Risk of intrafascicular spread after deliberate ex vivo intraneural injections of brachial plexus nerve roots.

Background: We investigated the intraneural spread of injected fluid in brachial plexus nerve roots, examining the potential for intrafascicular spread and identifying influencing factors.

Methods: Twelve deliberate ultrasound-guided intraneural injections were performed at the ventral rami of the brachial plexus nerve roots at their exits from the neuroforamina in six fresh, unembalmed, cryopreserved human cadavers. A 22-G, 30-degree bevel echogenic regional anaesthesia needle was used.

Oleogelation for saturated fat replacement in vegan cheese.

Oleogelation was investigated to reduce the saturated fat content of vegan cheese. Oleogels were formulated using a range of oleogelators, oleogelator concentrations and oil phase compositions to study the effect that adjusting these parameters had on both oleogel and vegan cheese properties. Comparing oleogels at an equivalent mass basis of 20 wt%, phytosterol oleogels exhibited greater hardness (5.

Novel Hierarchical Disordered Li- and Al-KIL-2 Catalysts for the Pyrolysis of Biomass Model Compounds and Wool Waste: A Comparison with ZSM-5.

In this study, we investigated the pyrolysis of cellulose, lignin, phenylalanine and textile wool waste using microscale thermogravimetric analysis (TGA) and a gram-scale fixed bed reactor. The pyrolysis was conducted at 500 °C and 1 bar N, using Al- and Li-doped mesoporous KIL-2 and ZSM-5 catalysts for comparison. Our results show that amorphous Al-KIL-2 catalyst was the most efficient in producing aromatics from cellulose and lignin.

Excitation of filamentous growth in Dekkera spp. by quorum sensing aromatic alcohols 2-phenylethanol and tryptophol.

Fungi from the genus Dekkera, also known as Brettanomyces, are significant contaminants in commercial beer and wine production, and when present unintentionally, these non-domesticated yeasts result in the development of undesirable sensorial characteristics, in part due to the production of volatile phenols and acetate esters. The persistence of Dekkera spp. in industrial manufacturing environments can be attributed to its strong bioadhesive properties, allowing it to attach to various surfaces and form biofilms, which often contribute to recurrent contaminations.

Deposition simulations of realistic dosages in patient-specific airways with two- and four-way coupling.

Inhalers spray over 100 million drug particles into the mouth, where a significant portion of the drug may deposit. Understanding how the complex interplay between particle and solid phases influence deposition is crucial for optimising treatments. Existing modelling studies neglect any effect of particle momentum on the fluid (one-way coupling), which may cause poor prediction of forces acting on particles.

Topological phase transition and surface states in a non-Abelian charged nodal line photonic crystal.

Topological charges of nodal lines in a multigap system are represented by non-Abelian numbers, and the Euler class, a topological invariant, can be used to explain their topological phase transitions, such as pair-annihilation of nodal lines. Up until now, no discussion of phase transitions of nodal lines in photonic crystals using the Euler class has been reported, despite the fact that the Euler class and topological phase transition have recently been addressed in metallic or acoustic crystals. Here, we show how the deformation of a photonic crystal causes topological phase transitions in the nodal lines, and the Euler class can be used to theoretically predict the nodal lines' stability based on the non-Abelian topological charge theory.

Isolobal Cationic Iridium Dihydride and Dizinc Complexes: A Dual Role for the ZnR Ligand Enhances H Activation.

The reaction of [Ir(IPr)H][BAr] (; IPr = 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene; BAr = B{CH(3,5-CF)}) with ZnMe proceeds with CH elimination to give [Ir(IPr)(IPr')(ZnMe)H][BAr] (, where (IPr') is a cyclometalated IPr ligand). reacts with H to form tetrahydride [Ir(IPr)(ZnMe)H][BAr], , that loses H under forcing conditions to form [Ir(IPr)(ZnMe)H][BAr], . Crystallization of also results in the formation of its noncyclometalated isomer, [Ir(IPr)(ZnMe)][BAr], , in the solid state.

Guarantees on the structure of experimental quantum networks.

Quantum networks connect and supply a large number of nodes with multi-party quantum resources for secure communication, networked quantum computing and distributed sensing. As these networks grow in size, certification tools will be required to answer questions regarding their properties. In this work we demonstrate a general method to guarantee that certain correlations cannot be generated in a given quantum network.

SmartHypnos: An Android application for low-cost sleep self-monitoring and personalized recommendation generation.

Background And Objective: Sleep is an essential biological function that is critical for a healthy and fulfilling life. Available sleep quality assessment tools contain long questionnaires covering a long period of time, not taking into account daily physical activity patterns and individual lifestyles.

Methods: In this paper we present SmartHypnos, an Android application that supports low-end devices.

A Novel Non-Contact Multi-User Online Indoor Positioning Strategy Based on Channel State Information.

The IEEE 802.11bf-based wireless fidelity (WiFi) indoor positioning system has gained significant attention recently. It is important to recognize that multi-user online positioning occurs in real wireless environments.

Visual cues of soft-tissue behaviour in minimal-invasive and robotic surgery.

Minimal-invasive surgery (MIS) and robotic surgery (RS) offer multiple advantages over open surgery (Vajsbaher et al. in Cogn Syst Res 64:08, 2020). However, the lack of haptic feedback is still a limitation.

Characterization and Performance Evaluation of Magnesium Chloride-Enriched Polyurethane Nanofiber Patches for Wound Dressings.

Purpose: Wound patches are essential for wound healing, yet developing patches with enhanced mechanical and biological properties remains challenging. This study aimed to enhance the mechanical and biological properties of polyurethane (PU) by incorporating magnesium chloride (MgCl) into the patch.

Methodology: The composite patch was fabricated using the electrospinning technique, producing nanofibers from a mixture of PU and MgCl solutions.

A critical review on the charging and transport dynamics of atmospheric radioactive aerosols: Fundamentals and advances.

Upon the release of natural or anthropogenic radionuclides into the atmosphere, dispersion models are relied on to predict their spread range and fallout field. The accurate prediction of the transport and deposition of atmospheric radioactive aerosols involves several highly coupled, multi-physical processes. This work systematically covers the physical principles governing the transport dynamics, deposition rates, charge evolution, radioactive decay, and coagulation mechanisms of atmospheric radioactive aerosols, particularly in hot, arid climates and during dust outbreaks.

Direct C-H functionalisation of azoles Minisci reactions.

Azoles have widespread applications in medicinal chemistry; for example, thiazoles, imidazoles, benzimidazoles, isoxazoles, tetrazoles and triazoles appear in the top 25 most frequently used N-heterocycles in FDA-approved drugs. Efficient routes for the late-stage C-H functionalisation of azole cores would therefore be highly desirable. The Minisci reaction, a nucleophilic radical addition reaction onto N-heterocyclic bases, is a direct C-H functionalisation reaction that has the potential to be a powerful method for C-H functionalisations of azole scaffolds.

Epigenetic memory of radiotherapy in dermal fibroblasts impairs wound repair capacity in cancer survivors.

Radiotherapy (RT), a common cancer treatment, unintentionally harms surrounding tissues, including the skin, and hinders wound healing years after treatment. This study aims to understand the mechanisms behind these late-onset adverse effects. We compare skin biopsies from previously irradiated (RT) and non-irradiated (RT) sites in breast cancer survivors who underwent RT years ago.

Modeling traffic pollutants in a street canyon by CFD: Idealized line sources versus multiple realistic car sources.

Idealized sources are commonly used to reproduce the traffic emission in street canyons in experimental and numerical investigations. However, it remains unclear whether idealized sources can accurately reproduce the pollutant dispersion compared to more realistic sources. The goal of this paper is to investigate the impact of idealized and realistic sources on traffic-induced pollutant concentration in a street canyon by numerical simulation with Computational Fluid Dynamics (CFD).

Path Tracing-Inspired Modeling of Non-Line-of-Sight SPAD Data.

Non-Line of Sight (NLOS) imaging has gained attention for its ability to detect and reconstruct objects beyond the direct line of sight, using scattered light, with applications in surveillance and autonomous navigation. This paper presents a versatile framework for modeling the temporal distribution of photon detections in direct Time of Flight (dToF) Lidar NLOS systems. Our approach accurately accounts for key factors such as material reflectivity, object distance, and occlusion by utilizing a proof-of-principle simulation realized with the Unreal Engine.

A molecular dynamics simulation study of EthylChlorophyllide A molecules confined in a SiO2 nanoslit.

This paper investigates the dynamic behavior of EthylChlorophyllide A (EChlideA) molecules in a methanol solution confined within a 4 nm silica nanoslit, using molecular dynamics simulations over a duration of 1 ms. Three systems, containing 1, 2, and 4 solutes, were studied at 298 K. The results demonstrate that EChlideA molecules predominantly adsorb onto the silica surfaces, driven by specific interactions between chlorin ring's methyl group and the hydroxyl groups of the silica.

Towards an improved wind effect assessment for asbestos abatement: A methodology for reduced-scale experiments.

During building renovation or demolition, asbestos fibers can be released which can contaminate the environment, leading to potential occupational health and public health concerns. Strict asbestos abatement procedures and regulations are in place to mitigate this risk, which involve sealing the worksite and depressurizing it relative to the outdoor environment (i.e.

A compound analysis of medical device clinical trials registered in Africa on clinicaltrials.gov.

Background: Africa, specifically the Sub-Saharan region, has had numerous medical technology clinical trials to address the various healthcare challenges around infectious diseases, non-communicable diseases, and nutritional disorders it is facing. Medical device clinical trials provide performance data in terms of safety, efficacy, and efficiency, which is a requirement before commercialization. Key players such as academicians, governments, international organizations, and funders collaborate to drive these trials, but their growth in Africa remains slower compared to other parts of the globe.

Manganese 2-phosphinophosphinine precatalysts for methanol/ethanol upgrading to isobutanol.

Two Mn-phosphinophosphinine complexes were synthesised from reaction of the proligand with [MnBr(CO)] at 80 °C for 2 h; 2-diphenylphosphino-3-methyl-6-trimethylsilylphosphinine manganese tricarbonyl bromide (2TMS) and 2-diphenylphosphino-3-methyl-phosphinine manganese tricarbonyl bromide (2H). P{H} NMR spectroscopy revealed characteristic chemical shifts for the phosphinine and phosphine donors bound to Mn (255.4 and 23.