A retrospective 'target trial emulation' comparing amiodarone and lidocaine for adult out-of-hospital cardiac arrest resuscitation.

Objective: The administration of amiodarone or lidocaine is recommended during the resuscitation of out-of-hospital cardiac arrest (OHCA) patients presenting with defibrillation-refractory or recurrent ventricular fibrillation or ventricular tachycardia. Our objective was to use 'target trial emulation' methodology to compare the outcomes of patients who received amiodarone or lidocaine during resuscitation.

Methods: Adult, non-traumatic OHCA patients in the ESO Data Collaborative 2018-2023 datasets who experienced OHCA prior to EMS arrival, presented with a shockable rhythm, and received amiodarone or lidocaine during resuscitation were evaluated for inclusion.

A mixed method evaluation of a novel targeted health messaging intervention to promote COVID-19 protective behaviours and vaccination among Black and South Asian communities living in the UK (The COBHAM study).

Aim: To evaluate an intervention (a film and electronic leaflet) disseminated via text message by general practices to promote COVID-19 preventative behaviours in Black and South Asian communities.

Methods: We carried out a before-and-after questionnaire study of attitudes to and implementation of COVID-19 preventative behaviours and qualitative interviews about the intervention with people registered with 26 general practices in England who identified as Black or South Asian.

Results: In the 108 people who completed both questionnaires, we found no significant change in attitudes to and implementation of COVID-19 preventative behaviours, although power was too low to detect significant effects.

Bayesian Borrowing With Multiple Heterogeneous Historical Studies Using Order Restricted Normalized Power Prior.

The recent U.S. Food and Drug Administration guidance on complex innovative trial designs acknowledges the use of Bayesian strategies to incorporate historical information based on clinical expertise and data similarity.

Molecular Characterization, Recombinant Expression, and Functional Analysis of Carboxypeptidase B in .

The Pacific white shrimp () is economically significant, and its growth is regulated by multiple factors. Carboxypeptidase B (CPB) is related to protein digestion, but its gene sequence and features in are not fully understood. This study aimed to explore the molecular and functional properties of CPB in .

Likes, Shares, and Symptoms: The Hidden Toll of Early Adolescents' Social Media Use on Well-Being.

Social media use has rapidly increased over the past decade, especially among young people. To obtain more insight into the potential negative associations with problematic social media use in Dutch early adolescents, we assessed its relation to self-reported well-being. We conducted a cross-sectional study with 585 students in their final year of primary school (11-12 years old) who completed a questionnaire during school hours.

The Effects of the Mamanet Cachibol League Intervention Program on Perceived Health Status, Mental Health, and Healthy Lifestyle Among Arab Women.

The Israeli Mamanet Cachibol League (MCL) is a community-oriented athletic program serving mothers through non-competitive recreational sports participation. This study aimed to assess the effects of the MCL on perceived health status, mental health (happiness, depression, social capital), and healthy lifestyle behaviors (physical activity and nutrition). This is an experimental study with a sample of 231 women (174 in the experimental group and 57 in the control).

Sedentary Behaviour and Its Correlates Among Older Adults in Malaysia.

Sedentary behaviors (SBs), which are low-energy, wakeful activities performed in a sitting, reclining, or lying posture, are independently associated with numerous adverse health outcomes, including mental health disorders, non-communicable diseases, and an increased risk of mortality. This study investigated associations between sociodemographic characteristics, lifestyle factors, mental health, nutritional status, social support, functional limitations, and SB among older persons in Malaysia. Data from 3977 individuals aged 60 years and above, extracted from the National Health and Morbidity Survey (NHMS) 2018, were analyzed using complex samples logistic regression.

Exploring the relationship between physical activity and Inhibitory Function in College Students with depressive symptoms through EEG.

This study aims to examine the relationship between physical activity and inhibitory function in college students with depressive symptoms and to explore the role of resting EEG as a mediator in this relationship. Specifically, it analyzes how physical activity correlates with inhibitory function and identifies potential routes through which physical activity impacts inhibitory function. A cross-sectional study was conducted involving 154 college students with depressive symptoms.

The association between initial defibrillation dose and outcomes following adult out-of-hospital cardiac arrest resuscitation: a retrospective, multi-agency study.

Introduction: Effective defibrillation is essential to out-of-hospital cardiac arrest (OHCA) survival. International guidelines recommend initial defibrillation energies between 120 and 360 Joules, which has led to widespread practice variation. Leveraging this natural experiment, we aimed to explore the association between initial defibrillation dose and outcome following OHCA.

The intelligent brain and the energy heart: Synergistic evolution of artificial intelligence and energy storage technology in China.

In the context of China's ongoing industrial revolution and technological transformation, there is a growing demand for advanced energy management solutions and the increasing role of artificial intelligence in various industries. This paper aims to explore how artificial intelligence (AI) and Energy Storage Technology (EST) interact and co-evolve. Utilizing a full-sample Granger causality test, we identified significant interactions between AI and EST.

The impact of climate change on Korea's agricultural sector under the national self-sufficiency policy.

Evolving environmental conditions due to climate change have brought about changes in agriculture, which is required for human life as both a source of food and income. International trade can act as a buffer against potential negative impacts of climate change on crop yields, but recent years have seen breakdowns in global trade, including export bans to improve domestic food security. For countries that rely heavily on imported food, governments may institute policies to protect their agricultural industry from changes in climate-induced crop yield changes and other countries' potential trade restrictions.

Measuring trade costs and analyzing the determinants of trade growth between Cambodia and major trading partners: 1993-2019.

High trade costs pose substantial barriers to the process of trade liberalization. This study aims to measure trade costs and explore the driving forces behind the growth of bilateral trade between Cambodia and its top 30 trading partners from 1993 to 2019. Using a micro-founded measure of trade costs derived from the gravity model, we find that Cambodia's average trade costs decreased by 35.

Do CEOs with government work experience foster enterprise investment in pollution control?

As enterprise leaders, CEOs play a critical role in driving enterprise investment in pollution control. However, few studies have explored the motivations behind enterprise investment in pollution control, primarily how CEOs' early experiences influence their decisions. Based on the perspective of imprinting theory, this study examines the impact of CEOs with government work experience on enterprise investment in pollution control and the boundary conditions of this impact.

Exploring entrepreneurial intention among European Union youth by education and employment status.

The relatively high vulnerability of young Europeans in the labour market compared to other age groups has led many to seek alternative employment solutions, such as entrepreneurship. While not a comprehensive solution, entrepreneurial initiatives among youth can offer a valuable opportunity for their integration into stable and decent work. This research uses Flash Eurobarometer 513-Social Entrepreneurship and Youth to explore entrepreneurial intentions among European Union youth.

Long-term wage inequality in imperial China: From 202 BCE to 1912 CE.

This paper attempts to describe and explain the long-term evolution of wage inequality in imperial China, covering over two millennia from the Han dynasty to the Qing dynasty (202 BCE-1912 CE). Based on historical government records of official salaries, commodity prices, and agricultural productivity, we convert various forms of salaries to equivalent rice volumes and comparable salary benchmarks. Wage inequality is measured by salary ratios and (partial) Gini coefficients between official and peasant classes as well as within the official class.

Exploring volatility transmission in Capesize freight contracts: Insights from energy and commodity markets.

Analyzing the interactions between spot and time charter freight is crucial for the maritime industry. While numerous studies have explored the relationship between average freight indices and spillover effects, a gap remains in understanding the deeper connections between inter-regional shipping routes and chartering contracts. This research investigates the role of Capesize freight dynamics in shaping the regional dry bulk freight market, with a focus on the influence of energy and commodity price fluctuations.

Improved daily PM estimates in India reveal inequalities in recent enhancement of air quality.

Poor ambient air quality poses a substantial global health threat. However, accurate measurement remains challenging, particularly in countries such as India where ground monitors are scarce despite high expected exposure and health burdens. This lack of precise measurements impedes understanding of changes in pollution exposure over time and across populations.

Generative adversarial local density-based unsupervised anomaly detection.

Anomaly detection is crucial in areas such as financial fraud identification, cybersecurity defense, and health monitoring, as it directly affects the accuracy and security of decision-making. Existing generative adversarial nets (GANs)-based anomaly detection methods overlook the importance of local density, limiting their effectiveness in detecting anomaly objects in complex data distributions. To address this challenge, we introduce a generative adversarial local density-based anomaly detection (GALD) method, which combines the data distribution modeling capabilities of GANs with local synthetic density analysis.

Impact of mergers and acquisitions on firms' performance adjusted to business cycle fluctuations in China.

This research mainly explored the effects of mergers and acquisitions (M&As) on the financial performance of Chinese listed companies and the determinants of post-M&A financial performance of mergers by incorporating adjustments for business cycle fluctuations. The research was divided into two parts. The first part applied data envelopment analysis (DEA) models for the calculation of the financial performance scores of mergers and non-mergers in six major sectors before and after M&As.

Low-cost and scalable machine learning model for identifying children and adolescents with poor oral health using survey data: An empirical study in Portugal.

This empirical study assessed the potential of developing a machine-learning model to identify children and adolescents with poor oral health using only self-reported survey data. Such a model could enable scalable and cost-effective screening and targeted interventions, optimizing limited resources to improve oral health outcomes. To train and test the model, we used data from 2,133 students attending schools in a Portuguese municipality.

Variations in land surface temperature increase in South-East Asian Cities.

Climate change and global warming are terms used to describe the variation in the Earth's mean temperature as a result of human activities contributing to the formation of urban heat islands (UHI). One method for determining the temperature of a region is the land surface temperature (LST). The study of LSTs is important and closely related to climate change, as is the provision of convenient living and working conditions in cities, which support economic growth.

Hybrid Quality-Based Recommender Systems: A Systematic Literature Review.

As technology develops, consumer behavior and how people search for what they want are constantly evolving. Online shopping has fundamentally changed the e-commerce industry. Although there are more products available than ever before, only a small portion of them are noticed; as a result, a few items gain disproportionate attention.

Impact of Ethical Leadership on Autonomy and Self-Efficacy in Virtual Work Environments: The Disintegrating Effect of an Egoistic Climate.

Ethical management is key to ensuring organizational sustainability, through resources such as autonomy or self-efficacy. However, economic and social uncertainty occasionally leads to adaptive responses that prioritize profit as the primary interest, blurring the integrating role of ethical leadership. There are a number of studies that support this reality in a virtual work environment.

The Particularities of Employees' Green Ethical Behavior in the Oil and Gas Sector.

The article aims to evaluate the particularities of the green, ethical behavior of employees from the oil and gas sector in light of climate change and sustainable development. We employed a quantitative research approach and partial least squares structural equation modeling (PLS-SEM) using SmartPLS4 software (version 4.1.

Environmental Performance, Financial Constraints, and Tax Avoidance Practices: Insights from FTSE All-Share Companies.

Through its initiative known as the Climate Change Act (2008), the Government of the United Kingdom encourages corporations to enhance their environmental performance with the significant aim of reducing targeted greenhouse gas emissions by the year 2050. Previous research has predominantly assessed this encouragement favourably, suggesting that improved environmental performance bolsters governmental efforts to protect the environment and fosters commendable corporate governance practices among companies. Studies indicate that organisations exhibiting strong corporate social responsibility (CSR), environmental, social, and governance (ESG) criteria, or high levels of environmental performance often engage in lower occurrences of tax avoidance.