19 results match your criteria: "School of Medicine Wayne State University Detroit[Affiliation]"

Article Synopsis
  • Patients who have undergone solid organ transplants are at higher risk for severe COVID-19 due to immunosuppressive therapy, necessitating better vaccination and treatment strategies.
  • A study assessed the outcomes of liver and kidney transplant recipients diagnosed with COVID-19, focusing on factors like vaccine doses and monoclonal antibody (mAb) therapy.
  • Results showed that while some vaccine doses had no impact, liver transplant patients on mycophenolate had significantly higher mortality rates, and those receiving mAb therapy had lower hospitalization rates, highlighting the need for tailored treatment approaches in this vulnerable group.*
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Idiopathic omental hemorrhage (IOH) is a rare and underexplored entity in current medical literature. Most patients are male, aged 20-65 years, presenting with abdominal pain. Like most presentations of active intra-abdominal bleeding, recognition, stabilization, and definitive management are key.

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Coincidence or association: Adult-onset Still's disease following HPV vaccine.

Clin Case Rep

July 2024

Department of Rheumatology Henry Ford Health Detroit Michigan USA.

This case details adult-onset Still's disease (AOSD) onset post-human papillomavirus (HPV) vaccination and acute gastroenteritis. The timing of HPV vaccine and vaccine-autoimmune disease literature may potentially confound the well-established link between infections and AOSD onset.

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Rheumatoid arthritis (RA) is an autoimmune disorder with a varying range of organs involved leading to adverse outcomes. However, very little is known, with conflicting results about the association between RA and atrial fibrillation (AF). We aim to evaluate the association between RA and AF, and other clinical outcomes.

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Background Heart failure with preserved ejection fraction (HFpEF) is a significant unmet need in cardiovascular medicine and remains an untreatable cardiovascular disease. The role and mechanism of interleukin-1β in HFpEF pathogenesis are poorly understood. Methods and Results C57/Bl6J and interleukin-1β male mice were randomly divided into 4 groups.

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Background: Public health agencies widely adopt social media for health and risk communication. Moreover, different platforms have different affordances, which may impact the quality and nature of the messaging and how the public engages with the content. However, these platform effects are not often compared in studies of health and risk communication and not previously for the COVID-19 pandemic.

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Inference of Onset Age of Preclinical State and Sojourn Time for Breast Cancer.

Med Res Arch

February 2022

Biostatistics and Bioinformatics Core, Karmanos Cancer Institute, Department of Oncology, School of Medicine Wayne State University. Detroit, Michigan 48201.

Aims: Accurate estimation of the three key parameters (sensitivity, time duration in disease-free state and sojourn time in preclinical state) in cancer screening are critical. Likelihood method with a new link function was applied to the Health Insurance Plan of Greater New York (HIP) breast cancer screening data, to estimate the onset age of preclinical state and the sojourn time in the preclinical state for breast cancer.

Materials And Methods: A new link function to model sensitivity as a function of time in the preclinical state and the sojourn time was adopted.

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Understanding the #longCOVID and #longhaulers Conversation on Twitter: Multimethod Study.

JMIR Infodemiology

February 2022

Henry Ford Medical Group Henry Ford Health System Detroit, MI United States.

Background: The scientific community is just beginning to uncover the potential long-term effects of COVID-19, and one way to start gathering information is by examining the present discourse on the topic. The conversation about long COVID-19 on Twitter provides insight into related public perception and personal experiences.

Objective: The aim of this study was to investigate the #longCOVID and #longhaulers conversations on Twitter by examining the combined effects of topic discussion and social network analysis for discovery on long COVID-19.

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This is a case of a 60-year-old man living with HIV who presented with advanced cutaneous squamous cell carcinoma. After workup, medical and surgical treatment, and disease recurrence, he achieved a complete response with no unexpected toxicities after immunotherapy with cemiplimab.

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Subclavian steal syndrome is a vascular disorder that consists of significant blood supply restriction with resultant insufficiency of the vertebrobasilar artery and the subclavian artery causing symptomatic insufficiency to the brain and upper extremity. It is important to recognize this condition in patients with subacute to chronic posterior circulation vascular insufficiency as early diagnosis and treatment can have good clinical outcomes (J Clin Neurosci. 2010;:1339).

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Acute cardiogenic pulmonary edema is a highly unstable and potentially lethal condition that is most commonly associated with markedly elevated blood pressure (BP). Use of nitrates, diuretics, and non-invasive positive pressure ventilatory support are the mainstays of early intervention and stabilization. Use of high-dose bolus intravenous nitroglycerin, which causes both preload and afterload reduction, has shown significant promise in studies to date, reducing the need for endotracheal intubation (ETI) and intensive care unit admission.

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Palatal myoclonus can be primary or secondary. In primary palatal myoclonus, no obvious structural brain lesions can be found within the triangle of Guillain and Mollaret. Common causes of secondary myoclonus include stroke, demyelination, infections, trauma, and neurodegeneration.

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Article Synopsis
  • Proton pump inhibitors (PPIs) can cause acute interstitial nephritis and autoimmune hemolytic anemia at the same time.
  • If these conditions arise, it's important to stop using the PPI immediately.
  • Careful management of PPI prescriptions is crucial; they should only be used when necessary and discontinued when they're no longer needed.
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Electrodiagnostic Evidence of Berrettini Anastomosis.

J Clin Neurophysiol

March 2018

Department of Physical Medicine and Rehabilitation, Michigan State University, College of Osteopathic Medicine, East Lansing, Michigan, U.S.A.

Purpose: Cadaveric palmar dissections reveal an ulnar sensory crossover (Berrettini anastomosis) to the third common palmar nerve so frequently that this crossover is considered a normal part of the anatomy. No literature has documented electrophysiologic evidence of the Berrettini anastomosis (BA). Presentation of third digit ulnar sensory crossover waveforms.

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Objective: Providing effective dietary counselling so that pregnancy weight gain remains within the 2009 Institute of Medicine (IOM) guidelines requires accurate maternal energy intake measures. Current practice is based on self-reported intake that has been demonstrated unreliable. This study applies an objective calculation of energy intake from a validated mathematical model to identify characteristics of individuals more likely to misreport during pregnancy.

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In recent years the problem of how inter-individual differences play a role in risk-taking behavior has become a much debated issue. We investigated this problem based on the well-known balloon analog risk task (BART) in 48 healthy subjects in which participants inflate a virtual balloon opting for a higher score in the face of a riskier chance of the balloon explosion. In this study, based on a structural Voxel Based Morphometry (VBM) technique we demonstrate a significant positive correlation between BART score and size of the gray matter volume in the anterior insula in riskier subjects.

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