Fracture resistance of analog and CAD-CAM long-span fixed provisional restorations: An in vitro experimental study.

Purpose: This study aimed to evaluate and compare the fracture resistance of long-span fixed provisional restorations fabricated using milling, three-dimensional (3D) printing, and conventional methods.

Materials And Methods: Sixty specimens were prepared, divided into four groups of 15 each, corresponding to four fabrication methods: computer-aided design and computer-aided manufacturing (CAD-CAM) milled provisional resins, 3D-printed provisional resins, 3D-printed permanent resins, and conventional bis-acryl restorations reinforced with wire. The specimens underwent a three-point bending test using a universal testing machine to measure fracture resistance, quantified as maximum force (in Newtons).

Novel early vertical ridge augmentation technique.

Background/purpose: Multiple augmentation protocols are documented in the literature to rebuild the deficient alveolar ridge after tooth extraction; however, achieving adequate vertical augmentation remains the most challenging goal. This study demonstrated a novel surgical technique of early vertical ridge augmentation for post-dental extraction. This technique offers several biological and technical advantages regarding the timing of the procedure and its relative simplicity compared to other complex techniques.

Improving osteogenic properties of zirconia ceramic via glow discharge plasma-enhanced deposition of amine organic compound.

Background/purpose: Osseointegration potential is greatly depended on the interaction between bone cells and dental implant surface. Since zirconia ceramic has a bioinert surface, functionalization of the surface with an organic compound allylamine was conducted to overcome its drawback of minimal interaction with the surrounding bone.

Materials And Methods: The zirconia surface was initially treated with argon glow discharge plasma (GDP), then combined with amine plasma at three different conditions of 50-W, 75-W and 85-W, to prepare the final samples.

Specialty education and scope of oral and maxillofacial surgery in the United States.

In the United States, Oral and Maxillofacial Surgery (OMS) is a specialty of dentistry that focuses on the management of injuries, diseases, and defects of the head, neck, face, and jaws. The present manuscript is an article on education and training of OMS residents in the United States. It a lso briefly describes the scope of practice of the specialty.

The impact of bleaching using 15% carbamide peroxide on surface properties of CAD-CAM composite structures.

This study aims to evaluate the effects of the home bleaching method on the surface microhardness and surface roughness of both polished and unpolished CAD-CAM resin composite materials. A polymer-infiltrated ceramic network (PICN) block, Enamic (VE), along with four resin composite blocks (RCB) (Grandio [GN], Lava™ Ultimate [LV], BRILLIANT Crios [B], and Cerasmart [CS]), were prepared to dimensions of 14 mm × 12 mm × 2 mm and were categorized into unpolished and polished groups (n = 4). Microhardness measurements were conducted using a Vickers microhardness tester (300 gf load for 20 s) at various time points: before home bleaching, after home bleaching with 15% Opalescence for 8 h and for 56 h, 24 h after bleaching, and one month after bleaching.

Prevalence and risks of sleep bruxism in children and adolescents presenting for orthodontic treatment.

Objectives: This study determined the prevalence and risks of definite sleep bruxism (SB) among children and adolescents presenting for orthodontic treatment.

Methods: This was a cross-sectional study of 7-16-year-old subjects pursuing orthodontic treatment for the first time. The presence or absence of SB was determined using an overnight mandibular movement monitoring inertial measurement sensor, worn by each participant for two consecutive nights.

An introduction to antibacterial materials in composite restorations.

The longevity of direct esthetic restorations is severely compromised because of, among other things, a loss of function that comes from their susceptibility to biofilm-mediated secondary caries, with being the most prevalent associated pathogen. Strategies to combat biofilms range from dental compounds that can disrupt multispecies biofilms in the oral cavity to approaches that specifically target caries-causing bacteria such as . One strategy is to include those antibacterial compounds directly in the material so they can be available long-term in the oral cavity and localized at the margin of the restorations, in which many of the failures initiate.

Successful Management of Palatal Developmental Groove-Associated Periodontal Defect Using Palatal Access Flap and Odontoradiculoplasty: A Case Report.

This case report discusses the successful management of a deep palatal developmental groove associated with Stage III generalized Grade C periodontitis. Despite prior nonsurgical periodontal therapy, the disease progressed rapidly, necessitating further intervention. A comprehensive evaluation revealed generalized periodontitis with localized tooth-related predisposing factor due to a developmental groove in the vital upper left lateral incisor.

A Comparison of the Accuracy of Two Non-dental 3D Printers and a Standard Dental 3D Printer for Printing Dental Models: An In Vitro 3D Analysis.

Background: While the majority of dentists and lab techs recommend dental-specific desktop printers, many of them use cheaper, more affordable 3D printers in their practice. The study aimed to compare the accuracy of two commercial non-dental stereolithography (SLA) 3D printers with a dental 3D printer for diagnostic dental casts.  Methods: A prototype stereolithographic (Standard Triangle/Tessellation Language (STL)) model of a dentoform was used as a master model to be printed by three 3D printers (n=10 for each printer).

Stable Gastric Pentadecapeptide BPC 157 as a Therapy of Severe Electrolyte Disturbances in Rats.

This review explores the therapeutic potential of the stable gastric pentadecapeptide BPC 157 in addressing electrolyte imbalances, specifically hyperkalemia, hypokalemia, hypermagnesemia, and hyperlithemia. In hyperkalemia, BPC 157 demonstrated a comprehensive counteractive effect against KCl overdose (intraperitoneally, intragastrically, and in vitro), effectively mitigating symptoms such as muscular weakness, hypertension, sphincter dysfunction, arrhythmias, and lethality. It also counteracted the adverse effects of succinylcholine and magnesium overdose, including systemic muscle paralysis, arrhythmias, and hyperkalemia.

Minimally Invasive Fixed Prosthodontics: A Narrative Review.

Objective: Minimally invasive dentistry is being widely practiced. The center stone is to be as conservative as possible to minimize unnecessary removal of healthy tooth structure. In prosthodontics the patients have generalized and combined nature of diseases.

External Validation of an AI mHealth Tool for Gingivitis Detection among Older Adults at Daycare Centers: A Pilot Study.

Objectives: Periodontal disease is a significant public health concern among older adults due to its relationship with tooth loss and systemic health disease. However, there are numerous barriers that prevent older adults from receiving routine dental care, highlighting the need for innovative screening tools at the community level. This pilot study aimed first, to evaluate the accuracy of GumAI, a new mHealth tool that uses AI and smartphones to detect gingivitis, and the user acceptance of personalized oral hygiene instructions provided through the new tool, among older adults in day-care community centers.

Diagnosis of lung cancer using salivary miRNAs expression and clinical characteristics.

Objective: Lung cancer (LC), the primary cause for cancer-related death globally is a diverse illness with various characteristics. Saliva is a readily available biofluid and a rich source of miRNA. It can be collected non-invasively as well as transported and stored easily.

Propolis mouthwashes efficacy in managing gingivitis and periodontitis: a systematic review of the latest findings.

Background And Objectives: Gingivitis and periodontitis are common periodontal diseases that can significantly harm overall oral health, affecting the teeth and their supporting tissues, along with the surrounding anatomical structures, and if left untreated, leading to the total destruction of the alveolar bone and the connective tissues, tooth loss, and other more serious systemic health issues. Numerous studies have shown that propolis can help reduce gum inflammation, inhibit the growth of pathogenic bacteria, and promote tissue regeneration, but with varying degrees of success reported. For this reason, this comprehensive systematic review aims at finding out the truth concerning the efficacy of propolis mouthwashes in treating gingivitis and periodontitis, as its main objective.

Automatic segmentation of cortical bone microstructure: Application and analysis of three proximal femur sites.

Osteoporosis is the most common bone metabolic unbalance, leading to fragility fractures, which are known to be associated with structural changes in the bone. Cortical bone accounts for 80 % of the skeleton mass and undergoes remodeling throughout life, leading to changes in its thickness and microstructure. Although many studies quantified the different cortical bone structures using CT techniques (3D), they are often realised on a small number of samples.

The Application of Resolvin D1-Loaded Gelatin Methacrylate in a Rat Periodontitis Model.

To evaluate the drug release, cytocompatibility with periodontal ligament cells (PDLCs), and therapeutic efficacy of GelMA hydrogel loaded with resolvin D1 (RvD1) in treating rat periodontal inflammation and alveolar bone damage. An RvD1 complexed with GelMA was prepared, and its release kinetics and compatibility with PDLCs were assessed. Rats with induced periodontitis were treated weekly with topical applications of vehicle, GelMA, RvD1, or RvD1 complexed with GelMA for four weeks.

Evaluation of Biologics ACE2/Ang(1-7) Encapsulated in Plant Cells for FDA Approval: Safety and Toxicology Studies.

For several decades, protein drugs (biologics) made in cell cultures have been delivered as sterile injections, decreasing their affordability and patient preference. Angiotensin Converting Enzyme 2 (ACE2) gum is the first engineered human blood protein expressed in plant cells approved by the FDA without the need for purification and is a cold-chain and noninvasive drug delivery. This biologic is currently being evaluated in human clinical studies to debulk SARS-CoV-2 in the oral cavity to reduce coronavirus infection/transmission (NCT00543318).

Edentulism or Poor Oral Hygiene: Which Is the Stronger Predictor for All-Cause Mortality?

: All-cause mortality consisting of several heterogeneous subgroups does not have a well-defined set of risk factors. Despite the well-described role of oral hygiene on mortality, the association between the condition of the existing dentition and mortality remains unclear. Therefore, we embarked on the current study to assess the association of oral hygiene self-care (OHS) with all-cause mortality.

Epidemiological Characteristics of Hospitalized Burn Patients-A 10-Year Retrospective Study in a Major Burn Center in Serbia.

Background: Many European countries' epidemiological data on burns were analyzed. This research aimed to analyze the key epidemiological characteristics of hospitalized burn patients in Serbia's major burn unit over 10 years, as well as to create the very first national epidemiological dataset with the basic requirements for future epidemiological studies.

Methods: A retrospective cross-sectional study was conducted, and demographic, clinical, and burn characteristics, as well as predictors of mortality, were analyzed.

Production of Amyloid-β in the Aβ-Protein-Precursor Proteolytic Pathway Is Discontinued or Severely Suppressed in Alzheimer's Disease-Affected Neurons: Contesting the 'Obvious'.

A notion of the continuous production of amyloid-β (Aβ) via the proteolysis of Aβ-protein-precursor (AβPP) in Alzheimer's disease (AD)-affected neurons constitutes both a cornerstone and an article of faith in the Alzheimer's research field. The present Perspective challenges this assumption. It analyses the relevant empirical data and reaches an unexpected conclusion, namely that in AD-afflicted neurons, the production of AβPP-derived Aβ is either discontinued or severely suppressed, a concept that, if proven, would fundamentally change our understanding of the disease.

Antibiotic Prophylaxis Prescribing Practices for Dental Implant Placement in Croatia: A Questionnaire-Based Cross-Sectional Study.

: This study aimed to explore antibiotic prescribing practices for dental implant placement in Croatia. : We conducted a cross-sectional questionnaire-based study including dentists in Croatia who perform dental implant therapy. The questionnaire assessed the dentists' age, working experience, education level, and whether they use antibiotics for dental implant placement, as well as the choice of antibiotics, timing, and reasons for antibiotics use.

Association between oral health-related quality of life and physical frailty among community-dwelling older adults: A 2-year longitudinal study.

Background: Frailty is a major health concern among older adults, and its association with oral health-related quality of life (OHRQoL) remains underexplored in longitudinal studies.

Objective: To investigate the association between baseline OHRQoL and physical frailty incidence at a 2-year follow-up in community-dwelling older adults.

Design: Prospective longitudinal study.

Gender Differences in Barriers in Career Development Among a Cohort of Dental Researchers. A Cross-Sectional Study.

Background: This cross-sectional study investigated gender differences in barriers to career development among dental researchers and between academic and non-academic women.

Methods: An anonymous 34-item survey assessing barriers to career development and workplace obstacles (14 items), along with demographic/occupation characteristics (22 items), was distributed among dental researchers at the Women In Science Network meetings at 2024 AADOCR/IADR General Session (QR code) and through AADOCR/IADR discussion board (online platform). Differences in barriers and workplace obstacles were analyzed between women and men with chi-square tests; comparisons were repeated among women working within versus outside academia.

Mandibular hybrid odontogenic tumor.

Background: Hybrid Odontogenic Tumors (HOT) are defined by the presence of two or more independent odontogenic tumors that originate from and affect the same maxillofacial site.

Methods: The present study is the first case report of a mandibular HOT consisting of Ameloblastoma, Calcifying Epithelial Odontogenic Tumor, and Ameloblastic Fibroma.

Case Report: A 37-year-old otherwise healthy male presented with the chief complaint of swelling in the right mandibular body.

The Influence of Posterior Class II Composite Restoration Location and Techniques on Marginal Sealing.

: The success of treatment and prevention for secondary caries hinges significantly on the techniques employed in Class II composite restoration. Additionally, the location of the restored tooth within the oral cavity has emerged as a potential factor determining the quality of the restoration. A comprehensive understanding of these interrelated variables is crucial for advancing the efficacy and durability of dental composite restorations.