Glomerular filtration rate (GFR) estimated from serum creatinine predicts total (urine and peritoneal) creatinine clearance in patients on peritoneal dialysis.

Objectives: The aim of this study was to examine the accuracy of the Modification of Diet in Renal Disease (MDRD) equation and the Cockcroft and Gault formula (CCrCG) in predicting total creatinine clearance achieved by residual renal function plus peritoneal dialysis in patients on chronic peritoneal dialysis.

Methods: Total creatinine clearance was defined as peritoneal creatinine clearance (PCcr) plus the average of urine urea and creatinine clearances (cGFR). Correlation analysis and Bland-Altman plot were used to establish the degree of correlation and agreement between the estimations of creatinine clearance achieved by PCcr and the average of cGFR and estimated creatinine clearance based on serum creatinine by using either MDRD equation or the Cockcroft and Gault formula.

Improvement in eGFR in patients with chronic kidney disease attending a nephrology clinic.

Background: The adverse effects arising from late referral to a nephrologist of patients with chronic kidney disease (CKD) are well known. Retrospectively we examined the initial characteristics of patients referred in various stages of CKD to our nephrology division and tried to identify potential baseline factors associated with subsequent changes in estimated glomerular filtration rate (eGFR).

Patients And Methods: Between September 1997 and June 2006 1,443 patients (909 male, 534 female) with CKD, with eGFRs ranging from 15 to 89 ml/min, were referred to our nephrology division and categorized using the National Kidney Foundation classification for CKD based on eGFR.

Validity of health status measures in patients with ulnar wrist disorders.

Purpose: To assess measurement properties and construct validity of health status measures.

Method: Forty-three patients with surgically managed ulnocarpal impingement completed a self-report mail survey, including regional (Disabilities of the Arm, Shoulder and Hand [DASH] questionnaire), disease-specific (Brigham Functional Scale), and generic (Short Form 36 [SF-36] Acute Health Survey) health status measures and questions on condition severity and work status.

Statistical Analysis: Scores were transformed and frequency distributions constructed to compare the distribution of responses to the measures.