5,364 results match your criteria: "School of Applied Sciences[Affiliation]"

Upper Limit on the Photoproduction Cross Section of the Spin-Exotic π_{1}(1600).

Phys Rev Lett

December 2024

Thomas Jefferson National Accelerator Facility, Newport News, Virginia 23606, USA.

The spin-exotic hybrid meson π_{1}(1600) is predicted to have a large decay rate to the ωππ final state. Using 76.6  pb^{-1} of data collected with the GlueX detector, we measure the cross sections for the reactions γp→ωπ^{+}π^{-}p, γp→ωπ^{0}π^{0}p, and γp→ωπ^{-}π^{0}Δ^{++} in the range E_{γ}=8-10  GeV.

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Unlabelled: The use of pesticides in agricultural produce is continuously increasing and it raises the question of whether the food is safe or not. Only 0.1% of the sprayed pesticide reaches its target and the rest acts as a contaminant in soil and the environment, thus contaminating the future foods as well.

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Highly Green Fluorescent Carbon Dots from Gallic Acid: A Turn-On Sensor toward Pb Ions.

ACS Omega

January 2025

Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.

Carbon dots (CDs) are emerging novel fluorescent sensing nanomaterials owing to their tunable optical properties, biocompatibility, and eco-friendliness. Herein, we report a facile one-pot hydrothermal route for the synthesis of highly green fluorescent CDs using gallic acid (GA) as a single carbon source in ,-dimethylformamide (DMF) solvent, which serves as a nitrogen source and reaction medium. The optical properties of the synthesized GA-DMF CDs were systematically characterized by using UV-vis and photoluminescence spectroscopy, revealing strong green fluorescence.

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Bioactive Compounds from Vegetal Organs of Species (Dandelion) with Biomedical Applications: A Review.

Int J Mol Sci

January 2025

Institute of Doctoral Studies, Doctoral School of Applied Sciences, Doctoral Field:Biology, "Ovidius" University of Constanta, 58, Ion Voda Street, 900573 Constanta, Romania.

(dandelion) is a perennial flowering plant of the Asteraceae family that has spread globally and is well-known for its traditional uses. The aim of this work is to provide a detailed review of scientific literature on the genus from the last two decades, with particular emphasis on the biological and pharmacological characteristics of dandelions. The traditional use of species and their potential use in medicine are assessed.

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The complex signaling network within the breast tumor microenvironment is crucial for its growth, metastasis, angiogenesis, therapy escape, stem cell maintenance, and immunomodulation. An array of secretory factors and their receptors activate downstream signaling cascades regulating breast cancer progression and metastasis. Among various signaling pathways, the EGFR, ER, Notch, and Hedgehog signaling pathways have recently been identified as crucial in terms of breast cancer proliferation, survival, differentiation, maintenance of CSCs, and therapy failure.

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Diabetic foot, leg ulcers and decubitus ulcers affect millions of individuals worldwide leading to poor quality of life, pain and in several cases to limb amputations. Despite the global dimension of this clinical problem, limited progress has been made in developing more efficacious wound dressings, the design of which currently focusses on wound protection and control of its exudate volume. The present in vitro study systematically analysed seven types of clinically-available wound dressings made of different biomaterial composition and engineering.

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This study explores the relationship between forgiveness and interpersonal problem-solving skills among university students using a correlational design. The sample includes 443 students aged 18-26 from Mersin and Selçuk Universities, selected through convenience sampling. Data were collected using the Heartland Forgiveness Scale, the Interpersonal Problem-Solving Inventory, and a personal information form.

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This research examined the distinction between organic and conventional mango fruits, chips, and juice using portable near-infrared (NIR) spectroscopy. A comprehensive analysis was conducted on a sample of 100 mangoes (comprising 50 organic and 50 conventional) utilising a portable NIR spectrometer that spans a wavelength range from 900 to 1700 nm. The mangoes were assessed in their entirety and their juice and chip forms.

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Choanoflagellate species have been taxonomically divided upon the morphological and developmental basis of their extracellular coat (periplast). Species within the order Craspedida possess a purely organic periplast, whereas taxa of the order Acanthoecida have an additional silica based periplast termed the lorica. Whilst small-scale phylogenetic studies have recovered the two orders as monophyletic, recent phylogenomic analyses have rejected the monophyly of the craspedids.

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Background: Glioblastoma multiforme (GBM) is the most prevalent primary brain tumour, with an incidence of 2 per 100,000. The standard clinical treatments do not sufficiently target cell migration and invasion, leading to recurrence after surgical resection and resistance after chemotherapy and radiotherapy. Pre-clinical studies are being conducted to construct artificial substrates that can mimic the tumour microenvironment (TME) to prevent GBM cells from migrating along their primary route through blood vessels and white matter tracts.

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Energy crisis and environmental pollution are two central themes of contemporary research towards achieving sustainable development goals (SDGs). Material chemistry is the chief discipline that can resolve glitches in these areas through the appropriate design of chemical compounds with multifunctional properties. In this regard, two stable coordination polymers (CPs) were synthesised in this work using Zn(II) (3d) and Cd(II) (d) metal nodes with 1,4-benzenedicarboxylate () as the bridging ligand and monodentate pyridyl-N coordinated 9-fluoren-2-yl-pyridin-4-ylmethylene-amine (flpy) as the fluorogenic partner.

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Theoretical evaluation of the biological activity of hydrogen.

Med Gas Res

June 2025

Research Consultant, Water Fuel Engineering, Wakefield, UK.

Hydrogen (H2), the simplest and most ubiquitous molecule in the universe, has garnered significant scientific interest over the past two decades because of its potential as an effective antioxidant and anti-inflammatory agent. Traditionally considered inert, H2 is now being re-evaluated for its unique bioactive properties. H2 selectively neutralizes reactive oxygen and nitrogen species, mitigating oxidative stress without disrupting essential cellular functions.

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Women's health is related to several factors that include physical, mental, and reproductive health. Additionally, the vaginal microbiota modulation performs a fundamental role in the regulation of physiological homeostasis and dysbiosis, which provides us a potential overview of the use of different biotic agents and their implications for female health. The objective of this work was propitiated insights and conception about the influence of probiotics, prebiotics, synbiotics, and postbiotics as adjuvants for prevention/treatment on the main infections that can affect women's health.

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This review assesses the antiviral capabilities of antimicrobial peptides (AMPs) against SARS-CoV-2 and other respiratory viruses, focussing on their therapeutic potential. AMPs, derived from natural sources, exhibit promising antiviral properties by disrupting viral membranes, inhibiting viral entry, and modulating host immune responses. Preclinical studies demonstrate that peptides such as defensins, cathelicidins, and lactoferrin can effectively reduce SARS-CoV-2 replication and inhibit viral spread.

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Social networks consist of a group of individuals connected by family, work, or other interests and facilitated by an online structure or platform. They are also a relatively recent and widely used marketing phenomenon that is constantly evolving. The healthcare field includes professions such as social work, biology, biomedicine, physical education, nursing, pharmacy, physiotherapy, speech therapy, medicine, veterinary medicine, nutrition, dentistry, psychology, and occupational therapy.

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Importance: Women who use heroin in sub-Saharan Africa face elevated HIV risk linked to structural vulnerability including frequent incarceration. However, little is known about the association between incarceration and drug use and HIV outcomes among women who use heroin in Africa.

Objective: To estimate associations between incarceration and adverse HIV-related and drug use-related outcomes among women who used heroin.

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Combined exercise-induced modulation of Notch pathway and muscle quality in senescence-accelerated mice.

Pflugers Arch

January 2025

School of Physical Education and Sport of Ribeirão Preto, University of São Paulo (USP), Avenida Bandeirantes, 3900, Monte Alegre, Ribeirão Preto, São Paulo, 14040-907, Brazil.

The Notch signaling pathway is crucial for skeletal muscle development, regeneration, inflammation, and aging. This study investigated the association between interleukin-10 (IL-10) and the Notch pathway in C2C12 cells, as well as explored the effects of combined endurance and resistance exercise on the Notch and autophagy pathways in the skeletal muscle of senescence-accelerated mouse-resistant 1 Sedentary (SAMR1 CT), SAMR1 exercised (SAMR1 EX), senescence-accelerated prone mouse 8 Sedentary (SAMP8 CT), and SAMP8 exercised (SAMP8 EX). C2C12 myoblasts were transfected with siIL-10.

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This study investigates the effects of three brown seaweed species (, , and ), their pre-processing treatments, and incorporation percentages on the physical and sensory properties of crackers. Significant ( ≤ 0.001) two-way and three-way interactions were observed for moisture content, with seaweed addition generally resulting in drier crackers.

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The active metabolite of vitamin D3, calcitriol (1,25D), is widely recognised for its direct anti-proliferative and pro-differentiation effects. However, 1,25D is calcaemic, which restricts its clinical use for cancer treatment. Non-calcaemic agonists of the vitamin D receptor (VDR) could be better candidates for cancer treatment.

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Propolis is a valuable natural resource for extracting various beneficial compounds. This study explores a sustainable extraction approach for Brazilian green propolis. First, supercritical fluid extraction (SFE) process parameters were optimized (co-solvent: 21.

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Applying Normalisation Process Theory to a peer-delivered complex health intervention for people experiencing homelessness and problem substance use.

Commun Med (Lond)

January 2025

Salvation Army Centre for Addiction Services and Research, Faculty of Social Sciences, Colin Bell Building, University of Stirling, Stirling, Scotland, UK.

Background: The Supporting Harm Reduction through Peer Support (SHARPS) study involved designing and implementing a peer-delivered, harm reduction intervention for people experiencing homelessness and problem substance use. Normalisation Process Theory (NPT) provided a framework for the study.

Methods: Four Peer Navigators (individuals with personal experience of problem substance use and/or homelessness) were recruited and hosted in six third sector (not-for-profit) homelessness services in Scotland and England (United Kingdom).

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Promethazine hydrochloride (PMHC) is a vital drug that is used as an anticholinergic, antipsychotic, antihistaminic, analgesic, sedative, and neuroleptic. However, the overdosage of PMHC also causes reproductive variations, cardiac changes, hypotension, and endocrinal variations. Hence, the detection of PMHC is crucial.

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Umbu-caja and soursop from the Northeast region of Brazil are rich in nutrients and bioactive compounds and are widely processed by the fruit agroindustry. However, there is a lack of research examining the composition and nutritional/technological potential of these co-product fruits. The present study evaluated the nutritional and technological characteristics of umbu-caja and soursop co-product flours (UCF and SCF, respectively), in addition to cytotoxicity in healthy cells.

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