2 results match your criteria: "School of Medicine at University of Alabama at Birmingham[Affiliation]"
Genetic strategy to decrease complement activation with adenoviral therapies.
PLoS One
February 2020
Department of Otolaryngology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Background: A major obstacle to using recombinant adenoviral vectors in gene therapy is the natural ability of human adenovirus to activate the classical and alternate complement pathways. These innate immune responses contribute to hepatic adenoviral uptake following systemic delivery and enhance the humoral immune responses associated with adenoviral infection.
Methods: A recombinant Ad5 vector was genetically modified to display a peptide sequence ("rH17d'"), a known inhibitor of the classical complement pathway.
Hemorrhage after transoral robotic-assisted surgery.
Otolaryngol Head Neck Surg
July 2013
Department of Surgery, Division of Otolaryngology-Head and Neck Surgery, School of Medicine at University of Alabama at Birmingham, Birmingham, Alabama 35233, USA.
Objective: An increasing number of head and neck surgeons have begun using transoral robotic-assisted surgery. Our objective was to examine the postoperative bleeding complications we have encountered to determine risk factors and to discuss the topic of hemorrhage control.
Study Design: Case series with chart review.