A cross-sectional study design was employed, with 2,902 participants recruited via convenience sampling.

Postexercise downregulation of in regulating non-small cell lung cancer progression via the PTEN/AKT signaling pathway.

Background: Research interest into regulation of gene expression by physical activity and its effect on cancer prognosis has intensified. This study investigated the role of an exercise-related gene, , in the progression of non-small cell lung cancer (NSCLC) and its potential as therapy target.

Methods: Using the GSE41914 dataset, which includes data related to exercise, and the Cancer Genome Atlas (TCGA)-NSCLC dataset, we identified differentially expressed genes (DEGs) and selected as a hub gene for further analysis.

Optimal intensity and dose of exercise to improve university students' mental health: a systematic review and network meta-analysis of 48 randomized controlled trials.

Background: A systematic evaluation and network meta-analysis (NMA) using randomized controlled trials (RCTs) was conducted to investigate the effects of different exercise intensities and dosages on the mental health of college students.

Methods: A systematic search of eight electronic databases of RCTs involving mental health exercise interventions for college students was conducted, which included data from the inception of the databases through July 2024. Two independent reviewers assessed the quality of the literature.

Associations of sarcopenia and malnutrition with 30-day in-hospital morbidity and mortality after cardiac surgery.

Objectives: Sarcopenia and malnutrition often occur simultaneously in adults with cardiovascular diseases. Our objective was to determine the associations of preoperative sarcopenia and malnutrition with major adverse cardiac and cerebral events (MACCE) after cardiac surgery.

Methods: We retrospectively analysed 154 consecutive patients who underwent elective cardiac surgery between January 2015 and June 2018 at two institutions in Japan.

The role of exercise in restoring executive function: a comparison of tobacco-exposed college athletes and sedentary students.

Introduction: As adolescent smoking rates rise, its impact on cognitive function has drawn greater attention. This study explores whether exercise can mitigate the negative effects of smoking on executive function in male college students.

Methods: Sixty male college students were divided into four groups (n = 15 each): sedentary smokers, sedentary nonsmokers, athletic smokers, and athletic nonsmokers.

Virtual reality therapy in managing cancer pain in middle-aged and elderly: a systematic review and meta-analysis.

Background: Virtual reality technology has been proposed to rehabilitate cancer patients. This study aimed to summarize the effectiveness of virtual reality (VR)--based therapies for pain management in middle-aged and elderly cancer patients.

Methods: This meta-analysis was registered in PROSPERO (CRD42023400432).