4,890 results match your criteria: "Saveetha university[Affiliation]"

Deciphering the complex biological functions and regulatory mechanisms of melatonin.

Hormones (Athens)

January 2025

Department of Physiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Science (SIMATS), Saveetha University, Chennai, India.

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Odontocetes are globally distributed and are foundational to the structure and function of marine food webs, and hence bycatch impacts from gillnet fishing need to be considered in the context of their conservation and population viability. Currently, global gillnet bycatch numbers are unknown yet are estimated to be the greatest in Asia, East Africa, and the west coasts of North and South America. Here we provide the first global meta-analyses of small- and large-scale gillnet bycatch estimates of odontocetes during 1990-2020, compiling population size, estimated gillnet bycatch, and conservation status in support of geographical and species-specific risk estimates.

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Comment on "Drug-Induced Lupus Following mRNA COVID-19 Vaccination and Monoclonal Antibody Infusion for Treatment of COVID-19 Infection".

Kans J Med

September 2024

Department of Research Analytics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, TN, India.

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Objective: This retrospective study aimed to investigate the association between orthodontic treatment and development of temporomandibular disorders (TMDs) in pediatric patients.

Methods: This study analyzed 122 pediatric patients (age 10-18 years) who underwent orthodontic treatment. The inclusion criteria included comprehensive orthodontic records and substantial clinical documentation, while the exclusion criteria targeted preexisting TMDs or syndromes affecting the temporomandibular joint.

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Background: Atrial fibrillation (AF) is the most prevalent form of sustained cardiac arrhythmia, with vascular endothelial growth factor (VEGF) increasingly recognized for its potential role in the pathogenesis of AF through mechanisms involving atrial remodeling, inflammation, and fibrosis. This systematic review aims to synthesize available evidence on the association between VEGF and AF, exploring the implications of VEGF as a biomarker and therapeutic target.

Methods: We conducted a comprehensive search across PubMed, Embase, and Web of Science until November 10 2024, selecting studies based on pre-defined criteria that involve adults with AF and measurements of VEGF levels.

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This study investigates the enhancement of solar cell efficiency using nanofluid cooling systems, focusing on citrate-stabilized and PVP-stabilized silver nanoparticles. Traditional silicon-based and perovskite solar cells were examined to assess the impact of these nanofluids on efficiency improvement and thermal management. A Central Composite Design (CCD) was employed to vary nanoparticle concentration (0.

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A novel method for solving the multiple-attribute decision-making problem is proposed using the complex Diophantine interval-valued Pythagorean normal set (CDIVPNS). This study aims to discuss aggregating operations and how they are interpreted. We discuss the concept of CDIVPN weighted averaging (CDIVPNWA), CDIVPN weighted geometric (CDIVPNWG), generalized CDIVPN weighted averaging (CGDIVPNWA) and generalized CGDIVPN weighted geometric (CGDIVPNWG).

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Background: Tuberculosis (TB) remains a significant health concern in India, especially among households with children and young adolescents aged 6-17 years. Despite ongoing research, there is a knowledge gap regarding specific risk factors for TB within this demographic. This study aims to bridge this gap by examining the association between TB and various socio-demographic factors, including socioeconomic status, nutritional status, and environmental conditions.

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Oral Cancer Stem Cells: A Comprehensive Review of Key Drivers of Treatment Resistance and Tumor Recurrence.

Eur J Pharmacol

January 2025

Department of Conservative Dentistry & Endodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai 600077, Tamil Nadu, India. Electronic address:

Oral squamous cell carcinoma (OSCC) remains a major cause of morbidity and mortality worldwide with high recurrence rates and resistance to conventional therapies. Recent studies have highlighted the pivotal role of oral cancer stem cells (OCSCs) in driving treatment resistance and tumor recurrence. OCSCs possess unique properties, including self-renewal, differentiation potential, and resistance to chemotherapy and radiotherapy, which contribute to their ability to survive treatment and initiate tumor relapse.

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Drug repositioning for Parkinson's disease: an emphasis on artificial intelligence approaches.

Ageing Res Rev

January 2025

Center for Global Health Research, Saveetha Medical College & Hospitals, Saveetha Institute of Medical & Technical Sciences, Saveetha University, Chennai, India; Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran; Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address:

Parkinson's disease (PD) is one of the most incapacitating neurodegenerative diseases (NDDs). PD is the second most common NDD worldwide which affects approximately 1 to 2 percent of people over 65 years. It is an attractive pursuit for artificial intelligence (AI) to contribute to and evolve PD treatments through drug repositioning by repurposing existing drugs, shelved drugs, or even candidates that do not meet the criteria for clinical trials.

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In this present investigation, plant-mediated synthesis of titanium oxide (TiO) nanoparticles was synthesized from seagrass (Thalassia hemprichi) using the hot plate combustion method (HPCM). Synthesized TiO nanoparticles optical, functional, structural, and morphology properties were analyzed by UV-visible spectroscopy, Fourier transform infrared spectroscopy (FT-IR), powder X-ray diffraction (XRD), scanning electron microscopy (SEM), and energy-dispersive X-ray spectroscopy (EDX). SEM analysis confirmed the spherical shape of the TiO nanoparticles were observed in various sizes, viz.

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Targeting Pseudomonas aeruginosa PAO1 pathogenicity: The role of Glycyrrhiza glabra in inhibiting virulence factors and biofilms.

Diagn Microbiol Infect Dis

December 2024

Department of Microbiology, Centre for infectious Diseases, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University (Deemed to be University), Chennai 600 077, Tamil Nadu, India. Electronic address:

Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen posing serious risks to immunocompromised individuals due to its virulence factors and biofilm formation. This study evaluated the efficacy of methanol extract of Glycyrrhiza glabra (G.

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Recent Advancements and Applications of Nanosensors in Oral Health: Revolutionizing Diagnosis and Treatment.

Eur J Dent

December 2024

Department of Dentistry, Oral Health Institute, Hamad Medical Corporation, Doha, Qatar, College of Dental Medicine, Qatar University, Doha, Qatar.

Advances in the field of nanomaterials are laying the foundation for the fabrication of nanosensors that are sensitive, selective, specific, cost-effective, biocompatible, and versatile. Being highly sensitive and selective, nanosensors are crucial in detecting small quantities of analytes and early diagnosis of diseases. These devices, operating on the nanoscale, detect signals, such as physical, chemical, optical, electrochemical, or biological, and then transduce them into a readable form.

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Objectives:  The aim of this study was to determine the effect of apical preparation size and preparation taper on smear layer removal using a metallic needle and a new polymer needle (IrriFlex, Produits Dentaires SA "PD," Vevey, Switzerland).

Materials And Methods:  One hundred and eight single-rooted teeth with one canal were randomly divided into four groups according to the preparation and irrigation needle used: G1-30, 0.04 and IrriFlex ( = 25); G2-25, 0.

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Comparison of marginal fit between milled and three-dimensional printed polymethylmethacrylate prostheses for single crowns, anterior bridges, and pier abutment bridges: An in vitro study.

J Indian Prosthodont Soc

January 2025

Department of Prosthodontics and Implantology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.

Aim: The purpose of this in vitro study was to compare the marginal fit of various three-dimensional (3D) printed and milled polymethylmethacrylate (PMMA) dental prostheses.

Settings And Design: The study was conducted in an in vitro study setting.

Materials And Methods: With a sample size of 45 for each fabrication method, this investigation compared the marginal fit of milled (Group 1) and 3D printed (Group 2) PMMA dental prostheses across different designs.

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Aims: To assess the role of oral health literacy (OHL) in demand for oral healthcare services for missing teeth replacement among adult patients who are visiting the outpatient department of a teaching hospital, Andhra Pradesh, India.

Settings And Design: This cross-sectional study was conducted in a dental teaching institute, Andhra Pradesh, southern part of India.

Materials And Methods: Based on the inclusion and exclusion criteria, a sample of adult participants was selected through systematic random method from the patients who visited the outpatient department.

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