2 results match your criteria: "School of Public Health of Xinjiang Medicial University[Affiliation]"
[Effects of 2,2',4,4'-tetrabrominated diphenyl ethers on the TRalpha1 and TRbeta1 expression in liver in C57BL/6 mice].
Wei Sheng Yan Jiu
July 2010
School of Public Health of Xinjiang Medicial University, Urumchi 830054, China.
Objective: To study the effect of 2,2',4,4'-tetrabrominated diphenyl ethers (BDE-47) on the expression change of TRalpha1, TRbeta1 at both mRNA and protein levels.
Methods: C57BL/6 mice were divided randomly into 4 groups and administrated with corn oil, 0.5, 5 and 50 mg/kg/BW BDE-47 for 4 days through intraperitoneal injection respectively.
[Effects and toxicity mechanism of 2,2',4,4'-tetrabrominated diphenyl ethers on the homeostasis of thyroid hormone system in C57BL/6 mice].
Wei Sheng Yan Jiu
September 2009
School of Public Health of Xinjiang Medicial University, Urumchi 830054, China.
Objective: To investigate the effects and of toxicity mechanism of 2,2',4,4'-TETRABDE (BDE-47) on TT3, TT4 and TSH in C57BL/6 mice.
Methods: C57BL/6 mice were divided randomly into 4 groups, and given with corn oil (control group) and 1 micromol/(kg x d), 10 micromol/(kg x day) and 100 micromol/(kg x day) BDE-47 for 4 days through intraperitoneal injection respectively. After collecting the bloods, livers and thyroids, the T3, T4 and TSH levels of serum were detected by electro chemiluminescenc (ECLI), thyroid peroxidase (TPO) activities in thyroid by guaiacol method and type-I deiodinase (DI) in liver by CHOPRA method.