217 results match your criteria: "School of Engineering and Informatics[Affiliation]"

Temperature effects on gallium arsenide Ni betavoltaic cell.

Appl Radiat Isot

July 2017

Semiconductor Materials and Devices Laboratory, School of Engineering and Informatics, University of Sussex, Brighton BN1 9QT, UK.

A GaAs Ni radioisotope betavoltaic cell is reported over the temperature range 70°C to -20°C. The temperature effects on the key cell parameters were investigated. The saturation current decreased with decreased temperature; whilst the open circuit voltage, the short circuit current, the maximum power and the internal conversion efficiency values decreased with increased temperature.

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Metamaterial bricks and quantization of meta-surfaces.

Nat Commun

February 2017

INTERACT Lab, School of Engineering and Informatics, University of Sussex, Brighton BN1 9RH, UK.

Controlling acoustic fields is crucial in diverse applications such as loudspeaker design, ultrasound imaging and therapy or acoustic particle manipulation. The current approaches use fixed lenses or expensive phased arrays. Here, using a process of analogue-to-digital conversion and wavelet decomposition, we develop the notion of quantal meta-surfaces.

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Applications and Engineering Analysis of Lotus Roots under External Water Pressure.

Appl Bionics Biomech

December 2016

School of Engineering and Informatics, University of Sussex, Brighton BN1 9QJ, UK.

Engineers can learn from nature for inspirations to create new designs. The internal structure of lotus roots with several oval holes was studied in this paper for engineering inspirations. The structural performance of lotus roots under outside water pressure was simulated and compared with various cross-sectional areas.

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Global and local complexity of intracranial EEG decreases during NREM sleep.

Neurosci Conscious

January 2017

Sackler Centre for Consciousness Science and School of Engineering and Informatics, University of Sussex, Brighton, UK.

Key to understanding the neuronal basis of consciousness is the characterization of the neural signatures of changes in level of consciousness during sleep. Here we analysed three measures of dynamical complexity on spontaneous depth electrode recordings from 10 epilepsy patients during wakeful rest (WR) and different stages of sleep: (i) Lempel-Ziv complexity, which is derived from how compressible the data are; (ii) amplitude coalition entropy, which measures the variability over time of the set of channels active above a threshold; (iii) synchrony coalition entropy, which measures the variability over time of the set of synchronous channels. When computed across sets of channels that are broadly distributed across multiple brain regions, all three measures decreased substantially in all participants during early-night non-rapid eye movement (NREM) sleep.

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Active interoceptive inference and the emotional brain.

Philos Trans R Soc Lond B Biol Sci

November 2016

Wellcome Trust Centre for Neuroimaging, Institute of Neurology, UCL, London WC1N 3BG, UK.

We review a recent shift in conceptions of interoception and its relationship to hierarchical inference in the brain. The notion of interoceptive inference means that bodily states are regulated by autonomic reflexes that are enslaved by descending predictions from deep generative models of our internal and external milieu. This re-conceptualization illuminates several issues in cognitive and clinical neuroscience with implications for experiences of selfhood and emotion.

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The Uniformity Illusion.

Psychol Sci

January 2017

2 Sackler Centre for Consciousness Science, University of Sussex.

Vision in the fovea, the center of the visual field, is much more accurate and detailed than vision in the periphery. This is not in line with the rich phenomenology of peripheral vision. Here, we investigated a visual illusion that shows that detailed peripheral visual experience is partially based on a reconstruction of reality.

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The mechanisms of variation, selection and inheritance, on which evolution by natural selection depends, are not fixed over evolutionary time. Current evolutionary biology is increasingly focussed on understanding how the evolution of developmental organisations modifies the distribution of phenotypic variation, the evolution of ecological relationships modifies the selective environment, and the evolution of reproductive relationships modifies the heritability of the evolutionary unit. The major transitions in evolution, in particular, involve radical changes in developmental, ecological and reproductive organisations that instantiate variation, selection and inheritance at a higher level of biological organisation.

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AlGaAs Fe X-ray radioisotope microbattery.

Sci Rep

December 2016

Semiconductor Materials and Device Laboratory, School of Engineering and Informatics, University of Sussex, Brighton, BN1 9QT, UK.

This paper describes the performance of a fabricated prototype AlGaAs Fe radioisotope microbattery photovoltaic cells over the temperature range -20 °C to 50 °C. Two 400 μm diameter p-i-n (3 μm i-layer) AlGaAs mesa photodiodes were used as conversion devices in a novel X-ray microbattery prototype. The changes of the key microbattery parameters were analysed in response to temperature: the open circuit voltage, the maximum output power and the internal conversion efficiency decreased when the temperature was increased.

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This paper outlines a hierarchical Bayesian framework for interoception, homeostatic/allostatic control, and meta-cognition that connects fatigue and depression to the experience of chronic dyshomeostasis. Specifically, viewing interoception as the inversion of a generative model of viscerosensory inputs allows for a formal definition of dyshomeostasis (as chronically enhanced surprise about bodily signals, or, equivalently, low evidence for the brain's model of bodily states) and allostasis (as a change in prior beliefs or predictions which define setpoints for homeostatic reflex arcs). Critically, we propose that the performance of interoceptive-allostatic circuitry is monitored by a metacognitive layer that updates beliefs about the brain's capacity to successfully regulate bodily states (allostatic self-efficacy).

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Detectability of Granger causality for subsampled continuous-time neurophysiological processes.

J Neurosci Methods

January 2017

Sackler Centre for Consciousness Science and School of Engineering and Informatics, University of Sussex, Brighton BN1 9QJ, UK. Electronic address:

Background: Granger causality is well established within the neurosciences for inference of directed functional connectivity from neurophysiological data. These data usually consist of time series which subsample a continuous-time biophysiological process. While it is well known that subsampling can lead to imputation of spurious causal connections where none exist, less is known about the effects of subsampling on the ability to reliably detect causal connections which do exist.

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Olfactory experience shapes the evaluation of odour similarity in ants: a behavioural and computational analysis.

Proc Biol Sci

August 2016

Centre National de la Recherche Scientifique (CNRS), Research Centre on Animal Cognition (UMR5169), Toulouse, France Research Centre on Animal Cognition (UMR5169), University Paul-Sabatier, Toulouse, France

Perceptual similarity between stimuli is often assessed via generalization, the response to stimuli that are similar to the one which was previously conditioned. Although conditioning procedures are variable, studies on how this variation may affect perceptual similarity remain scarce. Here, we use a combination of behavioural and computational analyses to investigate the influence of olfactory conditioning procedures on odour generalization in ants.

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Three-Dimensional Digital Template Atlas of the Macaque Brain.

Cereb Cortex

September 2017

Laboratory of Neuropsychology, National Institute of Mental Health, National Institute of Health (NIMH/NIH), MD 20892, USA.

We present a new 3D template atlas of the anatomical subdivisions of the macaque brain, which is based on and aligned to the magnetic resonance imaging (MRI) data set and histological sections of the Saleem and Logothetis atlas. We describe the creation and validation of the atlas that, when registered with macaque structural or functional MRI scans, provides a straightforward means to estimate the boundaries between architectonic areas, either in a 3D volume with different planes of sections, or on an inflated brain surface (cortical flat map). As such, this new template atlas is intended for use as a reference standard for macaque brain research.

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25th Annual Computational Neuroscience Meeting: CNS-2016.

BMC Neurosci

August 2016

Institut de Neuroscienes de la Timone (INT), CNRS & Aix-Marseille University, 27 Boulevard Jean Moulin, 13005 Marseille, France

Article Synopsis
  • The text includes a collection of research topics related to neural circuits, mental disorders, and computational models in neuroscience.
  • It features various studies examining the functional advantages of neural heterogeneity, propagation waves in the visual cortex, and dendritic mechanisms crucial for precise neuronal functioning.
  • The research covers a range of applications, from understanding complex brain rhythms to modeling auditory processing and investigating the effects of neural regulation on behavior.
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X-ray detection with zinc-blende (cubic) GaN Schottky diodes.

Sci Rep

July 2016

Semiconductor Materials and Devices Laboratory, School of Engineering and Informatics, University of Sussex, Falmer, Brighton BN1 9QT, UK.

The room temperature X-ray responses as functions of time of two n type cubic GaN Schottky diodes (200 μm and 400 μm diameters) are reported. The current densities as functions of time for both diodes showed fast turn-on transients and increases in current density when illuminated with X-ray photons of energy up to 35 keV. The diodes were also electrically characterized: capacitance, implied depletion width and dark current measurements as functions of applied bias at room temperature are presented.

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Maximizing the spatial representativeness of NO2 monitoring data using a combination of local wind-based sectoral division and seasonal and diurnal correction factors.

J Environ Sci Health A Tox Hazard Subst Environ Eng

October 2016

c Department of Civil , Structural and Environmental Engineering, Museum Building, Trinity College Dublin, Dublin , Ireland.

This article describes a new methodology for increasing the spatial representativeness of individual monitoring sites. Air pollution levels at a given point are influenced by emission sources in the immediate vicinity. Since emission sources are rarely uniformly distributed around a site, concentration levels will inevitably be most affected by the sources in the prevailing upwind direction.

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Burst Firing Enhances Neural Output Correlation.

Front Comput Neurosci

May 2016

Centre for Computational Neuroscience and Robotics, School of Engineering and Informatics, University of Sussex Brighton, UK.

Neurons communicate and transmit information predominantly through spikes. Given that experimentally observed neural spike trains in a variety of brain areas can be highly correlated, it is important to investigate how neurons process correlated inputs. Most previous work in this area studied the problem of correlation transfer analytically by making significant simplifications on neural dynamics.

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In many application domains, conventional e-noses are frequently outperformed in both speed and accuracy by their biological counterparts. Exploring potential bio-inspired improvements, we note a number of neuronal network models have demonstrated some success in classifying static datasets by abstracting the insect olfactory system. However, these designs remain largely unproven in practical settings, where sensor data is real-time, continuous, potentially noisy, lacks a precise onset signal and accurate classification requires the inclusion of temporal aspects into the feature set.

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This paper introduces an integer order approximation method for numerical implementation of fractional order derivative/integrator operators in control systems. The proposed method is based on fitting the stability boundary locus (SBL) of fractional order derivative/integrator operators and SBL of integer order transfer functions. SBL defines a boundary in the parametric design plane of controller, which separates stable and unstable regions of a feedback control system and SBL analysis is mainly employed to graphically indicate the choice of controller parameters which result in stable operation of the feedback systems.

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Neuromorphic computing employs models of neuronal circuits to solve computing problems. Neuromorphic hardware systems are now becoming more widely available and "neuromorphic algorithms" are being developed. As they are maturing toward deployment in general research environments, it becomes important to assess and compare them in the context of the applications they are meant to solve.

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GPU acceleration of time-domain fluorescence lifetime imaging.

J Biomed Opt

January 2016

University of Strathclyde, Strathclyde Institute of Pharmacy and Biomedical Sciences, Centre for Biophotonics, Glasgow G4 ORE, United KingdombUniversity of Sussex, School of Engineering and Informatics, Brighton BN1 9QJ, United Kingdom.

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GeNN: a code generation framework for accelerated brain simulations.

Sci Rep

January 2016

Centre for Computational Neuroscience and Robotics, School of Engineering and Informatics, University of Sussex, Brighton, BN1 9QJ, UK.

Large-scale numerical simulations of detailed brain circuit models are important for identifying hypotheses on brain functions and testing their consistency and plausibility. An ongoing challenge for simulating realistic models is, however, computational speed. In this paper, we present the GeNN (GPU-enhanced Neuronal Networks) framework, which aims to facilitate the use of graphics accelerators for computational models of large-scale neuronal networks to address this challenge.

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Wearable electronics are gaining widespread use as enabling technologies, monitoring human physical activity and behavior as part of connected health infrastructures. Attention to human factors and comfort of these devices can greatly positively influence user experience, with a subsequently higher likelihood of user acceptance and lower levels of device rejection. Here, we employ a human factors and comfort assessment methodology grounded in the principles of human-centered design to influence and enhance the design of an instrumented insole.

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Plasma technology has been widely used to increase the surface energy of the polymer surfaces for many industrial applications; in particular to increase in wettability. The present work was carried out to investigate how surface modification using plasma treatment modifies the surface energy of micro-injection moulded microneedles and its influence on drug delivery. Microneedles of polyether ether ketone and polycarbonate and have been manufactured using micro-injection moulding and samples from each production batch have been subsequently subjected to a range of plasma treatment.

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