Natural Kaurane-class of Diterpenoid Alkaloids: Structure, Distribution, and Bioactivities.

Kaurane-class diterpenoid alkaloids (DAs), an important group of C20-DAs, include mainly veatchine-, napelline-, anopterine- and tricalysiamide-type DAs and several types of DAs with novel skeletons discovered in recent years. To date, approximately 81 compounds belonging to this class of DAs have been isolated from plants in 5 families and 7 genera. Among them, Aconitum is the most important source of this class of DAs.