5 results match your criteria: "School of Dentistry-University of North Carolina at Chapel Hill[Affiliation]"

Geroscience: Aging and Oral Health Research.

Adv Dent Res

November 2023

Biosystems and Function and Periodontics, School of Dentistry, University of California, Los Angeles, Los Angeles, CA, USA.

Research in aging has significantly advanced; scientists are now able to identify interventions that slow the biologic aging processes (i.e., the "hallmarks of aging"), thus delaying the onset and progression of multiple diseases, including oral conditions.

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Oral candidiasis (OC) is the most prevalent HIV-related oral lesion in patients on combined anti-retroviral therapy (cART) or without cART. Management is challenged in some patients by development of resistance to azole drugs, such as fluconazole. Recent scientific knowledge about OC pathogenesis, the role of OC in the immune reconstitution inflammatory syndrome (IRIS), the relationship of OC with the microbiome, and novelties in OC treatment was discussed in an international workshop format.

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Purpose: To compare the repair potential of a packable composite (Filtek P60) to that of a conventional hybrid composite (Pertac II) using three different adhesives: an unfilled resin (EBS-Multi), a one-bottle, acetone-based adhesive (One-Step), and a self-etching adhesive (Prompt L-Pop).

Materials And Methods: 30 composite disks (diameter = 8 mm) of each composite material were fabricated, light-cured, and stored in 37 degrees C for 7 days. The specimens were polished to 600-grit, sandblasted (CoJet-System), silanated, and randomly assigned to three groups (n=10).

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Despite extensive investigation, the development mechanism or mechanisms resulting in dental fluorosis are unknown. Several hypotheses suggest abnormal matrix synthesis, secretion, and delayed and/or defective matrix degradation with retention of enamel protein. The purpose of this study was to characterize the protein composition of fluorosed human enamel.

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