3 results match your criteria: "School Maternity Vila Nova Cachoeirinha[Affiliation]"

Lipidomic assessment of plasma and placenta of women with early-onset preeclampsia.

PLoS One

December 2015

Department of Obstetrics - Federal University of Sao Paulo, Sao Paulo, Sao Paulo, Brazil; Laboratory of Clinical and Experimental Investigation - School Maternity Vila Nova Cachoeirinha, Sao Paulo, Sao Paulo, Brazil; Department of Immunology - University of Sao Paulo, Sao Paulo, Sao Paulo, Brazil.

Introduction: Adipose tissue is responsible for triggering chronic systemic inflammatory response and these changes may be involved in the pathophysiology of preeclampsia.

Objective: To characterize the lipid profile in the placenta and plasma of patients with preeclampsia.

Methodology: Samples were collected from placenta and plasma of 10 pregnant women with preeclampsia and 10 controls.

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Introduction: Preeclampsia is a major cause of maternal morbidity and mortality worldwide, mainly in developing countries. Here we show an example of how is the clinical condition of these patients when they are referred from first care units to a tertiary care teaching maternity in the city of São Paulo, Brazil.

Objectives: To evaluate how has been the approach for preeclamptic women in a big city of Brazil, an example of developing country.

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Introduction: preeclampsia is characterized by intense inflammatory response and an anti-angiogenic state. Maternal obesity has been considered to have important impact on the genesis of preeclampsia as lipotoxicity leads to maternal endothelial dysfunction and chronic inflammation. Here we investigate the plasma lipid profile of preeclamptic women.

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