311,838 results match your criteria: "School of Dentistry; Private Practice[Affiliation]"

Background/purpose: The impact of thermal behavior on the clinical performance of gutta-percha points (GP) is unclear. This study aimed to investigate the thermal behavior of three different types of GP and their temperature changes (TC) in a simulated clinical environment.

Materials And Methods: The GP tested were Conform Fit® Gutta-Percha Points (CF), Autofit™ Feathered Tip Gutta Percha (AF), and Gutta Percha Root Canal Points (GC).

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Background/purpose: Revascularization procedures are used over apexification to treat teeth with necrotic pulp tissues and incomplete root formation. Clinically, inducing proliferation, migration, matrix deposition, and differentiation of stem cells from apical papilla (SCAPs) are critical for pulp regeneration. The study aimed to elucidate the impact of bone morphogenetic protein-4 (BMP-4) on plasminogen activation molecules and the osteogenic/odontogenic differentiation of SCAPs, as well as understand the related signaling mechanisms.

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Background/purpose: Dental implants can restore both function and aesthetics in edentulous areas. However, the absence of cushioning mechanical behavior in implants may limit their clinical performance and reduce the long-term survival rates. This study aimed to establish an implant cushion mechanism that mimicked the natural periodontal ligament, utilizing the properties of composite hydrogels.

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Biomineralization reaction from nanosized calcium silicate: A new method for reducing dentin hypersensitivity.

J Dent Sci

January 2025

Department of Conservative Dentistry, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, Republic of Korea.

Background/purpose: This study assessed the ability of experimental materials consisting of dicalcium silicate (DCS) and tricalcium silicate (TCS) with nanosized particles to form intratubular crystals under phosphate-buffered saline (PBS) and the effect on dentin permeability reduction.

Materials And Methods: By isolating the cervical part of the extracted premolars, 195 specimens were obtained. Two experimental materials (DCS/TCS and TCS) were applied to the dentin surface by brushing and stored in PBS (n = 65).

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Background/purpose: COVID-19 vaccines are supplied at no-cost to residents as a measure to prevent comorbidities, fatalities, and the increased risk of community transmission, thus protecting public health systems. However, vaccine acceptance among cancer patients remained uncertain. This study aimed to elucidate the vaccination rates among oral cancer patients at a medical center in Taiwan.

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Background/purpose: Salivary microbiome has become a surrogate indicator of oral disease due to its collective reservoirs and convenience in sampling. However, failed clinical trials often lead to wastes of resources, indicating a need for preclinical models. In this pilot study, we aimed to compare the salivary microbiome by metagenomics analysis before and after lysogeny broth culture for prospective translational studies.

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Background/purpose: The relationship among chewing ability, food texture selection, and nutritional status in the elderly is well-known. This study tried to find the reliable biomarkers to predict the chewing ability and nutritional status of the elderly people.

Materials And Methods: Sixty-eight elderly subjects (mean age, 80.

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Background/purpose: Complications, such as postoperative pneumonia, can occur after pediatric cardiac surgery; however, studies on related changes in perioperative oral bacterial counts are scarce. Herein, we investigated the changes in oral bacterial counts before and after surgery in infants who underwent cardiac surgery, as well as after oral care using an antiseptic mouthwash.

Materials And Methods: A total of 102 infants who underwent congenital heart disease surgery were enrolled in this study.

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Background/purpose: Dentists often focus on masticatory performance (MP) rather than masticatory ability (MA) and treatment expectations when evaluating older adults. This study aimed to determine if MA aligns with MP and to explore influencing factors.

Materials And Methods: This cross-sectional study utilized a multi-stage stratified cluster sampling, including one thousand community-dwelling adults aged 60 and older.

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Background/purpose: Oral mucosal lesions are associated with a variety of pathological conditions. Most deep-learning-based convolutional neural network (CNN) systems for computer-aided diagnosis of oral lesions have typically concentrated on determining limited aspects of differential diagnosis. This study aimed to develop a CNN-based diagnostic model capable of classifying clinical photographs of oral ulcerative and associated lesions into five different diagnoses, thereby assisting clinicians in making accurate differential diagnoses.

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Background/purpose: Dental management prior to radiotherapy is often time-critical, and there are no studies on whether manipulations such as tooth extraction influence the risk of severe radiation-induced oral mucositis (ROM) during radiotherapy. Therefore, the aim of this study was to describe the relationship between dental management and the incidence of severe ROM.

Materials And Methods: A retrospective analysis was conducted on 144 head and neck cancer (HNC) patients who received dental management before radiotherapy at Peking University Cancer Hospital, from January 2016 to December 2017.

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Background/purpose: Artificial intelligence (AI) can assist in medical diagnosis owing to its high accuracy and efficiency. This study aimed to develop a diagnostic system for automatically determining the degree of tooth wear (TW) using intraoral photographs with deep learning.

Materials And Methods: The study included 388 intraoral photographs.

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Background/purpose: Although clinical studies have suggested a link between non-axial forces and reduced longevity of cervical restorations, the underlying mechanisms require further numerical investigation. This in-silico study employed a cohesive zone model (CZM) to investigate interfacial damage in a cervical restoration subjected to different load directions.

Materials And Methods: A plane strain model of a maxillary premolar was established, with a wedge-shaped buccal cervical restoration.

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Background/purpose: In general, improving oral health can reduce the risk of pneumonia. The purpose of this retrospective cohort study was to investigate the risk of pneumonia between cerebral palsy (CP) cohort and non-CP cohort as well as the association of pneumonia with the number of dental visits in CP patients in Taiwan.

Materials And Methods: We identified 10,544 patients who were diagnosed with CP between 2010 and 2019 from the Taiwan National Health Insurance Research Database.

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Background/purpose: -2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside (THSG) is a bioactive component in the Chinese herb Polygonum multiflorum, recognized for its anti-inflammatory and lipid-lowering properties. Human dental pulp stem cells (hDPSCs) have excellent capabilities in tooth regeneration, wound healing, and neural repair. The exosomes (Exo) released by hDPSCs contain bioactive molecules that influence cell proliferation, differentiation, and immune responses.

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Loss of dental pulp potentially increased the risk of Alzheimer's dementia.

J Dent Sci

January 2025

Department of Oral Physiology, School of Dentistry, Seoul National University, Seoul, Republic of Korea.

Background/purpose: Chronic periodontitis and tooth loss contribute to cognitive decline. Since many biological processes are shared by loss of teeth and loss of pulps, this study investigated the potential association between loss of pulp and the development of dementia.

Materials And Methods: A retrospective cohort analysis was conducted to investigate the association between dental treatment and the development of dementia.

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Background: : The metabolic by-product butyric acid of Gram-negative anaerobic bacteria can invoke pathological effects on periodontal cells resulting in inflammation and further destruction of periodontium. However, limited researches on the effects of butyric acid on cementoblasts were reported. Therefore, this study aimed to investigate the type of cell death in murine cementoblast (OCCM.

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Background/purpose: The performance of intraoral scanners (IOSs) relies on the operator's skills. However, whether operator experience influences IOS accuracy remains unclear. This study investigated the effect of operator experience on the trueness accuracy and time-based efficiency of IOSs.

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Background/purpose: studies are essential for understanding cellular responses, but traditional culture systems often neglect the three-dimensional (3D) structure of real implants, leading to limitations in cellular recruitment and behavior largely governed by gravity. The objective of this study was to pioneer a novel 3D dynamic osteoblastic culture system for assessing the biological capabilities of dental implants in a more clinically and physiologically relevant manner.

Materials And Methods: Rat bone marrow-derived osteoblasts were cultured in a 24-well dish with a vertically positioned dental implant.

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Background/purpose: Inferior alveolar nerve (IAN) injury is the most serious complication associated with dental implant surgery, posing difficulties in treatment and potential for permanent disabilities. This study aimed to identify patient-related risk factors for IAN injury during implant placement and to investigate sensory disturbances depending on whether the implant was removed.

Materials And Methods: Twenty-eight patients with implant-related IAN injury were included.

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Background/purpose: OpenAI's GPT-4V and Google's Gemini Pro, being Large Language Models (LLMs) equipped with image recognition capabilities, have the potential to be utilized in future medical diagnosis and treatment, ands serve as valuable educational support tools for students. This study compared and evaluated the image recognition capabilities of GPT-4V and Gemini Pro using questions from the Japanese National Dental Examination (JNDE) to investigate their potential as educational support tools.

Materials And Methods: We analyzed 160 questions from the 116th JNDE, administered in March 2023, using ChatGPT-4V, and Gemini Pro, which have image recognition functions.

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