An exploratory single-arm open-label clinical study to evaluate the combined effect of Vamana and Sarasvata Churna in reducing excessive daytime sleepiness.

Background: Excessive Daytime Sleepiness (EDS) is inferred as persistent sleepiness and often a general lack of energy during the day even after apparently adequate or even prolonged nighttime sleep. The subjects may not be identifying excessive daytime sleepiness but may present as feeling tired, lack of energy etc. They may seem apparently healthy and without any other systemic illness.

Ayurveda in the integrative management of bovine secondary recumbency-a case report.

Downer cow syndrome, or secondary recumbency, is a condition primarily affecting dairy cows, where the animal is unable to rise and stand, due to unknown cause. It is usually associated with poor prognosis. Terminal downers are euthanized in most countries.

Jasminum grandiflorum oral gel as an add-on to standard of care in radiation induced grade 2 oral mucositis - an open label pilot clinical trial.

Background: Radiation-induced oral mucositis is one of the most critical dose-limiting toxicities associated with radiation therapy for oral cancer which can result in treatment interruption and compromise the quality of the life of cancer patients. Jati (Jasminum grandiflorum) is used in Ayurveda to treat oral conditions like stomatitis and mouth ulcers.

Objective: To test the feasibility of Jati oral gel as an add on therapy in grade 2 radiation-induced oral mucositis.

Comparing the efficacy of Agnikarma with therapeutic ultrasound in the management of tennis elbow - A randomised controlled preliminary study.

Background: Tennis elbow is a common musculoskeletal disease of elbow and causes restricted movement of forearm. Various treatment modalities like NSAID, corticosteroid injection, counter bracing, physiotherapy, surgery etc are available but safety and efficacy of one treatment over another is under research. Ayurveda classifies this condition as Snayugata vata.

Randomized, Double-Blind, Placebo-Controlled, Clinical Study of Passiflora incarnata in Participants With Stress and Sleep Problems.

Background and objectives SIVI is a standardized extract prepared using the aerial parts of developed to enhance the quality of sleep. ​​​​​​The objective of the present study was to the evaluate efficacy and safety of SIVI ( extract) in the management of stress and sleep problems in Indian participants in a randomized, double-blind, placebo-controlled, clinical study. Materials and methods A total of 65 participants with stress and insomnia were randomized to two groups with 32 in the SIVI ( extract) group and 33 in the placebo group.

Ayurvedic management of a refractory skin disease clinically diagnosed as Cutaneous Lichen Planus-A case report.

This study reports the successful management of a recurrent, refractory skin disease diagnosed clinically as Cutaneous Lichen Planus (CLP) in a female patient with Ayurvedic treatment. A 42-year-old home maker from Coimbatore presented with blackish-red pigmented skin rashes and white streaks. Though mucous membranes were not affected, she did not respond to homoeopathic and biomedical treatment.

Rapid improvement of oculomotor nerve function with ayurvedic treatment in traumatic diplopia - A case report.

Diplopia or double vision has many aetiologies and often presents to the ophthalmologist. The causes of diplopia may be ocular or neurogenic in origin. Any trauma to the eyes in the form of blow-out fractures causes diplopia by damaging the third nerve.

Integrative management of insomnia during cancer chemotherapy: A case report.

Introduction: Insomnia is common among cancer patients, affecting about 50% undergoing cancer treatment. Insomnia can be due to various reasons, such as physical-pain, psychological-distress and medication side-effects. Insomnia has significant impact on quality of life of cancer patients.

A scoping review of Ayurvedic rasayana adaptogens in oncology.

Introduction: Rasayanas are Ayurvedic natural products that have adaptogenic effects. The extensive research on rasayanas in oncology is not currently well summarized. The aim of this review is to investigate the range and nature of the current body of research, identify gaps in knowledge, and to summarize the existing literature as it relates to Ayurvedic rasayanas and oncology.

Ayurveda research: Emerging trends and mapping to sustainable development goals.

Ayurveda is India's prominent traditional medical system. The World Health Organization has stated the need for more evidence and data from conventional medicine methods to inform policymakers, regulatory bodies, healthcare stakeholders, and the public about its safe, effective, and equitable use. This study aims to provide a comprehensive analysis of the emerging trends in Ayurveda research, mapping research to the UN Sustainable Development Goals (SDG) and examining the impact of COVID-19.

Ayurvedic management central serous retinopathy - A case report.

Background: Central Serous Retinopathy (CSR) is an eye disease that causes visual impairment ascribable to fluid accumulation in the retina's macular area. CSR leads to the blurring of vision associated with metamorphopsia. The cause of the disease is unknown.

Ayurveda management of cystocele, uterine prolapse and weak pelvic floor strength-A case report.

Pelvic organ prolapse (POP) is the downward displacement of pelvic organs. The condition is very common in women and negatively affects their quality of life. The aging process reflects in the form of structural and functional weakness of the pelvic floor which leads to pelvic floor dysfunction (PFD).

Effective management of Colles fracture using Murivenna and Abha Guggulu - A case report.

Colles fracture is the commonest fracture encountered in orthopedic practice that demands prompt therapeutic intervention, and adequate follow-up to ensure complete healing. Various types of fractures, methods of reduction, and healing have been explained in the classical Ayurveda texts. These techniques are scientific and time-tested.

Nicotine Free Herbal Composition for Smoking De-Addiction - A Placebo Controlled, Double Blind, Randomized, Multicentric Clinical Study.

Background: Smoking is a major predisposing factor for many health problems including cancers, vascular disorders, etc., To quit smoking is the only solution to prevent them. Various medicinal and non-medicinal methods are used worldwide for the same.

Ayurvedic management of venous ulcer - a case report.

Vrana (ulcer), in Ayurveda is defined as a structural deformity in the skin and deeper structures (gaatra avachurnana), associated with ruja (pain), srava (discharge) etc and caused either by the vitiation of the doshas(humuors of the body) or by trauma. Vrana is basically of 2 types- Dushta vrana and Shudha vrana. Shudha Vrana (acute ulcer) is easily treatable, whereas Dushta vrana is a chronic ulcer, mostly unresponsive to any treatment.

Learnings from a veteran oncologist's long-standing efforts in integrative oncology.

Kerala's first medical oncologist, the erstwhile Dr. CP Mathew, has left a rich legacy in cancer patients' case diaries and medical records. These documents contain valuable information about his attempts to integrate Siddha and Ayurveda treatments to manage cancer.

A phytochemical-based medication search for the SARS-CoV-2 infection by molecular docking models towards spike glycoproteins and main proteases.

Identifying best bioactive phytochemicals from different medicinal plants using molecular docking techniques demonstrates a potential pre-clinical compound discovery against SARS-CoV-2 viral infection. The screening of bioactive phytochemicals with the two druggable targets of SARS-CoV-2 by simple precision/extra precision molecular docking methods was used to compute binding affinity at its active sites. phyllaemblicin and cinnamtannin class of phytocompounds showed a better binding affinity range (-9.

Management of Erythrodermic Psoriasis through Ayurveda - A Case Report.

Introduction: Psoriasis is a noninfectious chronic inflammatory skin disorder, characterized by well-defined erythematous plaques with silvery scales. In an ayurvedic perspective, we can compare this disease with Kitibha Kushta (a type of skin lesion) because most of its signs and symptoms mimic that of erythrodermic psoriasis.

Case Presentation: A 23-year-old patient diagnosed with psoriasis presented with erythematous overlapped patches all over the body, Auspitz sign, and pain associated with occasional itching sensation.

Integrative approach combining Ayurveda, counselling, Yoga and meditation with conventional management of Ankylosing Spondylitis - A case report.

Lifelong medications are required for symptomatic relief in Ankylosing Spondylitis (AS). We report the potential of an integrative approach in reducing dependence on steroids and pain medications in chronic AS. A 59-year-old HLA-B27 positive male patient suffering from AS for 40 years sought Ayurvedic treatment for relapse of pain, stiffness, fatigue, intermittent constipation and disturbed sleep.

Management of psoriasis with and as - a case report.

Objectives: Plaque psoriasis is very embarrassing condition of skin as it produces itchy rashes and scaly lesions which may not respond well to the treatment. It can be correlated with which is one among the 18 types of (skin diseases). Several corticosteroids for skin applications are used now a day's which gives only temporary relief.

Pharmacokinetics of solid lipid particles in healthy subjects.

Objectives: The anti-inflammatory activity of extracts (BSE) is well known. BSE comprises boswellic acids (BA) such as 3--acetyl-11-keto--boswellic acid (AKBA) and 11--boswellic acid (KBA) as major constituents. One of the limitations of BAs is their poor oral bioavailability.

Ayurvedic management of persistent hypoxia in a diabetic and hypertensive COVID-19 patient in the post-hospitalization period-A case report.

COVID-19 patients may require supplemental oxygen therapy at home after recovery from COVID-19. We report benefits of add on Ayurvedic intervention in a 75-year-old gentleman who was oxygen dependent post hospitalisation. He was earlier treated for COVID-19 related bilateral pneumonitis, Acute Respiratory Distress Syndrome and Acute Renal Failure.

Comparative hepatoprotective activity of detoxified roots of Plumbago zeylanica L. and Plumbago rosea L. in Wistar rats.

Background: Paracetamol (acetaminophen) toxicity is considered to be one of the major causes of drug-induced hepatic failure. Citraka (Plumbago rosea L. and Plumbago zeylanica L.