Colorimetric detection of microRNA miR-21 based on nanoplasmonic core-satellite assembly.

In order to detect microRNAs (miRNAs), we developed a colorimetric sensing method on the basis of the plasmonic coupling effect. Gold nanoplasmonic particles (GNPs) are assembled in a core-satellite configuration in the presence of target miRNA, inducing remarkable changes in the scattering color and spectra at the picomolar level with selectivity.

To bin or not to bin? The effect of CT system limiting resolution on noise and detectability.

We examine the noise advantages of having a computed tomography (CT) detector whose spatial resolution is significantly better (e.g. a factor of 2) than needed for a desired resolution in the reconstructed images.