11 results match your criteria: "School of Computational and Communication Sciences and Engineering[Affiliation]"

Optimal control of a two-group malaria transmission model with vaccination.

Netw Model Anal Health Inform Bioinform

December 2022

School of Computer Science and Applied Mathematics, University of the Witwatersrand, Private Bag 3, Wits 2050, Johannesburg, South Africa.

Malaria is a vector-borne disease that poses major health challenges globally, with the highest burden in children less than 5 years old. Prevention and treatment have been the main interventions measures until the recent groundbreaking highly recommended malaria vaccine by WHO for children below five. A two-group malaria model structured by age with vaccination of individuals aged below 5 years old is formulated and theoretically analyzed.

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Modelling COVID-19 in Senegal and China with count autoregressive models.

Model Earth Syst Environ

August 2022

School of Computer Science and Applied Mathematics, University of the Witwatersrand, Private Bag 3, Wits 2050, Johannesburg, South Africa.

COVID-19 is a global health burden. We propose to model the dynamics of COVID-19 in Senegal and in China by count time series following generalized linear models. One of the main properties of these models is that they can detect potentials trends on the contagion dynamics within a given country.

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Mathematical modeling and optimal control of SARS-CoV-2 and tuberculosis co-infection: a case study of Indonesia.

Model Earth Syst Environ

July 2022

School of Computer Science and Applied Mathematics, University of the Witwatersrand, Private Bag 3, Wits 2050, Johannesburg, South Africa.

A new mathematical model incorporating epidemiological features of the co-dynamics of tuberculosis (TB) and SARS-CoV-2 is analyzed. Local asymptotic stability of the disease-free and endemic equilibria are shown for the sub-models when the respective reproduction numbers are below unity. Bifurcation analysis is carried out for the TB only sub-model, where it was shown that the sub-model undergoes forward bifurcation.

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Dynamic of a two-strain COVID-19 model with vaccination.

Results Phys

August 2022

School of Computational and Applied Mathematics, University of the Witwatersrand, Johannesburg, Private Bag 3, Wits 2050, South Africa.

COVID-19 is a respiratory illness caused by an ribonucleic acid (RNA) virus prone to mutations. In December 2020, variants with different characteristics that could affect transmissibility emerged around the world. To address this new dynamic of the disease, we formulate and analyze a mathematical model of a two-strain COVID-19 transmission dynamics with strain 1 vaccination.

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HIV and COVID-19 co-infection: A mathematical model and optimal control.

Inform Med Unlocked

May 2022

School of Computer Science and Applied Mathematics, University of the Witwatersrand, Private Bag 3, Wits 2050, Johannesburg, South Africa.

A new mathematical model for COVID-19 and HIV/AIDS is considered to assess the impact of COVID-19 on HIV dynamics and vice-versa. Investigating the epidemiologic synergy between COVID-19 and HIV is important. The dynamics of the full model is driven by that of its sub-models; therefore, basic analysis of the two sub-models; HIV-only and COVID-19 only is carried out.

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Modeling COVID-19 daily cases in Senegal using a generalized Waring regression model.

Physica A

July 2022

School of Computer Science and Applied Mathematics, University of the Witwatersrand, Private Bag 3, Wits 2050, Johannesburg, South Africa.

The rapid spread of the COVID-19 pandemic has triggered substantial economic and social disruptions worldwide. The number of infection-induced deaths in Senegal in particular and West Africa in general are minimal when compared with the rest of the world. We use count regression (statistical) models such as the generalized Waring regression model to forecast the daily confirmed COVID-19 cases in Senegal.

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The COVID-19 epidemic is an unprecedented and major social and economic challenge worldwide due to the various restrictions. Inflow of infective immigrants have not been given prominence in several mathematical and epidemiological models. To investigate the impact of imported infection on the number of deaths, cumulative infected and cumulative asymptomatic, we formulate a mathematical model with infective immigrants and considering vaccination.

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Optimal control analysis of a COVID-19 and tuberculosis co-dynamics model.

Inform Med Unlocked

January 2022

School of Computational and Communication Sciences and Engineering, Nelson Mandela African Institution of Science and Technology, P.O. Box 447, Arusha, Tanzania.

Tuberculosis and COVID-19 are among the diseases with major global public health concern and great socio-economic impact. Co-infection of these two diseases is inevitable due to their geographical overlap, a potential double blow as their clinical similarities could hamper strategies to mitigate their spread and transmission dynamics. To theoretically investigate the impact of control measures on their long-term dynamics, we formulate and analyze a mathematical model for the co-infection of COVID-19 and tuberculosis.

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Impact of environmental transmission and contact rates on Covid-19 dynamics: A simulation study.

Inform Med Unlocked

December 2021

School of Computational and Communication Sciences and Engineering, Nelson Mandela African Institute of Science and Technology, P.O. Box 447, Arusha, Tanzania.

The emergence of the COVID-19 pandemic has been a major social and economic challenge globally. Infections from infected surfaces have been identified as drivers of Covid-19 transmission, but many epidemiological models do not include an environmental component to account for indirect transmission. We formulate a deterministic Covid-19 model with both direct and indirect transmissions.

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COVID-19 and dengue co-infection in Brazil: optimal control and cost-effectiveness analysis.

Eur Phys J Plus

October 2021

School of Computer Science and Applied Mathematics, University of the Witwatersrand, Private Bag 3, Wits 2050, Johannesburg, South Africa.

A mathematical model for the co-interaction of COVID-19 and dengue transmission dynamics is formulated and analyzed. The sub-models are shown to be locally asymptotically stable when the respective reproduction numbers are below unity. Using available data sets, the model is fitted to the cumulative confirmed daily COVID-19 cases and deaths for Brazil () from February 1, 2021 to September 20, 2021.

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A Mathematical Model of COVID-19 with Vaccination and Treatment.

Comput Math Methods Med

September 2021

School of Computational and Communication Sciences and Engineering, Nelson Mandela African Institution of Science and Technology, P.O. Box 447, Arusha, Tanzania.

We formulate and theoretically analyze a mathematical model of COVID-19 transmission mechanism incorporating vital dynamics of the disease and two key therapeutic measures-vaccination of susceptible individuals and recovery/treatment of infected individuals. Both the disease-free and endemic equilibrium are globally asymptotically stable when the effective reproduction number () is, respectively, less or greater than unity. The derived critical vaccination threshold is dependent on the vaccine efficacy for disease eradication whenever () > 1, even if vaccine coverage is high.

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