61 results match your criteria: "Saveetha University Chennai[Affiliation]"

The synthesis of polymer/oligomer-stabilized metal nanostructures (MNS) opens up a wide range of possibilities, from fundamental materials science to practical applications in domains such as medicine, catalysis, sensing, and energy. Because of the versatility of this synthetic approach, it is a dynamic and ever-changing field of study. These polymers/oligomers have precise control over the nucleation and growth kinetics, allowing the production of mono-disperse MNS with well-defined properties.

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Recently, interest has surged in the environmental and biomedical applications of two-dimensional transition metal borides, commonly referred to as MBenes. These materials have emerged as promising candidates for energy storage devices, such as batteries and supercapacitors. Additionally, MBenes have shown remarkable catalytic activity due to their high surface area and tunable electronic properties.

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In the vast landscape of materials science, bismuth emerges as a compelling element with unique properties and diverse applications. Its intriguing characteristics and advancements in nanotechnology have propelled bismuth-based nanoparticles to the forefront of scientific exploration, promising breakthroughs in various disciplines. This comprehensive review explores diverse methods for synthesizing bismuth-based nanoparticles and nanocomposites, ranging from conventional approaches such as hydrothermal and sol-gel to innovative techniques such as microwave-assisted, microemulsion, and green synthesis.

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Cancer is a disease that involves uncontrolled cell division triggered by genetic damage to the genes that control cell growth and division. Cancer starts as a localized illness, but subsequently spreads to other areas in the human body (metastasis), making it incurable. Cancer is the second most prevalent cause of mortality worldwide.

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The onset of the coronavirus has highlighted the critical need to swift diagnostic techniques to identify the virus. Metal Organic Frameworks (MOFs) have attracted considerable attention in the field of sensing due to the remarkable characteristics. The present research examines the microwave preparation of naphthalimide-functionalized zeolitic imidazolate framework-8 (NI/ZIF-8) to the detection of coronavirus as a probe.

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Reversible cerebral vasoconstriction syndrome (RCVS) is a rare neurological disorder characterized by transient constriction and dilation of cerebral arteries, leading to severe headaches and neurological deficits. This case report describes a 41-year-old woman with chronic anemia, acute chronic kidney disease, type 2 diabetes mellitus, and rheumatoid arthritis who developed RCVS following transfusion of packed red blood cells (PRBCs). She experienced sudden-onset seizures and a thunderclap headache 5 days post-transfusion.

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Retraction notice to "Cellulose microcrystalline: A promising ecofriendly approach to control Culex quinquefasciatus larvae" [STOTEN 901 (2023) 165952].

Sci Total Environ

December 2024

Post-Graduation Program in Biotechnology and Biodiversity, Federal University of Goi'as, Goiânia, GO, Brazil; Laboratory of Toxicology Applied to the Environment, Goiano Federal Institute - Urutaí Campus, Rodovia Geraldo Silva Nascimento, 2,5 km, Zona Rural, Urutaí, GO, Brazil; Post-Graduation Program in Ecology, Conservation, and Biodiversity, Federal University of Uberlândia, Uberlândia, MG, Brazil; Post-Graduation Program in Conservation of Cerrado Natural Resources, Goiano Federal Institute, Urutaí, GO, Brazil.

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Article Synopsis
  • Lung cancer (LC) is the leading cause of cancer mortality, with significant implications from the interplay between human genetics and microbial cells in the body.
  • The gut-lung axis and interactions between gut and lung microbiomes are believed to influence the progression of lung cancer and other lung diseases.
  • Advances in 16s rDNA sequencing have revealed the role of the lung microbiome in tumor development and treatment responses, suggesting that microbiome-based therapies could be a promising approach for improving LC treatment outcomes.
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This review explores the synergistic relationship between MXenes and artificial intelligence (AI), highlighting recent advancements in predicting and optimizing the properties, synthesis routes, and diverse applications of MXenes and their composites. MXenes possess fascinating characteristics that position them as promising candidates for a variety of technological applications, including energy storage, sensors/detectors, actuators, catalysis, and neuromorphic systems. The integration of AI methodologies provides a robust toolkit to tackle the complexities inherent in MXene research, facilitating property predictions and innovative applications.

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Heterocyclic scaffolds, particularly, pyridine-containing azaheterocycles, constitute a major part of the drugs approved in the past decade. In the present review, we explored the pyridine ring part of US FDA-approved small molecules (2014-2023). The analysis of the approved drugs bearing a pyridine ring revealed that a total of 54 drugs were approved.

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Key Clinical Message: Early recognition and management of familial hypercholesterolemia (FH) are crucial, especially in patients with extensive xanthomas and premature coronary artery disease. Prompt diagnosis and aggressive lipid-lowering therapy can significantly reduce morbidity and mortality rates. Careful clinical assessment in resource-limited settings is essential for optimal outcomes.

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Health Care Access and COVID-19 Vaccination in the United States: Comment.

Med Care

December 2024

Saveetha Medical College and Hospital Saveetha Institute of Medical and Technical Sciences, Saveetha University Chennai, Tamil Nadu, India.

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Background And Aims: The emergence of () antibiotic resistance is an important public health problem worldwide that can negatively affect infection control. Therefore, obtaining knowledge about antibiotic resistance mechanisms is necessary for infection control policies. This study aimed to determine the frequency of class C and D β-lactamases in strains isolated from patients referred to Ardabil hospitals using phenotypic and genotypic tests.

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Background: Mpox infection is a zoonotic illness that resembles smallpox. Vaccination is widely regarded as a vital effective method of preventing mpox, however, there is lack of consensus of effectiveness of a single dose of mpox vaccine in the current 2022-2023 outbreak. We pooled data from real-world studies to evaluate the efficacy of the JYNNEOS vaccination given as a single dosage.

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This research's main objective is to identify the level of contamination in drinking water in Adama town and its environs by employing PIG, GIS and HHRA. The physical-chemical parameters of groundwater were determined, and the results were compared to regional and global drinking water quality guidelines. The pH of groundwater is alkaline, and the contents of Ca, Na, HCO , and F in the majority of samples surpassed the permissible drinking limit.

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Article Synopsis
  • Infections resistant to antibiotics, especially carbapenem-resistant ones, are a serious global health issue, particularly in cases of hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP).
  • The review explores sulbactam-durlobactam therapy (SUL-DUR), assessing its approval process, how it works, and its potential in treating these bacterial infections.
  • SUL-DUR, known as Xacduro, has shown safety and effectiveness in clinical trials, making it a promising treatment alternative compared to traditional options like colistin for VAP, HAP, and related infections.
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MXene-based composites in smart wound healing and dressings.

Nanoscale Adv

July 2024

Department of Biomedical Engineering, Faculty of Engineering and Natural Sciences, Istinye University Istanbul 34396 Turkey

MXenes, a class of two-dimensional materials, exhibit considerable potential in wound healing and dressing applications due to their distinctive attributes, including biocompatibility, expansive specific surface area, hydrophilicity, excellent electrical conductivity, unique mechanical properties, facile surface functionalization, and tunable band gaps. These materials serve as a foundation for the development of advanced wound healing materials, offering multifunctional nanoplatforms with theranostic capabilities. Key advantages of MXene-based materials in wound healing and dressings encompass potent antibacterial properties, hemostatic potential, pro-proliferative attributes, photothermal effects, and facilitation of cell growth.

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Article Synopsis
  • - The study investigates the prevalence of Hepatitis B (HBV) and Hepatitis C (HCV) among men who have sex with men (MSM) living with HIV, identifying a considerable global burden of these co-infections.
  • - Using a systematic review and meta-analysis of 56 studies involving over 307,000 participants, researchers found a pooled prevalence of 7% for HCV and 9% for HBV among the HIV-infected MSM population.
  • - Results revealed geographic variation in prevalence rates, with the lowest rates in Asia (5.84% for HCV) and the highest in Europe (7.76% for HCV), emphasizing the need for future research on factors contributing to these
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Article Synopsis
  • This study introduces eco-friendly methods to produce Zn-doped nickel oxide nanoparticles (Zn:NiO NPs) using aloe vera gel extract and glucose as fuel sources.
  • Characterization techniques like PXRD and electron microscopy reveal that the nanoparticles have a specific crystal structure and unique spongy, spherical, and porous features.
  • The research suggests that Zn:NiO NPs show promising electrical properties, making them a viable and cost-effective material for supercapacitor applications in the future.
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Background: Immune checkpoint inhibitors (ICIs) have uncommon associations with cardiotoxicity, yet these cardiotoxic effects are associated with high mortality. An accurate assessment of risk for cardiotoxicity is essential for clinical decision-making, but data from randomized controlled trials often differ from real-world observational studies.

Methods And Results: A systematic search of PubMed, Embase, Cochrane Library, and Scopus was performed, including phase II and III randomized controlled trials (RCTs) and observational studies (OSs) reporting myocarditis or pericardial disease, myocardial infarction, or stroke with an immunotherapy.

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Pemphigus vulgaris (PV) is a chronic autoimmune blistering disorder characterized by the loss of intraepithelial adhesion affecting the skin and mucous membranes, predominantly affects females in their fifth and sixth decades of life. Due to its rare occurrence in children and adolescents, there is often a delay in diagnosis and treatment in this age group. PV should always be considered in the differential diagnosis of oral ulcerative and vesiculobullous lesions in both children and adolescents.

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A clinical case concerning an extraordinary maxillary second molar having two separate palatal roots.

Clin Case Rep

May 2024

Department of Dental Research, Center for Global health Research, Saveetha Institute of Medical and Technical Sciences Saveetha Medical College and Hospitals, Saveetha University Chennai Tamil Nadu India.

Key Clinical Message: Main objective of root canal therapy is to locate all the canals, cleaning and shaping, and obturation to obtain fluid tight seal. Failure to locate all canals can lead to the failure of root canal therapy.

Abstract: Variation of pulp aperture, among teeth with multiple roots, constitutes recurring issue during diagnosing and completing efficient endodontic procedures.

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