Historical Pathways Highlighting Misgivings and Misinterpretations in the Processes of Tooth Absorption & Resorption.

Historically the physiological or pathological loss of tooth structure in situ was deemed to be due to the 'absorption' of tooth structure due to the removal of the inorganic components of dentin and cementum by osteoclastic (dentinoclastic) cellular activity. This nomenclature and the activity that it represented was considered by almost all dental researchers and clinicians in the 1800s and early 1900s. The shift to the concept of 'resorption' occurred in the first half of the 20th century, with clarity emanating from significant research activity on the pathology of osseous structures, origin of osteoclastic cell types, and the function of periodontal ligament cells.

Fluorescent N-Doped Carbon Dots as a Biocompatible Sensor for Thiophanate-Methyl Detection.

An eco-friendly nitrogen-passivated carbon dot (N-CDs)-based fluorescent sensor was designed for the selective and sensitive detection of thiophanate-methyl, a widely applied fungicide in agriculture. The synthesized N-CDs exhibited robust fluorescence and remarkable photostability, which contributed to the sensor's performance. Notably, the sensor achieved a detection limit as low as 4.

Phytochemical and Antioxidant Analysis of Bioactive Compound Extract from Nelumbo nucifera against Cancer Proteins: In Silico Spectroscopic Approach.

Nelumbo nucifera, an aquatic crop cultivated throughout Asian countries, belongs to the Nelumbonaceae family and has been widely used in traditional medicines with key pharmacological activities such as anti-viral, antipyretic, antioxidant, anti-steroid, anti-inflammatory, anti-arrhythmia, anti-obesity, and anti-aging properties. The present study aims to explore and assess the phytochemical composition, GC-MS profiling, antioxidant efficacy, and the major phytoconstituent phytol subjected to theoretical spectroscopic characterization using the DFT method. The phytochemical profiling of N.

Thaumaturgical Distraction as a Modality for Reducing Dental Anxiety in Children: A Systematic Review.

Background: Dental fear and anxiety have become a major obstacle for children to accept dental treatment. Dental anxiety ranks fifth among common fears.

Aim: The aim of this current systematic review is to assess the effect of thaumaturgical distraction in reducing anxiety in children undergoing dental procedures.

Student's perception of hybrid team-based and case-based learning in undergraduate endodontics education.

Background: Limited studies have explored the use of the hybrid approach combining team-based learning (TBL) and case-based learning (CBL) in dental education. This study evaluates how students perceive the hybrid TBL-CBL approach to learning endodontics and determines whether gender and ethnicity impact students' perceptions.

Methods: The final-year undergraduate Bachelor of Dental Surgery (BDS) students were invited to participate in a hybrid TBL-CBL session.

Effectiveness of 'video-based interventions' of toothbrushing over other interventions on improvement of oral hygiene in children with Autism Spectrum Disorders (ASD): a systematic review and meta-analysis.

Background: Children with Autism exhibit impairment of fine motor co-ordination and sensory sensibilities and hence can directly affect the toothbrushing leading to poor oral hygiene.

Aim: This current systematic review and meta-analysis (SRMA) aims to evaluate the effectiveness of Video-based intervention of toothbrush training over other methods on improvement of oral hygiene in children with autism spectrum disorders (ASD) MATERIALS AND METHODS: Prospero no: (CRD42023450168). 'PubMed', 'Cochrane', 'Ovid' databases were searched from 1 January 1980 to 1 August 2023 using pre-defined search strategy.

A rare case of pigmented seborrhoeic keratosis of scalp.

Seborrheic keratosis (SK) is a prevalent hyperkeratotic dermatological condition characterized by benign proliferation of epidermal keratinocytes, typically occurring in the middle to advanced stages of life. While the trunk is the primary site for lesions, they can also manifest on the extremities, face, and scalp. Although SK is typically benign, there can be morphological overlap with malignant skin lesions, necessitating meticulous differentiation for an accurate diagnosis.

Exploration of magnetic zeolite thin film derived from coal fly ash an efficient sorbent: Application to water treatment.

Fly ash, produced during coal combustion for energy making, which is recognized as an industrial by-product, could lead to environmental health hazards. Subsequently, fly ash found that an exceptional adsorption performance for the removal of various toxic pollutants, the adsorption capacity of fly ash might be altered by introducing physical/chemical stimulation. Successfully converting fly ash into zeolites not only recovers their disposal difficulties but also transforms unwanted materials into merchandisable products for various industrial applications.

A global meta-analysis of gillnet bycatch of toothed whales: Mitigation measures and research gaps.

Odontocetes are globally distributed and are foundational to the structure and function of marine food webs, and hence bycatch impacts from gillnet fishing need to be considered in the context of their conservation and population viability. Currently, global gillnet bycatch numbers are unknown yet are estimated to be the greatest in Asia, East Africa, and the west coasts of North and South America. Here we provide the first global meta-analyses of small- and large-scale gillnet bycatch estimates of odontocetes during 1990-2020, compiling population size, estimated gillnet bycatch, and conservation status in support of geographical and species-specific risk estimates.

Targeting Pseudomonas aeruginosa PAO1 pathogenicity: The role of Glycyrrhiza glabra in inhibiting virulence factors and biofilms.

Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen posing serious risks to immunocompromised individuals due to its virulence factors and biofilm formation. This study evaluated the efficacy of methanol extract of Glycyrrhiza glabra (G.

Synergistic design of CuO/CoFe₂O₄/MWCNTs ternary nanocomposite for enhanced photocatalytic degradation of tetracycline under visible light.

This study involves a novel CuO/CoFe₂O₄/MWCNTs (CCT) nanocomposite, developed by integrating cobalt ferrite (CoFe₂O₄) and copper oxide (CuO) nanoparticles onto multi-walled carbon nanotubes (MWCNTs), for the degradation of tetracycline (TC) under visible light. The photocatalyst was extensively characterized using XRD, HR-SEM, EDX, HR-TEM, UV-Vis, BET, and PL analysis. The synthesized CoFe₂O₄ and CuO nanoparticles exhibited crystallite sizes of 46.

Dysregulated genes in HIGK-treated and their possible association with HNSCC.

The present study aims to identify the differentially expressed genes in HIGK treated with and their possible role in establishing head and neck squamous cell carcinoma. The study design follows a computational approach wherein multiple databases and tools are used to derive the possible association between exposure and the development of HNSCC. The GEOmnibus dataset GSE6927 provided data on the differentially expressed genes in the HIGK treated with .

Preparation and Characterization of Carbon Nanodots from turmeric soot for anti-coliform and anti-oral bacterial applications and as anti-staphylococcal coatings.

In an era where chemical synthesis of nanomaterial is accounting for the generation of toxic wastes, leading to nanotoxicity, the present work focuses on the extraction of carbon nanodots from available natural sources such as turmeric smoke. The extracted carbon nanodots were characterized and their physical and chemical attributes were confirmed. The antibacterial property of the isolated carbon nanodots was tested against coliforms and oral bacteria.

3-Hydroxybenzoic acid inhibits the virulence attributes and disrupts biofilm production in clinical isolates of Acinetobacter baumannii.

Purpose: Acinetobacter baumannii (A. baumannii) is an emerging global public health threat owing to its ability to form biofilms. Here, we evaluated 3-hydroxybenzoic acid (3-HBA), a promising organic compound, for its ability to disrupt biofilm formation and virulence attributes in clinical isolates of A.

Enhancing the efficacy of zinc oxide nanoparticles by beta-carotene conjugation for improved anti-microbial and anti-tumor therapy for dental application.

Zinc oxide NPs (ZnO NPs) are notable in nanomedicine for their exceptional physicochemical and biological properties. This study synthesizes and characterizes beta-carotene-coated ZnO NPs (BT-ZnO NPs) for potential anti-cancer and antimicrobial applications, demonstrating significant efficacy against dental pathogens and oral cancer cells. Scanning Electron Microscopy, EDAX, UV, FTIR, XRD, and Zeta potential analysis of prepared BT-ZnO NPs revealed uniform flower-like crystalline structures with intricate morphology and an average particle size of 38.

Reinforcement and characterization of biopolymer-rhamnolipid nanoparticles: Biocompatibility, in-vitro stability, physico-chemical, rheological and bioactive properties.

In the present study, biopolymer (chitosan and alginate)-reinforced rhamnolipid nanoparticles were prepared and represented as 'ALG-RHLP-NPs' and 'CHI-RHLP-NPs'. The sizes of the nanoparticles ranged from 150 to 300 nm. The encapsulation efficiencies of ALG-RHLP-NPs and CHI-RHLP-NPs were found to be 81.

Identification and Evaluation of Natural Compounds as Potential Inhibitors of NS2B-NS3 Zika Virus Protease: A Computational Approach.

The Zika virus (ZIKV), an arbovirus within the Flavivirus genus, is associated with severe neurological complications, including Guillain-Barré syndrome in affected individuals and microcephaly in infants born to infected mothers. With no approved vaccines or antiviral treatments available, there is an urgent need for effective therapeutic options. This study aimed to identify new natural compounds with inhibitory potential against the NS2B-NS3 protease (PDB ID: 5LC0), an essential enzyme in viral replication.

Automation and miniaturization of high-throughput qPCR for gene expression profiling.

Quantitative PCR (qPCR) is a technique commonly employed in laboratories and core facilities. In our previous study, we had shown the possibility to automate steps in a panel-specific gene expression workflow by pairing Mosquito HV with BioMark HD. Here we aimed to automate the full workflow and explore miniaturization capabilities.

Soil temperature estimation at different depths using machine learning paradigms based on meteorological data.

Knowledge of soil temperature (ST) is important for analysing environmental conditions and climate change. Moreover, ST is a vital element of soil that impacts crop growth as well as the germination of the seeds. In this study, four machine-learning (ML) paradigms including random forest (RF), radial basis neural network (RBNN), multi-layer perceptron neural network (MLPNN), and co-active neuro-fuzzy inference system (CANFIS) were used for estimation of daily ST at different soil depths (i.

Biogenic Synthesis of Silver Nanoparticles for Nanosensor-Based Mercury Detection.

The production of nanoparticles via green methods is a developing study domain due to potential environmental applications. The green synthesis method is very easy, less toxic and eco-friendly when compared to the chemical synthesis method. This study addresses the silver nanoparticle synthesis utilizing the Acorus calamus leaf extract, which was then employed for environmental applications.

Synergistic effect of Zr MOF modified functionalized carbon nano fibres for determination of tert-butylhydroquinone in food samples.

In modern life, people often neglect to consider their eating habits. Antioxidants are primarily used as food additives due to their stability and low toxicity. TBHQ is a commonly used antioxidant in food products as an additive.

Data-Driven Machine Learning Strategy for Designing Metal-Ion-Doped γ-BiMoO Photocatalysts to Enhance Degradation Performance.

Doped semiconductors are often used to improve photocatalytic efficiency and address the challenges of easy recombination of electron-hole pairs and poor photoluminescence. However, the reproducibility and complexity of experimental studies result in time-consuming and less cost-effective studies, and it is difficult to gain insights into the intrinsic properties of doped photocatalysts to control their performance. Introducing a machine learning approach, we constructed a photocatalytic model of transition-metal- and rare earth metal-ion-doped γ-BiMoO.

Differential gene expression profile in treated human gingival keratinocytes and their role in the development of HNSCC.

Background: Periodontitis is considered to be one of the major risk factors associated with cancers of the oral cavity. Periodontogenic pathogens such as and are the important pathogens associated with periodontitis. Chronic exposure to bacterial components induces changes in the nearby cells.