12 results match your criteria: "School of Medicine (A.G.[Affiliation]"

B-Cell Immune Checkpoints Come of Age in Cardio-oncology.

Circ Res

March 2024

Section of Cardio-Oncology and Immunology, Cardiovascular Research Institute (CVRI), University of California San Francisco, School of Medicine (A.G., J.M.).

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  • Vertebral compression fractures are common in older adults, and this study compares the effectiveness and safety of three surgical treatments: balloon kyphoplasty, vertebroplasty, and SpineJack vertebral implant.
  • A multi-institutional review analyzed outcomes from 344 procedures, focusing on pain relief, restoration of vertebral body height, and changes in spinal curvature, assessing complications within 90 days post-surgery.
  • Results showed significant pain improvement across all treatments, but the SpineJack implant led to better outcomes in terms of worst pain, vertebral height restoration, and alignment than both kyphoplasty and vertebroplasty.
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  • Renin suppression in primary aldosteronism is linked to kidney damage due to high aldosterone levels, and reversing this suppression through treatment may improve renal health.
  • A study analyzed data from 318 patients treated with mineralocorticoid receptor antagonists to see if restoring renin levels affects kidney function over time.
  • Results showed that patients who managed to reverse renin suppression experienced a slower decline in kidney function compared to those who remained suppressed, suggesting that proper treatment may help protect the kidneys.
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In the Dobbs decision the United States Supreme Court overturned Roe v. Wade, returning the issue of abortion to the states. To date, there is little published data on the impact this might have on where future residents choose to pursue graduate medical education.

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Pediatric trauma in the California-Mexico border region: Injury disparities by Area Deprivation Index.

J Trauma Acute Care Surg

May 2022

From the Division of Pediatric Surgery, Department of Surgery (A.G.S., R.C.I.), University of California San Diego, Rady Children's Hospital San Diego; Naval Medical Center San Diego (A.G.S.); Scripps Mercy Hospital San Diego (A.S.R., M.J.M., V.B., M.J.S.); Rady Children's Hospital San Diego (K.S.); and University of California San Diego School of Medicine (A.G.A., C.B.G.), San Diego, California.

Background: The California-Mexico border region is a high-volume trauma area with populations of widely disparate socioeconomic status. This work analyzed differences in demographics and mechanism of injury in children using the Area Deprivation Index (ADI), a composite measure of 17 markers of neighborhood socioeconomic disadvantage.

Methods: A retrospective review was performed of pediatric patients evaluated at the regional Level I Pediatric Trauma Center between 2008 and 2018.

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Misusing Public Health as a Pretext to End Asylum - Title 42.

N Engl J Med

April 2022

From the Department of Medicine, Boston University School of Medicine (A.G.B.), Partners In Health (L.V., J.M.), the Department of Global Health and Social Medicine, Harvard Medical School (J.M.), and the Division of Global Health Equity, Department of Medicine, Brigham and Women's Hospital (J.M.) - all in Boston; Zanmi Lasante, Port-au-Prince, Haiti (L.V.); Physicians for Human Rights, New York (M.H.); and the Department of Internal Medicine, University of Michigan Medical School, and the University of Michigan School of Public Health - both in Ann Arbor (M.H.).

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Recovery From COVID-19 in Multiple Sclerosis: A Prospective and Longitudinal Cohort Study of the United Kingdom Multiple Sclerosis Register.

Neurol Neuroimmunol Neuroinflamm

January 2022

From the Mental Health and Clinical Neurosciences Academic Unit, School of Medicine (A.G., N.E.), University of Nottingham; Clinical Neurology (A.G., N.E.), Nottingham University Hospitals NHS Trust; Population Data Science (R.M.M.), Swansea University Medical School; and Department of Cellular and Molecular Neuroscience (R.N.), Imperial College London, United Kingdom.

Background And Objectives: To understand the course of recovery from coronavirus disease 2019 (COVID-19) among patients with multiple sclerosis (MS) and to determine its predictors, including patients' pre-COVID-19 physical and mental health status.

Methods: This prospective and longitudinal cohort study recruited patients with MS who reported COVID-19 from March 17, 2020, to March 19, 2021, as part of the United Kingdom MS Register (UKMSR) COVID-19 study. Participants used online questionnaires to regularly update their COVID-19 symptoms, recovery status, and duration of symptoms for those who fully recovered.

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Lipid uptake and metabolism are central to the function of organs such as heart, skeletal muscle, and adipose tissue. Although most heart energy derives from fatty acids (FAs), excess lipid accumulation can cause cardiomyopathy. Similarly, high delivery of cholesterol can initiate coronary artery atherosclerosis.

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Despite decades of improvement in the quality and outcomes of cardiovascular care, significant gaps remain. Existing quality improvement strategies are often limited in scope to specific clinical conditions and episodic care. Health services and outcomes research is essential to inform gaps in care but rarely results in the development and implementation of care delivery solutions.

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Volumetric MRI Study of the Brain in Fetuses with Intrauterine Cytomegalovirus Infection and Its Correlation to Neurodevelopmental Outcome.

AJNR Am J Neuroradiol

February 2019

From the Antenatal Diagnostic Unit (A.G., E.K., D.H., R.B., S.L.), Department of Obstetrics and Gynecology.

Background And Purpose: In recent years, effort has been made to study 3D biometry as a method for fetal brain assessment. In this study, we aimed to compare brain volumes of fetuses with cytomegalovirus infection and noninfected controls. Also, we wanted to assess whether there is a correlation to their neurodevelopmental outcome as observed after several years.

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Inspiratory and expiratory muscle training in subacute stroke: A randomized clinical trial.

Neurology

August 2015

From the Rehabilitation Research Group (M.M.-S., A.G.-S., E.D., M.-C.B., F.E., E.M.) and the Muscle and Respiratory System Research Unit (URMAR) (D.A.R., E.B.), Institut Hospital del Mar d'Investigacions Mèdiques (IMIM); the Physical Medicine and Rehabilitation Department (M.M.-S., A.G.-S., M.D., E.D., M.-C.B., F.E., E.M.), Parc de Salut Mar (Hospital del Mar, Hospital de l'Esperança); the School of Medicine (A.G.-S., E.D., D.A.R., F.E., E.M.), Universitat Autònoma de Barcelona; the Respiratory Medicine Department (D.A.R., E.B., M.O.-L.), Hospital del Mar; the Department of Health Sciences (CEXS) (D.A.R., E.B., M.O.-L.), Universitat Pompeu i Fabra, Barcelona; and the Centro de Investigación en Red de Enfermedades Respiratorias (CIBERES) (D.A.R., E.B.), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.

Objective: To assess the effectiveness, feasibility, and safety of short-term inspiratory and expiratory muscle training (IEMT) in subacute stroke patients.

Methods: Within 2 weeks of stroke onset, 109 patients with a first ischemic stroke event were randomly assigned to the IEMT (n = 56) or sham IEMT (n = 53) study group. The IEMT consisted of 5 sets of 10 repetitions, twice a day, 5 days per week for 3 weeks, at a training workload equivalent to 30% of maximal respiratory pressures.

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