743 results match your criteria: "School of Medicine Tokyo Japan.[Affiliation]"
Background: We aimed to quantify the incidence of atrial fibrillation (AF) in patients with cryptogenic stroke globally, as well as separately in patients in and outside of Japan, using an implantable loop recorder from a prospective, observational, Reveal LINQ Registry.
Methods And Results: Patients developing cryptogenic stroke and monitored by implantable loop recorder for searching AF were studied. The primary end point was incidence of AF within 36 months after insertion.
Background: The Clinical Frailty Scale (CFS) is a useful frailty marker for predicting clinical outcomes in patients undergoing invasive therapy. However, the clinical impact of CFS after transcatheter edge-to-edge repair in patients with mitral regurgitation (MR) remains unclear. This study aimed to elucidate the association between the baseline frail status defined by the CFS and clinical outcomes with or without postprocedural MR ≥2+ (post-MR ≥2+) after transcatheter edge-to-edge repair.
View Article and Find Full Text PDFIsolated unilateral absence of the pulmonary artery (IUAPA) presenting with progressive interstitial shadows: A case report.
Respirol Case Rep
October 2024
Unilateral absence of the pulmonary artery (UAPA) is a rare congenital condition. When UAPA occurs without associated congenital heart disease, it is referred to as isolated unilateral absence of the pulmonary artery (IUAPA). IUAPA is frequently not diagnosed until adulthood.
View Article and Find Full Text PDFArticle Synopsis
- The Japanese Catheter Ablation (J-AB) registry, launched in August 2017, is a nationwide voluntary study led by the Japanese Heart Rhythm Society focused on collecting data about catheter ablation procedures.
- In January 2022, the registry's data collection system shifted from REDCap to the Fountayn system to improve data management.
- By the end of 2022, the registry compiled data from 90,042 procedures across 614 hospitals, highlighting the types of arrhythmias, outcomes, and complications, with participants averaging 66.7 years old and 65.9% being male.
Objectives: Few reports have detailed improvements in the quality of colonoscopies with continuous training post-fellowship completion. We examined the changes in colonoscopy performance among trainees during our advanced endoscopy training program.
Methods: Screening or surveillance colonoscopies performed by 11 trainees who participated in our 3-year advanced endoscopy training program between April 2015 and March 2020 were retrospectively analyzed.
Infective endocarditis due to nasal septal perforation during home oxygen therapy.
Respirol Case Rep
October 2024
Division of Respiratory Diseases, Department of Internal Medicine The Jikei University School of Medicine Tokyo Japan.
Article Synopsis
- A 64-year-old man on home oxygen therapy developed infective endocarditis (IE) linked to a nasal septal perforation, causing respiratory issues.
- Methicillin-sensitive Staphylococcus aureus (MSSA) was found repeatedly in blood cultures and also isolated from the patient's nasal cavity.
- Despite treatment with antibiotics, he later suffered from aspiration pneumonia and died, highlighting the importance of proper nasal care to prevent severe infections during home oxygen therapy.
Background: Dextromethorphan (DXM) is an over-the-counter drug that is commonly abused by teenagers. Its main pharmacological property is a low-affinity -methyl-d-aspartate (NMDA) receptor antagonist.
Case Presentation: We report acute psychotic dissociation induced by DXM and alcohol in a patient with alcohol dependence, which made it difficult to distinguish alcohol withdrawal symptoms with limited information.
Aim: The aim of this study was to develop quantitative outcome indicators for psychiatric training programs integrated into the General Medicine In-Training Examination (GM-ITE) and to investigate which characteristics correlate with high scores in psychiatry.
Methods: A nationwide cross-sectional study was conducted over 3 fiscal years (2021-2023). An anonymous online questionnaire was distributed to postgraduate year 1 and 2 residents who completed the GM-ITE.
Article Synopsis
- * He was initially treated with corticosteroids but developed refractory pneumothorax, which made managing the air leakage challenging.
- * The treatment was successfully modified to include mepolizumab, an anti-interleukin-5 therapy, and an endobronchial Watanabe spigot, resulting in the resolution of the pneumothorax and no recurrence of EP post-treatment.
From Optional to Default - Enhancing Article Viewership Through X (Formerly Twitter) Posting.
Circ Rep
September 2024
Information and Communication Committee, the Japanese Circulation Society Tokyo Japan.
Article Synopsis
- * Researchers analyzed X-posting rates and journal viewership data from April 2022 to September 2023, noting a significant increase in both after protocol changes made in March 2023.
- * The findings suggested that adopting the new X-posting strategy led to more article views, indicating a positive impact on viewer access.
Training potential of a teleoperated humanoid robot for use by a young psychiatrist during childcare leave.
PCN Rep
September 2024
Department of Neuropsychiatry, Graduate School of Biomedical Sciences Nagasaki University Nagasaki Japan.
Article Synopsis
- - The study highlights how childcare leave can hinder the training of early-career psychiatrists in Japan, leading to the development of a teleoperated robot system (Sota) that allows them to learn remotely while on leave.
- - A case study is presented where a young psychiatrist used Sota to observe and communicate with a board-certified psychiatrist during a patient examination, enhancing her learning about Tourette's syndrome while at home.
- - The findings indicate that this teleoperated system is beneficial for ongoing professional development during childcare leave, and future research is encouraged to further assess its effectiveness and impact over time.
Article Synopsis
- Achalasia is a rare condition where the lower esophageal sphincter doesn't relax properly, leading to difficulty swallowing, and the main treatment options are Laparoscopic Heller Myotomy (LHM) and Peroral Endoscopic Myotomy (POEM).
- Recent studies indicate that both LHM and POEM show similar long-term success rates after 5 years, but patients who undergo POEM are more likely to experience gastroesophageal reflux disease (GERD) than those who have LHM.
- The choice of treatment can depend on the type of achalasia, and while some evidence suggests POEM might be better for type III patients, more research is needed for long-term results and to tailor treatments to individual patient
The prognostic impact of perioperative dynamic changes in cachexia index in patients with hepatocellular carcinoma.
Ann Gastroenterol Surg
September 2024
Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery The Jikei University School of Medicine Tokyo Japan.
Article Synopsis
- The study investigates the cachexia index (CXI), a measure incorporating skeletal muscle, inflammation, and nutritional status, and its impact on the prognosis of patients with hepatocellular carcinoma (HCC) after liver surgery.
- Researchers analyzed 131 patients who had primary liver resections between 2008 and 2019, assessing preoperative and postoperative CXI to determine its correlation with disease-free and overall survival rates.
- Results indicated that both low preoperative and postoperative CXI levels, along with various clinical factors like tumor characteristics and complications, significantly predicted patient survival, suggesting that monitoring CXI changes could provide valuable prognostic information.
Risk model for morbidity and mortality following liver surgery based on a national Japanese database.
Ann Gastroenterol Surg
September 2024
The Japanese Society of Gastroenterological Surgery Tokyo Japan.
Article Synopsis
- The study aimed to assess the health risks and death rates associated with liver surgery in Japan and create a predictive risk model using national data.
- Researchers analyzed data from 73,861 patients who underwent liver surgery from 2014 to 2019, focusing on short-term outcomes like mortality and complications.
- Key findings showed low mortality rates of 0.9% in 30 days and 1.7% in hospitals, with certain surgery types and patient conditions significantly increasing the risk of complications and death; the newly developed risk model effectively predicts these outcomes.
Effects of the COVID-19 pandemic on short-term postoperative outcomes of emergency surgery for gastroduodenal perforation: A nationwide study in Japan based on the National Clinical Database.
Ann Gastroenterol Surg
September 2024
The Japan Surgical Society Tokyo Japan.
Article Synopsis
- * Analyzed data from nearly 8,000 cases between 2019 and 2021 showed only minor increases in mortality and complications, with one significant spike in complications in July 2020.
- * Overall, the pandemic had limited negative impacts on surgical outcomes, indicating that Japan's emergency surgical system for gastroduodenal perforation remained effective throughout this period.
Article Synopsis
- The study aimed to assess the effects of the COVID-19 pandemic on pancreatic cancer surgeries, specifically pancreaticoduodenectomy, in Japan.
- Researchers analyzed data from 22,255 patients over several years, determining that the number of surgeries actually increased, despite the pandemic's challenges.
- Findings indicated that complication and mortality rates remained stable and within normal ranges, suggesting that the healthcare system effectively managed pancreatic cancer treatment during the pandemic.
Peritoneal lavage cytology in patients with curative resection for stage II and III colorectal cancer: A multi-institutional prospective study.
Ann Gastroenterol Surg
September 2024
Division of Molecular and Diagnostic Pathology Niigata University, Graduate School of Medical and Dental Sciences Niigata Japan.
Aim: To clarify the usefulness of intraoperative lavage cytology in patients undergoing curative resection for pStage II-III colorectal cancer in a prospective multicenter study.
Methods: Patients preoperatively diagnosed with stage II-III colorectal cancer between 2013 and 2017 from 20 hospitals were enrolled. Lavage cytology was performed twice during the surgery.
Low incidence of pancreatic fistula and well-preserved endocrine function with non-reconstructed small remnant pancreas after pancreaticoduodenectomy.
Ann Gastroenterol Surg
September 2024
Aim: Pancreatic reconstruction after pancreaticoduodenectomy (PD) that leaves a small remnant pancreas is often difficult. Pancreatic fistula is a major complication after PD, and fistulas are rare in patients with hard pancreas. However, the clinical impact of non-reconstructed small remnant after PD with hard pancreas is unknown.
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- A multicenter study assessed the safety and mid-term outcomes of classical laparoscopic and endoscopic cooperative surgery (LECS) for treating gastric submucosal tumors (G-SMTs) following national health insurance coverage.
- The study involved 201 patients across 21 institutions from April 2014 to March 2016, identifying classical LECS as the most common procedure performed, with a good resection rate and manageable complications.
- Results indicated that while most surgeries had favorable outcomes, postoperative complications occurred in 5% of cases, emphasizing the general effectiveness of these methods in clinical practice.
Article Synopsis
- The study aimed to assess the safety and effectiveness of propofol sedation in complex endoscopic procedures like endoscopic cholangiopancreatography, focusing on risk factors for excessive sedation.
- A review of 870 patient cases highlighted sedation-related issues, revealing rates of excessive sedation (7.8%), hypoxemia (6.0%), and hypotension (1.8%), with obesity and sleep apnea significantly linked to higher sedation risks.
- The findings suggest that sedation strategies for these patients should be personalized, especially for those with identified risk factors such as obesity and prolonged procedure times.
Introduction: Although uterine perforation is a rare but serious complication, intrauterine devices are globally popular and effective contraceptive methods.
Case Presentation: A 76-year-old female patient manifesting symptoms of vaginal leakage and lower abdominal discomfort was admitted to our hospital. Diagnostic imaging identified a vesicovaginal fistula and bladder calculi attributable to perforation of the bladder by an intrauterine device that had been inserted over four decades ago.
Introduction: BRAF mutations in bladder cancer are rare. MEK inhibitors have excellent clinical benefits in the treatment of melanoma.
Case Presentation: A 60-year-old male was diagnosed with muscle-invasive bladder cancer and underwent total cystectomy and ileal conduit diversion.
Introduction: We report a case of rectal perforation following SpaceOAR placement utilized with iodine-125 low-dose-rate brachytherapy for prostate cancer.
Case Presentation: A 65-year-old patient with localized prostate cancer underwent SpaceOAR placement following LDR-BT. No significant issues occurred with the SpaceOAR procedure, and no abnormalities were found on the next day's T2-weighted magnetic resonance imaging.
Introduction: Transplant renal vein thrombosis is a serious post-transplant complication. We report a case in which a thrombus was found in the transplant renal vein and rescued the transplanted kidney utilizing interventional radiology.
Case Presentation: A 56-year-old woman underwent ABO-compatible living donor renal transplantation due to impaired renal function caused by IgA nephropathy.
Article Synopsis
- Atomoxetine, a medication for ADHD, can cause serious cardiac complications if overdosed, leading to cases like the one presented here involving venoarterial extracorporeal membrane oxygenation (VA-ECMO) for life-threatening cardiogenic shock.
- A 30-year-old male experienced seizures and severe circulatory failure after a significant atomoxetine overdose, requiring emergency VA-ECMO for resuscitation, alongside other treatments like medication removal and intravenous lipid emulsion.
- The case highlights the need for healthcare providers to be aware of the potentially severe cardiac effects of atomoxetine overdose and underscores the importance of close monitoring and intensive care for patients in critical condition.