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Background And Purpose: High-alert medication is considered to be a medication that presents a high risk of causing significant patient harm when used erroneously and its consequences can be fatal. The Nurses' Knowledge of High-Alert Medication scale (NKHAM) is a tool available to evaluate the knowledge of nurses in practice about this issue.

Aim: This pilot study aimed to measure the reliability and known-groups validity of the Brazilian version of the NKHAM.

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