Assessing spinel zinc ferrite nanoparticles in aquatic ecosystems: Toxic threat or beneficial detoxifier for aquatic life?

The effectiveness of magnetic nanoparticles in removing pollutants during water treatment is well established, but their introduction into aquatic ecosystems raises significant toxicity concerns. This study investigates the histological and physiological effects of zinc ferrite magnetic nanoparticles (ZnFeOMNPs) on the Mediterranean mussel (Mytilus galloprovincialis) and examines the impact of concurrent exposure to these nanoparticles and the insecticide thiomethoxam (TMX). Mussels were exposed to nominal concentrations of ZnFeOMNPs (1, 10, 100 mg/L) both individually and with TMX.

mHealth knowledge and usage in maternal healthcare delivery: perspectives and experiences of healthcare practitioners in Ghana.

Objectives: This study explored the knowledge and experiences of health practitioners regarding the use of mobile health (mHealth) for maternal healthcare delivery.

Design: Underpinned by the Unified Theory of Acceptance and Use of Technology, this study was an exploratory qualitative design involving in-depth interviews. Data collection occurred between July 2023 and January 2024.

Association of falls with risk of dementia and all-cause mortality: a cohort study of Japanese older adults with a 9-year follow-up.

Objective: Many risk factors affect dementia and all-cause mortality. However, whether falls are a risk factor for dementia and all-cause mortality is unclear. The study examines the association of falls with the risk of dementia and all-cause mortality, and whether dementia mediates the association of falls with all-cause mortality.

Mechanisms of mitochondrial damage-associated molecular patterns associated with inflammatory response in cardiovascular diseases.

Cardiovascular diseases (CVDs) continue to be a substantial global healthcare burden despite considerable progress in therapies. The inflammatory response during the progression of CVD has attracted considerable attention. Mitochondria serve as the principal energy source for the heart.

What Do Mothers Know About Nutrition? Impacts on Childhood Nutrition Outcomes in Sub-Saharan Africa.

Introduction: Globally, the prevalence of undernutrition is highest in the sub-Saharan African region with over a third of the world's stunted children residing in this region. Many studies have explored child nutrition in sub-Saharan Africa, but they often overlook the intricate nuances of maternal knowledge. We examined the association between maternal nutritional knowledge and childhood nutritional outcomes.

Why is learning from patient safety incidents (still) so hard? A sociocultural perspective on learning from incidents in healthcare organizations.

Purpose: Despite robust quality improvement efforts in healthcare, learning from patient safety incidents remains difficult. Our study explores counter-vailing powers shaping learning processes and possibilities in healthcare organizations, with a focus on social, political and organizational dynamics of learning.

Design/methodology/approach: Deploying concepts of situated curriculum, boundary work and interconnected knowledge practices, we interviewed staff and physicians ( = 15) in a large Academic Health Science Centre in Canada about their experiences of incident investigations and resultant information sharing.

Prevalence and contributors to anaemia among children aged 6 to 59 months in Kyangwali Refugee settlement, Western Uganda: a cross-sectional study.

Background: Anaemia is a major cause of morbidity among children under five years in Uganda. However, its magnitude among refugee populations is marginally documented. In this study, the prevalence and contributors to anaemia among children 6 to 59 months in Kyangwali refugee settlement in Western Uganda was determined.

Restricted Daily Exposure of Environmental Enrichment: Bridging the Practical Gap from Animal Studies to Human Application.

Daily restricted environmental enrichment (REE) refers to limited, structured periods of enrichment aimed at improving both physical and cognitive well-being in animals and humans. This review explores the significance of REE, focusing on studies that investigate 2 and 3 h daily enrichment protocols. Through an analysis of 21 key studies, this paper highlights how even brief periods of REE can lead to substantial improvements in brain plasticity, cognitive function, and stress resilience.

Heptamethine cyanine-based polymeric nanoparticles for photothermal therapy in HCT116 human colon cancer model.

In this work, we synthesize a quinoline-based heptamethine cyanine, QuCy7, with sulfonate groups to enhance water solubility. This dye demonstrates exceptional near-infrared absorption beyond 750 nm, accompanied by photothermal properties but low photostability. Encapsulating QyCy7 with polyethylene glycol to form nanopolymer, QuCy7@mPEG NPs, addresses the issue of its photoinstability.

Executive Function Strengths in Athletes: a Systematic Review and Meta-Analysis.

Objective: Whether athletes possess superior executive functions still needs further examination. Therefore, the aim of this study is to explore the executive function advantages of athletes and the differences in these advantages between open- and closed-skill sports through systematic review and meta-analysis.

Methods: Computer searches of CNKI, Web of Science, PubMed, ScienceDirect, and SPORTDiscus databases were conducted.

Investigating students' intention to utilize an e-learning platform in an aviation institution during the COVID-19 pandemic.

Aviation College is a higher education institution that shifted to e-Learning as the education platform during the COVID-19 Pandemic. This shift has posed challenges, especially in developing countries like the Philippines. This study aims to evaluate students' intentions toward using an e-learning platform at a collegiate aviation institution during the pandemic by employing an integrated extended Technology Acceptance Model (TAM) and Seddon's Information System (IS) Success Model.

Artificial intelligence and sexual reproductive health and rights: a technological leap towards achieving sustainable development goal target 3.7.

Target 3.7 of the Sustainable Development Goals (SDGs) aims for universal access to sexual and reproductive health (SRH) services by 2030, including family planning services, information, education, and integration into national strategies. In contemporary times, reproductive medicine is progressively incorporating artificial intelligence (AI) to enhance sperm cell prediction and selection, in vitro fertilisation models, infertility and pregnancy screening.

Delving into female breast cancer: Distinct disease-specific survival outcomes between invasive lobular and ductal carcinomas revealed by propensity score matching.

Purpose: The difference in prognosis between invasive lobular carcinoma (ILC) and invasive ductal carcinoma (IDC) is still controversial in the academic community. Resolving this controversy can help to more accurately determine patients' prognosis, provide further personalized treatment, alleviate unnecessary psychological burden for some patients, and provide direction for further fundamental research.

Patients And Methods: A retrospective cohort study was conducted using the SEER Research Plus Data 8 Registries, Nov 2021 sub (1978-2019), including female breast cancer patients diagnosed with ILC or IDC between 2010 and 2015.

Investigating factors influencing the donation intentions and volunteering intentions for the 2023 Turkey earthquake victims.

The 2023 Turkey earthquake, one of the most devastating natural disasters in recent history, highlighted the need to understand factors driving public support. This study aimed to explore the determinants of donation and volunteer intentions for earthquake victims by integrating Protection Motivation Theory and the Extended Theory of Planned Behavior. Using a convenience sampling approach, an online questionnaire with 76 items was distributed to 509 voluntary respondents.

The immune regulatory role of exosomal miRNAs and their clinical application potential in heart failure.

Heart failure (HF) is a complex and debilitating condition characterized by the heart's inability to pump blood effectively, leading to significant morbidity and mortality. The abnormality of immune response is a key factor in the progression of HF, contributing to adverse cardiac remodeling and dysfunction. Exosomal microRNAs (miRNAs) play a pivotal role in regulating gene expression and cellular function, which are integral to the crosstalk between cardiac and immune cells, influencing immune cell functions, such as macrophage polarization, T cell activity, and cytokine production, thereby modulating various pathological processes of HF, such as inflammation, fibrosis, and cardiac dysfunction.

Quadriceps tendon autograft diameters are routinely above 8 mm, and preoperative size estimation before anterior cruciate ligament reconstruction may not be necessary for this graft type: A systematic review.

Purpose: To identify values of reported quadriceps tendon (QT) autograft diameter and length in anterior cruciate ligament reconstruction (ACLR), and to identify methods to predict these parameters.

Methods: A search was conducted across three databases from inception to 30 March 2024. Data on study characteristics, demographics, anthropometric data, imaging techniques, and QT autograft or harvested QT tendon parameters were extracted.

Sensor-Based Frailty Assessment Using Fitbit.

This study evaluated the reliability of Fitbit in assessing frailty based on motor and heart rate (HR) parameters through a validated upper extremity function (UEF) test, which involves 20 s of rapid elbow flexion. For motor performance, participants completed six trials of full elbow flexion using their right arm, with and without weight. Fitbit and a commercial motion sensor were worn on the right arm.

Left Ventricular and Atrial Function Analysis Following Transcatheter Edge-to-Edge Mitral Valve Repair.

Conventional echocardiography used to assess volumes of the left ventricle (LV) and left atrium (LA) along with mitral regurgitation grade is routine in studies before and after transcatheter edge-to-edge mitral valve repair (Mitral TEER). Previous studies focus on LV parameter changes and comparison of the functions before and a few months following Mitral TEER implantation, as well as LA reverse remodeling, by assessing LV volumes. However, less is known regarding LA strain changes in the early phase after the procedure.

The Role of Fetuin-A in Tumor Cell Growth, Prognosis, and Dissemination.

Fetuin-A, also known as alpha-2-Heremans-Schmid-glycoprotein (Ahsg), is a multifunctional molecule with diverse roles in biological processes such as mineralization, tumor growth, and inflammation. This review explores the involvement of Ahsg in various cancers, including liver, breast, prostate, colorectal, brain, osteosarcoma, and lung cancers. In many cancer types, Ahsg promotes tumor growth, invasion, and metastasis through various mechanisms, including cellular adhesion, spreading, chemotaxis, and modulation of cell-growth signaling pathways.

Uterine fibroids show evidence of shared genetic architecture with blood pressure traits.

Uterine leiomyomata (fibroids, UFs) are common, benign tumors in females, having an estimated prevalence of up to 80%. They are fibrous masses growing within the myometrium leading to chronic symptoms like dysmenorrhea, abnormal uterine bleeding, anemia, severe pelvic pain, and infertility. Hypertension (HTN) is a common risk factor for UFs, though less prevalent in premenopausal individuals.

Factors related to type 2 diabetic retinopathy and their clinical application value.

Objective: To compare the differences in clinical-related factors between patients with type 2 diabetes (T2DM) and those without diabetic retinopathy (DR) and to explore the risk factors or protective factors affecting DR in T2DM patients.

Methods: We performed a retrospective analysis of 380 patients with type 2 diabetes admitted to Handan Central Hospital from June 2023 to May 2024. Clinical data collected included baseline characteristics, hematological tests, metabolic indicators, and information on diabetic complications and comorbidities.

Acupuncture reduces sedative and anaesthetic consumption and improves pain tolerance in patients undergoing colonoscopy: a Meta-analysis.

Objective: To evaluate the effects of acupuncture anesthesia on the consumption of sedatives and anesthetics, pain, and time consumption in patients undergoing colonoscopy, thus providing evidence that acupuncture anesthesia should be extended to endoscopists and anesthetists.

Methods: Four English and four Chinese databases were searched for randomised controlled trials of acupuncture anaesthesia in patients undergoing colonoscopy, published from database inception to 1 March 2023. Outcomes were consumption of sedatives and anaesthetics, pain tolerance, visual analog scale (VAS) score, the meantime consumption of examination, satisfaction, and adverse reactions.