4,733 results match your criteria: "School of Chemistry and Molecular Engineering[Affiliation]"

Enantioselective Excited-State Nazarov Reaction: A Relay Strategy of Electrocyclization and Parallel Kinetic Resolution.

Org Lett

December 2024

Shanghai Key Laboratory of Green Chemistry and Chemical Processes, State Key Laboratory of Petroleum Molecular & Process Engineering, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200050, China.

We report herein the enantioselective photoinduced Nazarov reaction using a relay strategy of an electrocyclization, followed by parallel kinetic resolution (PKR). No enantioselectivity was observed during electrocyclization due to weak coordination between chiral ligands and the substrate's carbonyl group. However, PKR was successfully achieved in the deprotonation step with a bifunctional chiral thiourea ligand.

View Article and Find Full Text PDF

Probing Cell Membrane Tension Using DNA Framework-Encoded Vibration-Induced Emission Molecular Assemblies.

J Am Chem Soc

December 2024

School of Chemistry and Chemical Engineering, Frontiers Science Center for Transformative Molecules and National Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai 200240, China.

Mechanosensitive fluorescent probes are valuable tools for detecting changes in cellular mechanics and viscosity. While numerous mechanosensitive probes have been developed, the construction of molecular assemblies for probing cellular mechanics remains largely unexplored, possibly due to the challenges of designing assemblies with synergistic and integrated functionalities. Here, we report the design and synthesis of mechanosensitive molecular assemblies by integrating DNA frameworks with vibration-induced emission (VIE) probes to enable live-cell membrane tension imaging.

View Article and Find Full Text PDF

Visible light-induced cascade annulation of sulfoxonium ylides with azides for the synthesis of 2-trifluoromethyl indoles.

Chem Commun (Camb)

December 2024

Shanghai Key Laboratory of Functional Materials Chemistry, Key Laboratory for Advanced Materials, School of Chemistry and Molecular Engineering, East China University of Science & Technology, Shanghai 200237, China.

An efficient protocol was reported for the synthesis of 2-trifluoromethyl indoles through visible-light-promoted intermolecular cyclization of sulfoxonium ylides with azides, without the need for external photocatalysts, transition metals, or bases. The formation of 2-trifluoromethyl indoles involves an intriguing cascade process including azide rearrangement, intermolecular nucleophilic addition, and visible-light-promoted cyclization of a key intermediate. The protocol features high efficiency, mild conditions, excellent substrate compatibility and good regioselectivity.

View Article and Find Full Text PDF

Colloidal substrate-facilitated synthesis of gold nanohelices.

J Colloid Interface Sci

December 2024

Institute of Advanced Synthesis (IAS) and School of Chemistry and Molecular Engineering, Jiangsu National Synergetic Innovation Centre for Advanced Materials, Nanjing Tech University, 30 Puzhu South Road, Nanjing 211816, PR China. Electronic address:

Helical nanostructures have unique optical and mechanical properties, yet their syntheses had always been quite challenging. Various symmetry-breaking mechanisms such as chiral templates, strain-restriction and asymmetric ligand-binding have been developed to induce the helical growth at nanoscale. In this work, with neither chiral ligands nor templates, gold (Au) nanohelices were synthesized via a facile wet-chemical method, through an asymmetric Active Surface Growth facilitated by colloidal silica nanoparticles (NPs).

View Article and Find Full Text PDF

Vacuum-Assisted Confined Growth of MOF@COF Composite Membranes with Enhanced Hydrogen Permselectivity.

Angew Chem Int Ed Engl

December 2024

State Key Laboratory of Molecular & Process Engineering, Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal University, 500, Dongchuan Road, Shanghai, 200241, China.

Article Synopsis
  • Covalent organic frameworks (COFs) have potential for creating high-quality separation membranes but face challenges in gas separation due to larger pore sizes.
  • The study introduces a novel method by embedding the metal-organic framework (MOF) ZIF-8 within TB-COF to enhance gas separation properties.
  • The resulting ZIF-8@TB-COF membrane achieves significantly increased hydrogen selectivity for separating gas mixtures compared to traditional COF membranes, demonstrating the effectiveness of this new synthesis approach.
View Article and Find Full Text PDF

Teaching spin symmetry while learning neural network wave functions.

Nat Comput Sci

December 2024

Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, Shanghai Frontiers Science Center of Molecule Intelligent Syntheses, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai, China.

View Article and Find Full Text PDF

Interface Electron Transfer Direction-Tuned Urea Electrooxidation Over Multi-Interface Nickel Sulfide Heterojunctions.

Small

December 2024

Key Laboratory of Advanced Civil Engineering Materials of Ministry of Education, School of Materials Science and Engineering, Tongji University, Shanghai, 201804, China.

Article Synopsis
  • The study introduces two types of nickel sulfide (NiS) heterojunctions embedded in nitrogen-doped carbon nanotubes that act as effective catalysts for urea oxidation reactions.
  • The performance of these catalysts is enhanced by adjusting the direction of electron transfer at their interfaces, with one configuration achieving a significant current density, indicating improved efficiency in the reaction process.
View Article and Find Full Text PDF

Attributed to their unique dynamic planar chirality, pillar[n]arenes, particularly pillar[5]arenes, have evolved as promising platforms for diverse applications such as circularly polarized luminescence (CPL) emitters. However, due to the unit flipping and swing, the achievement of excellent CPL performances of pillar[5]arenes in solution state remains a formidable challenge. To deal with this key issue, a mechanically locking approach has been successfully developed, leading to boosted dissymmetry factor (g) values of pyrene-tiaraed pillar[5]arenes up to 0.

View Article and Find Full Text PDF

Efficient Quasi-Homogenous Photocatalysis Enabled by Molecular Nanophotocatalysts with Donor-Acceptor Motif.

Adv Mater

December 2024

Key Laboratory for Advanced Materials and Institute of Fine Chemicals, Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, Frontiers Science Center for Materiobiology and Dynamic Chemistry, School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai, 200237, China.

Polymer semiconductors have attracted much attention for photocatalytic hydrogen evolution, but they typically exhibit micrometer-sized particles in water-suspension, causing severe loss in light absorption and exciton recombination. Here a molecular nanophotocatalyst featuring a donor-acceptor motif is presented that solution is processed via a facile stirring nanoprecipitation method assisted by hydrophilic surfactants, enabling an efficient quasi-homogenous hydrogen evolution. In contrast to the original bulk powder (heterogeneous system), these quasi-homogenous nanophotocatalysts exhibit significantly improved light-harvesting, water-wettability, and exciton dissociation, resulting in distinctly enhanced (by four-order-of-magnitude) photocatalytic hydrogen evolution rate.

View Article and Find Full Text PDF

Deep and comprehensive understanding of the intricate biochemical processes mediated by HS ( ≥ 1), but not HS, is of paramount importance. A few fluorescent probes have been developed with the intention of addressing this issue. However, there is currently no evidence of any activatable NIR-II fluorescent probes for HS-specific imaging over HS.

View Article and Find Full Text PDF

Circularly polarized luminescence (CPL) materials with precisely controlled emission colors and handedness are highly desirable for their promising applications in advanced optical technologies, but it is rather challenging to obtain them primarily due to the lack of convenient, powerful, and universal preparation strategies. Herein, we report a simple yet versatile solution route for constructing multicolor CPL materials with controllable handedness from nonchiral luminescent charge-transfer (CT) complexes through co-assembly with chiral N-terminal aromatic amino acids. The resulting ternary co-assemblies exhibit obvious CPL signals from 489 to 601 nm, covering from blue green and yellow to orange-red.

View Article and Find Full Text PDF

Evolution of Supramolecular Coordination Assemblies Visually Monitored by Time-Dependent Multicolor Fluorescence.

Angew Chem Int Ed Engl

December 2024

Key Laboratory for Advanced Materials, Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China.

Article Synopsis
  • Supramolecular coordination assemblies are crucial in material science and biology, but most current examples lack adaptability due to being thermodynamically controlled.
  • This research introduces non-equilibrium coordination assembly systems that evolve over time, transitioning from metastable fiber structures to stable nanosheets with the help of zinc ions.
  • The evolution process can be tracked using multicolor fluorescence and can be influenced by external factors, showcasing a versatile approach applicable with other ions like Ca, Mg, and Al.
View Article and Find Full Text PDF

The conventional molecular immunogenic cell death (ICD) inducers suffer from poor biocompatibility and unsatisfactory efficacy. Here, a biocompatible nanosized covalent organic framework (nCOF)-based pyroelectric catalyst (denoted as TPAD-COF NPs) is designed for pyroelectric catalysis-activated in situ immunotherapy. TPAD-COF NPs confine organic pyroelectric molecules to rigid TPAD-COF NPs to substantially reduce aggregation and enhance biocompatibility, thus improving pyroelectrocatalytic efficiency.

View Article and Find Full Text PDF

Intermediate-regulated dynamic restructuring at Ag-Cu biphasic interface enables selective CO electroreduction to C fuels.

Nat Commun

November 2024

Department of Chemistry, iChEM (Collaborative Innovation Center of Chemistry for Energy Materials), Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Fudan University, Shanghai, China.

A bimetallic heterostructure has been shown effective to enhance the multi-carbon (C) product selectivity in CO electroreduction. Clarifying the interfacial structure under electrolysis and its decisive role in the pathway selection are crucial, yet challenging. Here, we conceive a well-defined Ag-Cu biphasic heterostructure to understand the interfacial structure-steered product selectivity: The Cu-rich interface prefers ethylene, while the dominant product switch to alcohols with an increasing Ag fraction, and finally to CO as Ag occupying the main surface.

View Article and Find Full Text PDF

Ligand-enabled Ni-catalysed dicarbofunctionalisation of alkenes with diverse native functional groups.

Nat Commun

November 2024

State Key Laboratory of Organometallic Chemistry and Shanghai-Hong Kong Joint Laboratory in Chemical Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CAS), Shanghai, PR China.

The transition metal-catalysed dicarbofunctionalisation of unactivated alkenes normally requires exogenous strong coordinated directing groups, thus reducing the overall reaction efficiency. Here, we report a ligand-enabled Ni(II)-catalysed dicarbofunctionalisation of unactivated alkenes with aryl/alkenyl boronic acids and alkyl halides as the coupling partners with a diverse range of native functional groups as the directing group. This dicarbofunctionalisation protocol provides an efficient and direct route towards vicinal 1,2-disubstituted alkanes using primary, secondary, tertiary amides, sulfonamides, as well as secondary and tertiary amines under redox-neutral conditions that are challenging to access through conventional methods.

View Article and Find Full Text PDF

Reversible Circularly Polarized Luminescence Inversion and Emission Color Switching in Photo-Modulated Supramolecular Polymer for Multi-Modal Information Encryption.

J Am Chem Soc

December 2024

Shanghai Key Laboratory of Chemical Assessment and Sustainability, School of Chemical Science and Engineering, Advanced Research Institute, Tongji University, Shanghai 200092, P. R. China.

Constructing circularly polarized luminescence (CPL) materials that exhibit dynamic handedness inversion and emissive color modulation for multimodal information encryption presents both a significant challenge and a compelling opportunity. Here, we have developed a pyridinethiazole acrylonitrile-cholesterol derivative (Z-PTC) that exhibits wavelength-dependent photoisomerization and photocyclization, enabling dynamic handedness inversion and emissive color modulation in supramolecular assemblies with decent CPL activity. Coordination with Ag ions form the Z-PTC Ag supramolecular polymer (SP), which assembles into nanotubes displaying enhanced positive yellow-green CPL.

View Article and Find Full Text PDF

Biogel Library-Accelerated Discovery of All-Natural Bioelectronics.

ACS Sens

December 2024

School of Chemistry and Molecular Engineering, In Situ Devices Research Center, Shanghai Key Laboratory for Urban Ecological Processes and Eco-Restoration, East China Normal University, Shanghai 200241, China.

Biogels prepared from natural biopolymers are ideal candidates for constructing bioelectronics from the perspective of commercialization and environmental sustainability. However, discovering all-natural biogels that meet specific properties, such as mechanical properties, optical transparency, and stability, remains challenging. Here, our study introduces a revolutionary biogel library, a novel resource that significantly accelerates the discovery and application of suitable all-natural biogel materials for bioelectronics.

View Article and Find Full Text PDF

Proteolysis-regulated excited state electron transfer of AgS/In(OH)@BSA nanocomposites for fluorescence-photoelectrochemistry dual-mode biosensing of heparin.

Biosens Bioelectron

February 2025

Jiangsu Collaborative Innovation Center of Biomedical Functional Materials and Jiangsu Key Laboratory of Biofunctional Materials, School of Chemistry and Materials Science, Nanjing Normal University, Nanjing, 210023, PR China; School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing, 211816, PR China. Electronic address:

Sharing the same photoexcitation process, fluorescence (FL) and photoelectrochemistry (PEC) accomplish optical-optical and optical-electrochemical switches respectively, and are both widely used in diverse fields. However, since FL and PEC are mutually exclusive in principle, it is difficult to obtain intense FL and PEC responses in a system, limiting FL-PEC dual-mode applications. In this study, AgS quantum dots (QDs) and In(OH) nanoblocks (NBs) are simultaneously synthesized by BSA-templated bio-mineralization, and the excited state electrons of AgS/In(OH)@BSA nanocomposites (NCs) are further regulated by a proteolysis process.

View Article and Find Full Text PDF

Synthesis of P(V)-Stereogenic Phosphorus Compounds via Organocatalytic Asymmetric Condensation.

J Am Chem Soc

December 2024

State Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang 550025, China.

Enantioenriched phosphorus(V)-stereogenic compounds, featuring a pentavalent phosphorus atom as the stereogenic center, are crucial in various natural products, drugs, bioactive molecules, and catalysts/ligands. While a handful of stereoselective synthetic approaches have been developed, achieving direct stereocontrol at the phosphorus atom through catalytic generation of phosphorus(V)-heteroatom bonds continues to be a formidable challenge. Here, we disclose an organocatalytic asymmetric condensation strategy that employs a novel activation mode of stable feedstock phosphinic acids by the formation of mixed phosphinic anhydride as the reactive species to facilitate further catalyst-controlled asymmetric P-O bond formations, involving a dynamic kinetic asymmetric transformation (DYKAT) process with alcohol nucleophiles via a cinchonidine-derived bifunctional catalyst.

View Article and Find Full Text PDF

Regulating socketed geometry of nanoparticles on perovskite oxide supports for enhanced stability in oxidation reactions.

Nat Commun

November 2024

State Key Laboratory of Green Chemical Engineering and Industrial Catalysis, School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai, PR China.

Heterogeneous catalysts with highly dispersed active particles on supports often face stability challenges during high-temperature industrial applications. The ex-solution strategy, which involves in situ extrusion of metals to form socketed particles, shows potential for addressing this stability issue. However, a deeper understanding of the relationship between the socketed geometry of these partially embedded nanoparticles and their catalytic performance is still lacking.

View Article and Find Full Text PDF

Progress in Pyrene-4,5,9,10-Tetraone-Based Organic Electrode Materials for Rechargeable Batteries.

ChemSusChem

November 2024

Shanghai Key Laboratory of Materials Protection and Advanced Materials in Electric Power, College of Environmental and Chemical Engineering, Shanghai University of Electric Power, Shanghai, 200090, China.

Article Synopsis
  • Pyrene-4,5,9,10-tetraone (PTO) is a coal tar derivative with potential as a sustainable organic electrode due to its high capacity and redox robustness, but it faces challenges like poor cycling stability and low electrical conductivity.
  • * Recent strategies aim to reduce PTO's solubility in organic electrolytes to prevent issues like self-discharge and shuttle effects, thus enhancing its performance in batteries.
  • * The review discusses structural characteristics of PTO, compares methods to mitigate its solubility issues, explores the design of polymer electrode materials, and identifies future challenges for improving PTO and similar organic electrode materials in energy storage.
View Article and Find Full Text PDF

Integration of a Raman spectroscopic platform based on online sampling to monitor chemical reaction processes.

Anal Methods

December 2024

School of Chemistry and Molecular Engineering, Shanghai Key Laboratory of Functional Materials Chemistry, Research Centre of Analysis and Test, East China University of Science and Technology, Shanghai 200237, China.

During the pharmaceutical synthesis process, it is essential to control the reaction time to avoid by-product formation and the reduction of yield. In this study, a Raman spectroscopic platform based on online sampling was integrated to collect Raman spectra in real time and realize process monitoring. Considering its attractive features of strong light transmittance and resistance to acids, alkalis and high temperatures, polyfluoroalkoxy (PFA) tubes rather than cuvette-type flow cells or similar devices were used to transfer solutions and as a flow cell for collecting Raman spectra, therefore not requiring an Raman probe, and significantly reducing the cost of equipment.

View Article and Find Full Text PDF

A Helical Tubular Dyad of [9]Cycloparaphenylene: Synthesis, Chiroptical Properties and Post-Functionalization.

Angew Chem Int Ed Engl

November 2024

Key Laboratory of Photochemical Conversion and Optoelectronic Materials, CAS-HKU Joint Laboratory on New Materials, Technical Institute of Physics and Chemistry, School of Future Technology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing, 100190, China.

The bottom-up synthesis of discrete tubular molecules that mimic the structural features of carbon nanotubes has been a long-standing pursuit for synthetic chemists. As the shortest segments of armchair-type carbon nanotubes, cycloparaphenylenes are regarded as ideal macrocyclic building blocks for achieving this goal. Here we report the synthesis of a helical tubular molecule featuring three diyne linkers between two site-specifically functionalized [9]cycloparaphenylenes.

View Article and Find Full Text PDF

MoP assists the promotion on FeP and FeN for oxygen reduction and zinc-air battery.

J Colloid Interface Sci

March 2025

State Key Laboratory of Catalysis & Dalian National Laboratory for Clean Energy, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China; Institute of Catalysis for Energy and Environment, College of Chemistry and Chemical Engineering, Shenyang Normal University, Shenyang 110034, China; University of Chinese Academy of Sciences, Beijing, China. Electronic address:

It is of great significance but remains challenging to simultaneously development cost-effective and efficient non-noble metal electrocatalysts (NNMEs) for oxygen reduction reaction (ORR) in both alkaline and acidic solutions. In current work, a multi-component synergism system is developed, which is comprised of molybdenum phosphide (MoP) shell onto iron phosphide clusters anchored on carbon matrixes that embedded with numerous FeN species (MoP/FeP-FeN). The optimized MoP/FeP-FeN electrocatalyst delivers a synergistic enhancement in both alkaline and acidic ORR performances: E: 0.

View Article and Find Full Text PDF

The development of efficient and robust catalysts for hydrogen evolution reaction is crucial for advancing the hydrogen economy. In this study, we demonstrate that ultra-low coordinated hollow PtRuNi-O nanocages exhibit superior catalytic activity and stability across varied conditions, notably surpassing commercial Pt/C catalysts. Notably, the PtRuNi-O catalysts achieve current densities of 10 mA cm at only 19.

View Article and Find Full Text PDF